Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mairead Duke"'
Autor:
Matthias Staufenbiel, Christine Sturchler-Pierrat, Birgit Ledermann, Dorothee Abramowski, Claudia Mistl, Michael E. Calhoun, Paolo Paganetti, Kurt Bürki, Karl-Heinz Wiederhold, Caroline Waridel, Mathias Jucker, Mairead Duke, Sabin Rothacher, Bernd Sommer, Alphonse Probst, Peter Frey
Publikováno v:
Proceedings of the National Academy of Sciences. 94:13287-13292
Mutations in the amyloid precursor protein (APP) gene cause early-onset familial Alzheimer disease (AD) by affecting the formation of the amyloid β (Aβ) peptide, the major constituent of AD plaques. We expressed human APP 751 containing these mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786858b5a6db5710cfe8f7417e131aba
https://doi.org/10.1073/pnas.94.24.13287
https://doi.org/10.1073/pnas.94.24.13287
Autor:
Kerstin Andrä, Karl-Heinz Wiederhold, Kurt Bürki, Dorothee Abramowski, Alphonse Probst, Bernd Sommer, Michel Goedert, Matthias Staufenbiel, Mairead Duke
Publikováno v:
Neurobiology of Aging. 17:183-190
The beta-amyloid precursor protein (APP) carries mutations in codons 717 or 670/671, which cosegregate with familial forms of Alzheimer's disease (AD). As an initial step to study the related pathogenetic mechanisms in vivo we have generated transgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e235c04c4977692214fd115c0945cfb6
https://doi.org/10.1016/0197-4580(95)02066-7
https://doi.org/10.1016/0197-4580(95)02066-7
Publikováno v:
Nature Biotechnology. 10:784-789
We report the production of recombinant human lactoferrin in Aspergillus oryzae. Expression of human lactoferrin (hLF), a 78 kD glycoprotein, was achieved by placing the cDNA under the control of the A. oryzae alpha-amylase promoter and the 3' flanki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018af879d6342d0f7fa6c4e6b6bd0752
https://doi.org/10.1038/nbt0792-784
https://doi.org/10.1038/nbt0792-784