Innovative technology-enhanced social work service during COVID-19: How ‘Garden on the Balcony’ promoted resilience, community bonds and a green lifestyle

Autor: Yixuan Wang, Qin Gao, Fei Pei, Yi Wang, Zhen Cheng, Ji Zhang, Yang Wu

Publikováno v: Qualitative Social Work

The ongoing COVID-19 pandemic has motivated social workers to reckon with and transform traditions in service delivery. The development, application, and evaluation of technology-enhanced practices have become more vital than ever. Garden on the Balc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b351a609ca0540b064cf962992d79b
https://doi.org/10.1177/14733250211059431

Matrix decomposition in meta‐analysis for extraction of adverse event pattern and patient‐level safety profile

Autor: Kentaro Matsuura, Jun Tsuchida, Shuji Ando, Takashi Sozu

Publikováno v: Pharmaceutical Statistics

The purpose of assessing adverse events (AEs) in clinical studies is to evaluate what AE patterns are likely to occur during treatment. In contrast, it is difficult to specify which of these patterns occurs in each patient. To tackle this challenging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9388d40b9c179095a19c6dadac593779
http://europepmc.org/articles/PMC8359197

A confidence function‐based posterior probability design for phase II cancer trials

Autor: Minghua Shan

Publikováno v: Pharmaceutical Statistics

Single‐arm one‐ or multi‐stage study designs are commonly used in phase II oncology development when the primary outcome of interest is tumor response, a binary variable. Both two‐ and three‐outcome designs are available. Simon two‐stage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53bade29ec8609bf777482e5324e646
https://doi.org/10.1002/pst.2089

Empirical evaluation of the implementation of the EMA guideline on missing data in confirmatory clinical trials: Specification of mixed models for longitudinal data in study protocols

Autor: Florian Lasch, Armin Koch, Sebastian Häckl

Publikováno v: Pharmaceutical Statistics
64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS); 20190908-20190911; Dortmund; DOCAbstr. 120 /20190906/

In confirmatory clinical trials, the pre-specification of the primary analysis model is a universally accepted scientific principle to allow strict control of the type-I-error. Accordingly both the ICH E9 guideline and the EMA guideline on missing da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6e7826e8c6b5b7a4f684086ad901a3
http://europepmc.org/articles/PMC6899721

Potential impact of COVID-19 on ongoing clinical trials: a simulation study with the neurological Yale Global Tic Severity Scale based on the CANNA-TICS study

Autor: Kirsten R. Müller-Vahl, Florian Lasch, Lorenzo Guizzaro, Armin Koch, Lukas Aguirre Davila

Publikováno v: Pharmaceutical statistics, 20(3):675-691
Pharmaceutical Statistics

The COVID‐19 pandemic has manifold impacts on clinical trials. In response, drug regulatory agencies and public health bodies have issued guidance on how to assess potential impacts on ongoing clinical trials and stress the importance of a risk‐a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb608480763d895556af1632d8c112e8
https://repository.publisso.de/resource/frl:6432013