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Receptor Conformations Involved in Dopamine D2L Receptor Functional Selectivity Induced by Selected Transmembrane-5 Serine Mutations

Autor: Urban, J. D., Bhattacharya, S., Mailman, R. B., Vaidehi, N., Fowler, J. C.

Although functional selectivity is now widely accepted, the molecular basis is poorly understood. We have studied how aspects of transmembrane region 5 (TM5) of the dopamine D2L receptor interacts with three rationally selected rigid ligands (dihydre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bec55366e2273ad4c72a23d2b865cedc

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Akademický článek

Genome scans reveal signals of selection associated with pollution in fish populations of Basilichthys microlepidotus, an endemic species of Chile.

Autor: Vega-Retter, Caren¹ (AUTHOR), Rojas-Hernández, Noemi¹ (AUTHOR), Cortés-Miranda, Jorge¹ (AUTHOR), Véliz, David^1,2 (AUTHOR), Rico, Ciro³ (AUTHOR) ciro.rico@csic.es

Publikováno v: Scientific Reports. 7/8/2024, Vol. 14 Issue 1, p1-12. 12p.

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Differential involvement of striato- and cerebello-thalamo-cortical pathways in tremor- and akinetic/rigid-predominant Parkinson's disease

Autor: Kawaguchi, A., Mailman, R. B., Lee, S., Huang, X., Truong, Y., Sen, S., Lewis, M. M., Du, G.

Parkinson's disease (PD) presents clinically with varying degrees of resting tremor, rigidity, and bradykinesia. For decades, striatal-thalamo-cortical (STC) dysfunction has been implied in bradykinesia and rigidity, but does not explain resting trem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f70395f55e2302ba8952e75747a497b8

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Asymmetrical lateral ventricular enlargement in Parkinson’s disease

Autor: Lewis, M. M., Gouttard, S., Poole, R., Mailman, R. B., Styner, M., Gu, H., Smith, A. B., McKeown, M. J., Zhu, H., Huang, X., Barbero, X., Li, Y.

A recent case report suggested the presence of asymmetrical lateral ventricular enlargement associated with motor asymmetry in Parkinson’s disease (PD). The current study explored these associations further.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::803aca818076265263448578f3516c71

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Dopamine D1–D5 Receptors in Brain Nuclei: Implications for Health and Disease.

Autor: Kawahata, Ichiro¹ (AUTHOR) kawahata@tohoku.ac.jp, Finkelstein, David I.² (AUTHOR) david.finkelstein@florey.edu.au, Fukunaga, Kohji¹ (AUTHOR)

Publikováno v: Receptors. Jun2024, Vol. 3 Issue 2, p155-181. 27p.

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BOOSTED ANTIBACTERIAL EFFICACY: DI AND TRIORGANOTIN COMPLEXES VIA 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID.

Autor: Al-Shemary, Rana S.¹, Jasem, Hadeer², Hadi, Angham G.³ sci.angam.ganem@uobabylon.edu.iq, Baqir, Sadiq J.⁴

Publikováno v: Bulletin of the Chemical Society of Ethiopia. 2024, Vol. 38 Issue 3, p647-655. 9p.

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Targeting GRP75 with a Chlorpromazine Derivative Inhibits Endometrial Cancer Progression Through GRP75–IP3R‐Ca²⁺‐AMPK Axis.

Autor: Wang, Qi^1,2 (AUTHOR), Li, Lijuan¹ (AUTHOR), Gao, Xiaoyan¹ (AUTHOR), Zhang, Chunxue¹ (AUTHOR), Xu, Chen¹ (AUTHOR), Song, Lingyi² (AUTHOR), Li, Jian² (AUTHOR), Sun, Xiao¹ (AUTHOR) sunxiao@shsmu.edu.cn, Mao, Fei² (AUTHOR) maofei@mail.ecust.edu.cn, Wang, Yudong¹ (AUTHOR) wangyudong@shsmu.edu.cn

Publikováno v: Advanced Science. 4/17/2024, Vol. 11 Issue 15, p1-15. 15p.

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