Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mailys Le Dévéhat"'
Autor:
Nabil Seidah, Vatsal Sachan, Mailys Le Dévéhat, Anna Roubtsova, Rachid Essalmani, Damien Garçon, Delia Susan-Resiga, Stéphanie Duval, Sahar Mikaeeli, Josée Hamelin, Alexandra Evagelidis, Michael Chong, Guillaume Pare, Elizabeta Chernetsova, Zu-hua Gao, Isabelle Robillard, Matthieu Ruiz, Vincent Quoc-Huy Trinh, Jennifer Estall, May Faraj, Jean-Francois Laurendeau, Richard Austin, Martin Sauvageau, Annik Prat, Robert Scott Kiss
Epidemiological evidence links the proprotein convertase subtilisin/kexin 7 (PCSK7) to triglyceride (TG) metabolism. PCSK7-SNPs gain-of-function and loss-of-function variants were associated with higher and lower levels of plasma apoB and TGs, respec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7611159c671b9f23fc40d49502551155
https://doi.org/10.21203/rs.3.rs-2724841/v1
https://doi.org/10.21203/rs.3.rs-2724841/v1
Autor:
Carole Fruchart Gaillard, Ali Ben Djoudi Ouadda, Lidia Ciccone, Emmanuelle Girard, Sepideh Mikaeeli, Alexandra Evagelidis, Maïlys Le Dévéhat, Delia Susan-Resiga, Evelyne Cassar Lajeunesse, Hervé Nozach, Oscar Henrique Pereira Ramos, Aurélien Thureau, Pierre Legrand, Annik Prat, Vincent Dive, Nabil G. Seidah
Publikováno v:
Molecular Metabolism, Vol 67, Iss , Pp 101662- (2023)
Objective: The liver-derived circulating PCSK9 enhances the degradation of the LDL receptor (LDLR) in endosomes/lysosomes. PCSK9 inhibition or silencing is presently used in clinics worldwide to reduce LDL-cholesterol, resulting in lower incidence of
Externí odkaz:
https://doaj.org/article/25b8b2644d1147d09b7ec706733b10c7
Autor:
Rachid Essalmani, Ursula Andréo, Alexandra Evagelidis, Maïlys Le Dévéhat, Oscar Henrique Pereira Ramos, Carole Fruchart Gaillard, Delia Susan-Resiga, Éric A. Cohen, Nabil G. Seidah
Publikováno v:
Viruses, Vol 15, Iss 2, p 360 (2023)
Proprotein convertases activate various envelope glycoproteins and participate in cellular entry of many viruses. We recently showed that the convertase furin is critical for the infectivity of SARS-CoV-2, which requires cleavage of its spike protein
Externí odkaz:
https://doaj.org/article/a6d5e3e203b24f989c24deddb4fb9949