Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maisy Yeager"'
Autor:
Chi B. Vu, Min Ding, Ericka L. Benson, Robert Kleemann, Martine C. Morrison, Rick B. Vega, Diana Y. Lee, Maisy Yeager, Michael R. Jirousek, Andrew J. Nichols, Guosheng Liang, Teake Kooistra, Michael Zimmer, Jill C. Milne, Dominic Picarella, Peter Y. Wielinga, Feng Liu, Jay D. Horton, Pradeep Bista
Publikováno v:
Hepatology Communications
CAT-2003 is a novel conjugate of eicosapentaenoic acid (EPA) and niacin designed to be hydrolyzed by fatty acid amide hydrolase to release EPA inside cells at the endoplasmic reticulum. In cultured liver cells, CAT-2003 blocked the maturation of ster
Autor:
Amal Ting, Abby Sewell, Cecilia Pena-Rasgado, Dominic Picarella, Antonio E. Lacerda, Maisy Yeager, Chi B. Vu, Chandran Sachin, Pallavi Lonkar, Robert J. Bridges, A. Nichols, Curtis Bordwell, Feng Liu, Allison Wensley
Publikováno v:
Journal of medicinal chemistry. 60(1)
A depressed autophagy has previously been reported in cystic fibrosis patients with the common F508del-CFTR mutation. This report describes the synthesis and preliminary biological characterization of a novel series of autophagy activators involving
Autor:
Andrew J. Nichols, Pallavi Lonkar, Jean Bemis, Michael R. Jirousek, Michael Zimmer, Diana Lee, Jill C. Milne, Adam Shoelson, Amal Ting, Dominic Picarella, Maisy Yeager, Ericka L. Benson, Feng Liu, Smith Jesse J, David Carney, Allison Wensley, Chi B. Vu, Richard Fahrner, P. Bista
Publikováno v:
Journal of medicinal chemistry. 59(3)
This report describes the synthesis and preliminary biological characterization of novel fatty acid niacin conjugates and fatty acid salicylate conjugates. These molecular entities were created by covalently linking two bioactive molecules, either ni