Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maire E. Doyle"'
Autor:
Caio Henrique Mazucanti, Vernon Kennedy, Jr., Hasitha U. Premathilake, Maire E. Doyle, Jane Tian, Qing-Rong Liu, Jennifer O’Connell, Simonetta Camandola, Josephine M. Egan
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112903- (2023)
Summary: The choroid plexus (CP) is a source of trophic factors for the developing and mature brain. Insulin is produced in epithelial cells of the CP (EChPs), and its secretion is stimulated by Htr2c-mediated signaling. We modulated insulin expressi
Externí odkaz:
https://doaj.org/article/643acc5a5f964316adb37029ebb0c598
Autor:
Na Yang, James R. Occean, Daniël P. Melters, Changyou Shi, Lin Wang, Stephanie Stransky, Maire E. Doyle, Chang-Yi Cui, Michael Delannoy, Jinshui Fan, Eliza Slama, Josephine M. Egan, Supriyo De, Steven C. Cunningham, Rafael de Cabo, Simone Sidoli, Yamini Dalal, Payel Sen
Publikováno v:
bioRxiv
SummaryEpigenetic alterations are a key hallmark of aging but have been limitedly explored in tissues. Here, using naturally aged murine liver as a model and extending to other quiescent tissues, we find that aging is driven by temporal chromatin alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e112a82c35a8cea50f977bef7b133727
https://europepmc.org/articles/PMC9949032/
https://europepmc.org/articles/PMC9949032/
Autor:
Kanikkai Raja Aseer, Caio Henrique Mazucanti, Jennifer F. O’Connell, Isabel González-Mariscal, Anjali Verma, Qin Yao, Christopher Dunn, Qing-Rong Liu, Josephine M. Egan, Máire E. Doyle
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101917- (2024)
Externí odkaz:
https://doaj.org/article/fc2998fbbee947e0b1e63770929e59bb
Autor:
Kanikkai Raja Aseer, Caio Henrique Mazucanti, Jennifer F. O’Connell, Isabel González-Mariscal, Anjali Verma, Qin Yao, Christopher Dunn, Qing-Rong Liu, Josephine M. Egan, Máire E. Doyle
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101906- (2024)
Objective: Type 1 diabetes (T1D) occurs because of islet infiltration by autoreactive immune cells leading to destruction of beta cells and it is becoming evident that beta cell dysfunction partakes in this process. We previously reported that geneti
Externí odkaz:
https://doaj.org/article/f9b137e5ebbd4b2fba8b127ac6e303d3
Autor:
Wook Kim, Zhuo Liu, Maire E Doyle, Yu-Kyong Shin, Olga D Carlson, Jennifer Fiori, Shekhar Gadkaree, Eun Kyung Lee, Qi Zong Lao, Josephine M Egan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb7e708d0ed485ba0863e1cc234fbbc
https://doi.org/10.1210/endo-meetings.2011.part1.or2.or01-4
https://doi.org/10.1210/endo-meetings.2011.part1.or2.or01-4
Autor:
Yoo Kim, Sudeep Gautam, Kanikkai Raja Aseer, Jaekwan Kim, Prabha Chandrasekaran, Caio Henrique Mazucanti, Paritosh Ghosh, Jennifer F. O’Connell, Máire E. Doyle, Ashley Appleton, Elin Lehrmann, Qing-Rong Liu, Josephine M. Egan
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-13 (2020)
Abstract Cannabinoid 1 receptor (CB1R) expression is upregulated in the liver with viral hepatitis, cirrhosis, and both alcoholic and non-alcoholic fatty liver disease (FLD), whereas its expression is muted under usual physiological conditions. Inhib
Externí odkaz:
https://doaj.org/article/9666fd9589f04fc68c08c674919873b5