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The Protein Tyrosine Phosphatase SHP-2 Regulates Interleukin-1-induced ERK Activation in Fibroblasts
Autor:
Chung-Wai Chow, Gregory P. Downey, Qin Wang, Christopher A. McCulloch, Christina Shek, Eric Vachon, Maria Teresa Herrera-Abreu, Mairi MacGillivray, Gen-Sheng Feng, Katherine A. Siminovitch
Publikováno v:
Journal of Biological Chemistry. 278:27190-27198
Focal adhesion complexes are actin-rich, cytoskeletal structures that mediate cell adhesion to the substratum and also selectively regulate signal transduction pathways required for interleukin (IL)-1beta signaling to the MAP kinase, ERK. IL-1-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942a5e750022071cfb96337262277e75
https://doi.org/10.1074/jbc.m213083200
https://doi.org/10.1074/jbc.m213083200
