Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Maiko Machida"'
Autor:
Maiko Machida PhD, Mayuko Ambo, Runa Mishina, Nanaka Hada, Fuhito Tachibana, Miki Yamashita PhD, Ainari Konda PhD, Kunihiko Tsuji MD, PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
Objectives: The clinical usefulness of tumor markers alpha-fetoprotein (AFP) and des-gamma carboxyprothrombin (DCP) in the early detection of hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC), including those with marker decline af
Externí odkaz:
https://doaj.org/article/aae092db3bd54448a2daf25ef6ffda4b
Autor:
Maiko Machida, Chika Yamazaki, Nao Kouda, Yousei Hanai, Hideki Sato, Ainari Konda, Yuka Yamagata, Tatsuya Itho, Haruhiko Aisaka
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background Immunotherapy with immune checkpoint inhibitors is associated with immune-related adverse events (irAEs). A positive correlation between treatment efficacy and irAEs has been reported. Clinical indicators are required for appropri
Externí odkaz:
https://doaj.org/article/a054f02cd8854a47864e432d6e73866b
Autor:
Maiko Machida, Takuji Machida, Masaki Kikuchi, Ayaka Shimizu, Syunsuke Ida, Yoshiki Tawaraya, Risa Kato, Keisuke Haramaki, Kaori Yama, Saki Shiga, Masahiko Hirafuji, Kenji Iizuka
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 3, Pp 281-285 (2022)
This study aimed to elucidate the role of nitric oxide (NO) in intestinal stem cells in methotrexate-induced ileal mucositis in rats. Methotrexate induced the mRNA expressions of the Wnt/β-catenin target genes Wnt3a, Sox9, and Lgr5 and the Wnt-antag
Externí odkaz:
https://doaj.org/article/de39600795a640d9ac9dd7c05b82e379
Publikováno v:
Women's Health Reports, Vol 3, Iss 1, Pp 267-273 (2022)
Background: The exact pathophysiology of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) is still unknown. This study aimed to investigate the concentration of 8-hydroxy-2?-deoxyguanosine (8-OHdG) in plasma in relation to the m
Externí odkaz:
https://doaj.org/article/3710c980daba4b9a94473f50490b93ed
Autor:
Akihisa Kamiya, Takuji Machida, Megumi Hirano, Maiko Machida, Saki Shiga, Naoya Hamaue, Masahiko Hirafuji, Kenji Iizuka
Publikováno v:
Journal of Pharmacological Sciences, Vol 147, Iss 3, Pp 251-259 (2021)
The effects of cyclophosphamide on 5-hydroxytryptamine (5-HT) synthesis in the intestinal tissue of rats were investigated. Rats received 120 mg/kg cyclophosphamide intraperitoneally as a single administration, and kaolin and food intake was measured
Externí odkaz:
https://doaj.org/article/8c7dacb9e4f9460abebdda1a861291f4
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 1, Pp 30-38 (2020)
The role of nitric oxide (NO) on intestinal mucosal injury induced by single or consecutive administration of methotrexate was investigated in a rodent model. Rats received methotrexate intraperitoneally either as a single administration (50 mg/kg) o
Externí odkaz:
https://doaj.org/article/a232ca00840b4ef4a72bf0ed7649e92c
Publikováno v:
Women's Health Reports, Vol 1, Iss 1, Pp 73-79 (2020)
Background: The precise pathophysiology of premenstrual syndrome (PMS) is unknown, and chronic inflammation has been implicated in PMS. However, inflammatory markers, including cytokines and C-reactive protein (CRP), have not been investigated before
Externí odkaz:
https://doaj.org/article/92bb19a6d6cd46ebbe2a60f4b8ef25e1
Autor:
Yuho Takano, Megumi Hirano, Takuji Machida, Yusuke Obara, Naoya Hamaue, Kana Fujita, Masafumi Taniguchi, Tomoko Endo, Saki Shiga, Maiko Machida, Kenji Iizuka, Masahiko Hirafuji
Publikováno v:
Journal of Pharmacological Sciences, Vol 141, Iss 1, Pp 32-40 (2019)
The role of nitric oxide (NO) in the changes in enterochromaffin cells and ileal 5-hydroxytryptamine (5-HT) content induced by a single i.p. administration of methotrexate was investigated in rats. Methotrexate significantly increased inducible NO sy
Externí odkaz:
https://doaj.org/article/8e6e6e49918c4b7f8ed07d7fa3063e81
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 3, Pp 190-193 (2017)
This study aimed to investigate the acute and chronic effect of methotrexate on the intestinal substance P metabolism after a single administration to rats. Methotrexate caused a significant increase in the number of substance P-containing cells in t
Externí odkaz:
https://doaj.org/article/173dbd914a4a4ea380423933db379c15
Autor:
Takuji Machida, Maiko Machida, Naoya Hamaue, Masahiko Hirafuji, Kenji Iizuka, Saki Shiga, Akihisa Kamiya, Megumi Hirano
Publikováno v:
Journal of Pharmacological Sciences, Vol 147, Iss 3, Pp 251-259 (2021)
The effects of cyclophosphamide on 5-hydroxytryptamine (5-HT) synthesis in the intestinal tissue of rats were investigated. Rats received 120 mg/kg cyclophosphamide intraperitoneally as a single administration, and kaolin and food intake was measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1abe066a09feef06191db53f271187b
http://www.sciencedirect.com/science/article/pii/S1347861321000748
http://www.sciencedirect.com/science/article/pii/S1347861321000748