Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Mairena, Martín"'
Autor:
Alejandro Sánchez Melgar, Valentina Vultaggio-Poma, José Luis Albasanz, Francesco Di Virgilio, Mairena Martín
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S256- (2023)
Externí odkaz:
https://doaj.org/article/c0736958b65f47e2ae927adb89c4e4a3
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S143- (2023)
Externí odkaz:
https://doaj.org/article/854c144d07da4336a84dea489685581a
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3292 (2023)
Caffeine is a psychoactive substance that is widely consumed by individuals of various demographics, including pregnant women. It can readily cross the blood–brain and placental barriers, easily reaching the fetal brain. In addition, caffeine has a
Externí odkaz:
https://doaj.org/article/edf0131cd12c4e25950c97cda3077cc9
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still p
Externí odkaz:
https://doaj.org/article/61bdf7f71d1343b3b72d107d55b4f462
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Gliomas are the most common and aggressive primary tumors in the central nervous system. The nucleoside adenosine is considered to be one major constituent within the tumor microenvironment. The adenosine level mainly depends on two enzymatic activit
Externí odkaz:
https://doaj.org/article/36daa0fa6c5f4def8c85d9280757c432
Autor:
Ramon Guixà-González, José L. Albasanz, Ismael Rodriguez-Espigares, Manuel Pastor, Ferran Sanz, Maria Martí-Solano, Moutusi Manna, Hector Martinez-Seara, Peter W. Hildebrand, Mairena Martín, Jana Selent
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
G-protein-coupled receptors trigger several signalling pathways and their activity was proposed to be allosteric modulated by cholesterol. Here the authors use molecular dynamics simulations and ligand binding assays to show that membrane cholesterol
Externí odkaz:
https://doaj.org/article/6bfe51cbb81e47ca99f372882e589358
Autor:
Alejandro Sánchez-Melgar, José Luis Albasanz, Christian Griñán-Ferré, Mercè Pallàs, Mairena Martín
Publikováno v:
Cells, Vol 9, Iss 7, p 1628 (2020)
Adenosine (ARs) and metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors (GPCRs) that are modulated in the brain of SAMP8 mice, an animal model of Alzheimer’s disease (AD). In the present work, it is shown the presence of ARs a
Externí odkaz:
https://doaj.org/article/aab331f4f15149b5a8c268905c76ef93
Autor:
Gemma Navarro, Eva Martínez-Pinilla, Alejandro Sánchez-Melgar, Raquel Ortiz, Véronique Noé, Mairena Martín, Carlos Ciudad, Rafael Franco
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176067 (2017)
The mode of action of trans-resveratrol, a promising lead compound for the development of neuroprotective drugs, is unknown. Data from a functional genomics study were retrieved with the aim to find differentially expressed genes that may be involved
Externí odkaz:
https://doaj.org/article/b4c914dadac94a3aa87a81469218f615
Publikováno v:
International journal of molecular sciences. 23(23)
Febrile seizures (FS) are one of the most common seizure disorders in childhood which are classified into short and prolonged, depending on their duration. Short FS are usually considered as benign. However, epidemiological studies have shown an asso
Publikováno v:
Frontiers in endocrinology. 13
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still p