Detection of long-range electrostatic interactions between charged molecules by means of Fluorescence Correlation Spectroscopy

Autor: Nardecchia, Ilaria, Lechelon, Mathias, Gori, Matteo, Donato, Irene, Preto, Jordane, Floriani, Elena, Jaeger, Sebastien, Mailfert, Sebastien, Marguet, Didier, Ferrier, Pierre, Pettini, Marco

Publikováno v: Phys. Rev. E 96, 022403 (2017)

The present paper deals with an experimental feasibility study concerning the detection of long- range intermolecular interactions through molecular diffusion behavior in solution. This follows previous analyses, theoretical and numerical, where it w

Externí odkaz: http://arxiv.org/abs/1705.08285

Experimental evidence for long-distance electrodynamic intermolecular forces

Autor: Lechelon, Mathias, Meriguet, Yoann, Gori, Matteo, Ruffenach, Sandra, Nardecchia, Ilaria, Floriani, Elena, Kudashova, Anastasiia, Coquillat, Dominique, Teppe, Frédéric, Mailfert, Sébastien, Marguet, Didier, Ferrier, Pierre, Varani, Luca, Sturgis, James, Torres, Jeremie, Pettini, Marco

Publikováno v: Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), In press

International audience; Both Classical and Quantum Electrodynamics predict the existence of dipole-dipole long-range electrodynamic intermolecular forces, however these have never been hitherto experimentally observed. The discovery of completely new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e249b9c6e31f01564a8c9148fe477c35
https://hal.archives-ouvertes.fr/hal-03259009

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TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T Cells

Autor: Xia, Fan, Qian, Cheng-Rui, Xun, Zhou, Hamon, Yannick, Sartre, Anne-Marie, Formisano, Anthony, Mailfert, Sébastien, Phelipot, Marie-Claire, Billaudeau, Cyrille, Jaeger, Sébastien, Nunès, Jacques A., Guo, Xiao-Jun, He, Hai-Tao

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2018, 9, ⟨10.3389/fimmu.2018.02864⟩
Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.02864⟩

International audience; T cell activation is initiated upon ligand engagement of the T cell receptor (TCR) and costimulatory receptors. The CD28 molecule acts as a major costimulatory receptor in promoting full activation of naive T cells. However, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e5194b7dc023be4a189c5a764ab51596
https://hal-amu.archives-ouvertes.fr/hal-02084941

Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation

Autor: Chouaki-Benmansour, Nassima, Ruminski, Kilian, Sartre, Anne-Marie, Phelipot, Marie-Claire, Salles, Audrey, Bergot, Elise, Wu, Ambroise, Chicanne, Gaëtan, Fallet, Mathieu, Brustlein, Sophie, Billaudeau, Cyrille, Formisano, Anthony, Mailfert, Sébastien, Payrastre, Bernard, Marguet, Didier, Brasselet, Sophie, He, Hai-Tao

Publikováno v: Scientific Reports (8), 1-16. (2018)

Phosphoinositides (PIs) play important roles in numerous membrane-based cellular activities. However, their involvement in the mechanism of T cell receptor (TCR) signal transduction across the plasma membrane (PM) is poorly defined. Here, we investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1582::bb85e022fbcff823f8f0ae8a52697fff
http://prodinra.inra.fr/record/428683