Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Mairéad G. McNamara"'
Autor:
Daniel Netto, Melissa Frizziero, Victoria Foy, Mairéad G. McNamara, Alison Backen, Richard A. Hubner
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 5206-5223 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a significant cause of cancer-associated mortality, with a rising global incidence. A paucity of strong predictive risk factors mean screening programmes are difficult to implement. Historically, a lack of i
Externí odkaz:
https://doaj.org/article/82cdbede92d547bc8b5e3d4f02cac346
Autor:
Victoria Foy, Mairéad G. McNamara, Juan W. Valle, Angela Lamarca, Julien Edeline, Richard A. Hubner
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8665-8685 (2023)
The treatment of advanced unresectable HCC (aHCC) remains a clinical challenge, with limited therapeutic options and poor prognosis. The results of IMbrave150 and HIMALAYA have changed the treatment paradigm for HCC and established immune checkpoint
Externí odkaz:
https://doaj.org/article/e6075971c8d843248347bb5a70df88af
Autor:
Mairéad G. McNamara, Jayne Swain, Zoe Craig, Rohini Sharma, Olusola Faluyi, Jonathan Wadsley, Carys Morgan, Lucy R. Wall, Ian Chau, Nick Reed, Debashis Sarker, Jane Margetts, Daniel Krell, Judith Cave, Sharmila Sothi, Alan Anthoney, Christopher Bell, Alkesh Patel, Jamie B. Oughton, David A. Cairns, Wasat Mansoor, Angela Lamarca, Richard A. Hubner, Juan W. Valle
Publikováno v:
EClinicalMedicine, Vol 60, Iss , Pp 102015- (2023)
Summary: Background: The prognosis for patients with poorly-differentiated extra-pulmonary neuroendocrine carcinoma (PD-EP-NEC) is poor. A recognised first-line (1L) treatment for advanced disease is etoposide/platinum-based chemotherapy with no stan
Externí odkaz:
https://doaj.org/article/17e61c62deeb4eef9d3d7c4b9df3c376
Autor:
Zainul-Abedin Kapacee, Jennifer Allison, Mohammed Dawod, Xin Wang, Melissa Frizziero, Bipasha Chakrabarty, Prakash Manoharan, Catherine McBain, Was Mansoor, Angela Lamarca, Richard Hubner, Juan W. Valle, Mairéad G. McNamara
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 5110-5125 (2022)
Background: Brain metastases (BMs) in patients with extra-pulmonary neuroendocrine neoplasms (EP–NENs) are rare, and limited clinical information is available. The aim of this study was to detail the clinicopathological features, management and out
Externí odkaz:
https://doaj.org/article/8201b5f585ae4da79ba4c75470b0d907
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Neuroendocrine neoplasms (NENs) are rare malignancies arising most commonly in the gastrointestinal and bronchopulmonary systems. Neuroendocrine carcinomas (NECs) are a subgroup of NENs characterised by aggressive tumour biology, poor differentiation
Externí odkaz:
https://doaj.org/article/733af2b9707a4c1d8e811a72c0688cc5
Autor:
Sarah Clelland, Christina L. Nuttall, Helen E. Stott, Joseph Cope, Natalie L. Barratt, Kelly Farrell, Manyi V. Eyong, Jack P. Gleeson, Angela Lamarca, Richard A. Hubner, Juan W. Valle, Mairéad G. McNamara
Publikováno v:
Healthcare, Vol 11, Iss 20, p 2802 (2023)
Advanced pancreatic cancer is associated with a poor prognosis, often less than 1 year. Honest prognosis discussions guide early community palliative care services input, facilitating timely advance care planning and improving quality of life. The ai
Externí odkaz:
https://doaj.org/article/1ae44ad74f7743bb8ce29cca07591869
Autor:
Saroj Vadhan‐Raj, Mairéad G. McNamara, Marino Venerito, Hanno Riess, Eileen M. O'Reilly, Michael J. Overman, Xiao Zhou, Ujjwala Vijapurkar, Simrati Kaul, Peter Wildgoose, Alok A. Khorana
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6196-6204 (2020)
Abstract Background Pancreatic cancer patients are at risk for venous thromboembolism (VTE); the value of thromboprophylaxis has not been definitively established. Methods This trial randomized cancer patients initiating a new regimen and at high ris
Externí odkaz:
https://doaj.org/article/416b048f2b634005b513dee8b0b182ef
Autor:
Mairéad G. McNamara, Melissa Frizziero, Timothy Jacobs, Angela Lamarca, Richard A. Hubner, Juan W. Valle, Eitan Amir
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: There is no standard second-line treatment for patients with advanced extra-pulmonary poorly differentiated neuroendocrine carcinoma (EP-PD-NEC). This study explored data evaluating second-line treatment in these patients. Methods: A sear
Externí odkaz:
https://doaj.org/article/ac9dacadd8cb4122b077bd15b826da88
Autor:
Alok A. Khorana, Mairéad G. McNamara, Ajay K. Kakkar, Michael B. Streiff, Hanno Riess, Ujjwala Vijapurkar, Simrati Kaul, Peter Wildgoose, Gerald A. Soff
Publikováno v:
TH Open, Vol 04, Iss 02, Pp e107-e112 (2020)
Introduction In the CASSINI study, rivaroxaban thromboprophylaxis significantly reduced primary venous thromboembolism (VTE) endpoints during the intervention period, but several thromboembolic events designated as secondary efficacy endpoints were n
Externí odkaz:
https://doaj.org/article/ee99dcca8b064679be805e3206169d47
Autor:
Jaseela Chiramel, Alison C. Backen, Rille Pihlak, Angela Lamarca, Melissa Frizziero, Noor-ul-Ain Tariq, Richard A. Hubner, Juan W. Valle, Eitan Amir, Mairéad G. McNamara
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 5, p 909 (2017)
Overexpression of epidermal growth factor receptors (EGFR) occurs in >90% of pancreatic ductal adenocarcinomas (PDACs) and is associated with a poorer prognosis. A systematic review of electronic databases identified studies exploring the addition of
Externí odkaz:
https://doaj.org/article/2ac0cd4aa1bf4fa282ccb678be137acb