Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maile A Henson"'
Autor:
Maile A Henson, Rylan S Larsen, Shelikha N Lawson, Isabel Pérez-Otaño, Nobuki Nakanishi, Stuart A Lipton, Benjamin D Philpot
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42327 (2012)
Glutamatergic synapse maturation is critically dependent upon activation of NMDA-type glutamate receptors (NMDARs); however, the contributions of NR3A subunit-containing NMDARs to this process have only begun to be considered. Here we characterized t
Externí odkaz:
https://doaj.org/article/3644addb0ce54e74b054bece7c7b1103
Publikováno v:
Neurobiology of Learning and Memory. 138:39-53
Activity-dependent pruning of synaptic contacts plays a critical role in shaping neuronal circuitry in response to the environment during postnatal brain development. Although there is compelling evidence that shrinkage of dendritic spines coincides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dffcc87e27364d870da2e6edafe9dc6
https://doi.org/10.1016/j.nlm.2016.10.013
https://doi.org/10.1016/j.nlm.2016.10.013
Autor:
Isabel Pérez-Otaño, Masahiko Watanabe, Nobuki Nakanishi, Stuart A. Lipton, Adam C. Roberts, Benjamin D. Philpot, Rebekah Corlew, Rylan S. Larsen, Maile A. Henson, Richard J. Weinberg, Masayoshi Mishina
Recent evidence suggests that presynaptic-acting NMDA receptors (preNMDARs) are important for neocortical synaptic transmission and plasticity. We found that unique properties of the NR3A subunit enable preNMDARs to enhance spontaneous and evoked glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4404a4bfae40fd3eb224b92583e54
https://europepmc.org/articles/PMC3474337/
https://europepmc.org/articles/PMC3474337/
Various combinations of subunits assemble to form the NMDA-type glutamate receptor (NMDAR), generating diversity in its functions. Here we review roles of the unique NMDAR subunit, NR3A, which acts in a dominant-negative manner to suppress receptor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fecdc6f8d91352810f833b7c2e9c81
https://europepmc.org/articles/PMC2883719/
https://europepmc.org/articles/PMC2883719/
Downregulation of NR3A-Containing NMDARs Is Required for Synapse Maturation and Memory Consolidation
Autor:
Isabel Pérez-Otaño, William C. Wetsel, John F. Wesseling, Benjamin D. Philpot, Guoping Feng, Javier Díez-García, Donald C. Lo, Rebeca Martínez-Turrillas, Danilo Bernardo, Icíar P. López, Maile A. Henson, Dallis J. Clendeninn, Esther Picó, Laura López-Mascaraque, Rafael Luján, Adam C. Roberts, Ramona M. Rodriguiz, Thomas M. Jarrett
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
NR3A is the only NMDA receptor (NMDAR) subunit that downregulates sharply prior to the onset of sensitive periods for plasticity, yet the functional importance of this transient expression remains unknown. To investigate whether removal/replacement o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad57e49e3e70b9005af8cb55db5acc54
http://hdl.handle.net/10261/62873
http://hdl.handle.net/10261/62873
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(9)
One of the principal mechanisms of tumor immune evasion is alteration of class I MHC expression. We have identified defects contributing to down-regulation of class I MHC expression in the widely studied murine B16 melanoma and its variants B16F1, B1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14e6da794c51acf1b75235751e28197
https://pubmed.ncbi.nlm.nih.gov/12707328
https://pubmed.ncbi.nlm.nih.gov/12707328
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 168(5)
The cytotoxic activity of NK cells is regulated by class I MHC proteins. Although much has been learned about NK recognition of class I autologous targets, the mechanisms of NK self-tolerance are poorly understood. To examine the role of a nonpolymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aeaaf17fd7ba91923eb2e10aa6304f2
https://pubmed.ncbi.nlm.nih.gov/11859106
https://pubmed.ncbi.nlm.nih.gov/11859106
Autor:
Benjamin D. Philpot, Maile A. Henson, Shelikha N. Lawson, Nobuki Nakanishi, Stuart A. Lipton, Rylan S. Larsen, Isabel Pérez-Otaño
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42327 (2012)
PLoS ONE, Vol 7, Iss 8, p e42327 (2012)
Glutamatergic synapse maturation is critically dependent upon activation of NMDA-type glutamate receptors (NMDARs); however, the contributions of NR3A subunit-containing NMDARs to this process have only begun to be considered. Here we characterized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c258638005c62a723d83284b6b31acc3
https://doi.org/10.1371/journal.pone.0042327
https://doi.org/10.1371/journal.pone.0042327