Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Maiko T. Uemura"'
Autor:
Megumi Asada-Utsugi, Kengo Uemura, Takashi Ayaki, Maiko T. Uemura, Sumio Minamiyama, Ryota Hikiami, Toshifumi Morimura, Akemi Shodai, Takatoshi Ueki, Ryosuke Takahashi, Ayae Kinoshita, Makoto Urushitani
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Phosphorylated microtubule-associated protein tau (p-tau) accumulates at double-strand breaks (DSBs) in neurons. Loss of tau induces failure of DSB repair and excessive DSB accumulation, leading to aberrant p-tau aggregation and apoptotic neurons.
Externí odkaz:
https://doaj.org/article/de0adf46df324e2681f7db4538e8e628
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the perivascular space in microvessels. Originally discovered in 19th century, pericytes had drawn less attention until decades ago mainly due to lack of specific m
Externí odkaz:
https://doaj.org/article/802476aa3787484a9a99a08507a1ffeb
Autor:
Norihito Uemura, Hisashi Yagi, Maiko T. Uemura, Yusuke Hatanaka, Hodaka Yamakado, Ryosuke Takahashi
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract: Background Intraneuronal α-synuclein (α-Syn) aggregates known as Lewy bodies (LBs) and the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are the pathological hallmarks of Parkinson’s disease (PD). Braak’s h
Externí odkaz:
https://doaj.org/article/1ab91e7ad40f4ee8867a79759c584b22
Autor:
Norihito Uemura, Hisashi Yagi, Maiko T. Uemura, Yusuke Hatanaka, Hodaka Yamakado, Ryosuke Takahashi
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-1 (2019)
The original article [1] mistakenly omitted essential information regarding Fig. 1c; thus, the authors would like to note that Fig. 1c describes transmission electron microscopy of α-Syn PFFs before sonication.
Externí odkaz:
https://doaj.org/article/e99a08546c4c4a0f9c70d4c55a1ffbe2
Autor:
Maiko T. Uemura1,2, Eun Ran Suh1,2, Robinson, John L.1,2, Brunden, Kurt R.1,2, Grossman, Murray3,4, Irwin, David J.3,4,5, Lee, Virginia M.-Y.1,2, Trojanowski, John Q.1,2, Lee, Edward B.1,2 edward.lee@pennmedicine.upenn.edu, Van Deerlin, Vivianna M.1,2,6 vivianna.vandeerlin@pennmedicine.upenn.edu
Publikováno v:
Neuropathology & Applied Neurobiology. Feb2023, Vol. 49 Issue 1, p1-9. 9p.
Autor:
Tomoyuki Taguchi, Masanori Sawamura, Masashi Ikuno, Maiko T. Uemura, Norihito Uemura, Shinya Okuda, Ryosuke Takahashi, Hodaka Yamakado
Publikováno v:
Neurotherapeutics
BackgroundParkinson’s disease (PD) is the most common neurodegenerative movement disorder. Pathological features of PD include dopaminergic neuron loss in the substantia nigra pars compacta (SNpc) and intraneuronal α-Synuclein (α-Syn) inclusions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982b9604e07fe0b509648d0769c3b79d
https://doi.org/10.1007/s13311-021-01169-5
https://doi.org/10.1007/s13311-021-01169-5
Autor:
Yuri Nakamura, Yasutaka Fushimi, Takuya Hinoda, Satoshi Nakajima, Akihiko Sakata, Sachi Okuchi, Sayo Otani, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Hirotsugu Kawashima, Maiko T Uemura, Yuji Nakamoto
Publikováno v:
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.
Hemorrhage inside the mammillary bodies (MMBs) is known to be one of the findings of Wernicke encephalopathy. Brain MRI of two patients with Wernicke-Korsakoff syndrome (WKS) demonstrated high susceptibility values representing hemosiderin deposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0b61b3438ec4bfc3bbd856cfb8ffc4
https://pubmed.ncbi.nlm.nih.gov/36517008
https://pubmed.ncbi.nlm.nih.gov/36517008
Autor:
Tomoyuki Taguchi, Masanori Sawamura, Ryosuke Takahashi, Masashi Ikuno, Norihito Uemura, Jun Ueda, Junko Hara, Masato Koike, Shuichi Matsuzawa, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Shinya Okuda, Etsuro Nakanishi, Masaki Tanaka, Takashi Ayaki, Maiko T. Uemura, Mari Hondo, Masashi Yanagisawa, Yusuke Hatanaka, Omar M. A. El-Agnaf, Hodaka Yamakado
Publikováno v:
Brain. 143:249-265
Parkinson’s disease is one of the most common movement disorders and is characterized by dopaminergic cell loss and the accumulation of pathological α-synuclein, but its precise pathogenetic mechanisms remain elusive. To develop disease-modifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79227075868fc1b4496b1fb2fee932fb
https://doi.org/10.1093/brain/awz380
https://doi.org/10.1093/brain/awz380
Autor:
Maiko T. Uemura, David J. Irwin, Vivianna M. Van Deerlin, Katheryn A.Q. Cousins, Virginia M.-Y. Lee, John Q. Trojanowski, David A. Wolk, Edward B. Lee, EunRan Suh, Yan Xu, Thomas F. Tropea, Kurt R. Brunden, Sharon X. Xie, John L. Robinson, Sílvia Porta, Daniel C. Kargilis, Jennifer D. McBride, Norihito Uemura
Publikováno v:
Acta Neuropathol
Limbic-predominant age-related TDP-43 encephalopathy (LATE) is characterized by the accumulation of TAR-DNA-binding protein 43 (TDP-43) aggregates in older adults. LATE coexists with Lewy body disease (LBD) as well as other neuropathological changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebad08039290083a0c8503f81a4e390
https://europepmc.org/articles/PMC9136643/
https://europepmc.org/articles/PMC9136643/
Autor:
Maiko T. Uemura, Masashi Ikuno, Ryosuke Takahashi, Masahide Asano, Norihito Uemura, Toru Yoshihara, Jun Ueda, Hodaka Yamakado, John Q. Trojanowski
Publikováno v:
Mov Disord
Background Patients with Parkinson's disease (PD) show motor symptoms as well as various non-motor symptoms. Postmortem studies of PD have suggested that initial alpha-synuclein (α-Syn) pathology develops independently in the olfactory bulb and lowe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccaf3d2d2a08a1bbffbea5493600c602
https://europepmc.org/articles/PMC8996681/
https://europepmc.org/articles/PMC8996681/