Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maiko, Sezaki"'
Autor:
Yuji Takihara, Takumi Higaki, Tomomasa Yokomizo, Terumasa Umemoto, Kazunori Ariyoshi, Michihiro Hashimoto, Maiko Sezaki, Hitoshi Takizawa, Toshihiro Inoue, Toshio Suda, Hidenobu Mizuno
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
An intravital imaging method reveals the in vivo motile dynamics and colonization process of neonatal hematopoietic stem cells during bone marrow formation.
Externí odkaz:
https://doaj.org/article/b19549eaff0345ef8413e5e99a3aa9f9
Autor:
Maiko Sezaki, Gang Huang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Drug repurposing, the strategy to identify new therapeutic use for clinically approved drugs has attracted much attention in recent years. This strategy offers various advantages over traditional approaches to develop new drugs, including shorter dev
Externí odkaz:
https://doaj.org/article/d147947120f44ee5b8299ec167e42a23
Autor:
Takanori Matsubara, Takayuki Yanagida, Noriaki Kawaguchi, Takashi Nakano, Junichiro Yoshimoto, Maiko Sezaki, Hitoshi Takizawa, Satoshi P. Tsunoda, Shin-ichiro Horigane, Shuhei Ueda, Sayaka Takemoto-Kimura, Hideki Kandori, Akihiro Yamanaka, Takayuki Yamashita
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Scintillators emit visible luminescence when irradiated with X-rays and may enable remote optogenetic control of neurons deep in the brain. The authors inject an inorganic scintillator to activate and inhibit midbrain dopamine neurons in freely movin
Externí odkaz:
https://doaj.org/article/30586a4d7471470ab7f1c8b1080aa23f
Autor:
Takanori Matsubara, Takayuki Yanagida, Noriaki Kawaguchi, Takashi Nakano, Junichiro Yoshimoto, Maiko Sezaki, Hitoshi Takizawa, Satoshi P. Tsunoda, Shin-ichiro Horigane, Shuhei Ueda, Sayaka Takemoto-Kimura, Hideki Kandori, Akihiro Yamanaka, Takayuki Yamashita
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/76a975697486430a8dc4adfedf9f0986
Autor:
Maiko Sezaki, Yoshikazu Hayashi, Yuxin Wang, Alban Johansson, Terumasa Umemoto, Hitoshi Takizawa
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Lifelong blood production is maintained by bone marrow (BM)-residing hematopoietic stem cells (HSCs) that are defined by two special properties: multipotency and self-renewal. Since dysregulation of either may lead to a differentiation block or exten
Externí odkaz:
https://doaj.org/article/df0673ca8e6647acb0db1e3281e0e4f3
Autor:
Maiko Sezaki, Gang Huang
Publikováno v:
EMBO Molecular Medicine. 15
Drug repurposing, the strategy to identify new therapeutic use for clinically approved drugs has attracted much attention in recent years. This strategy offers various advantages over traditional approaches to develop new drugs, including shorter dev
Autor:
Maiko Sezaki, Yoshikazu Hayashi, Gaku Nakato, Yuxin Wang, Sayuri Nakata, Subinoy Biswas, Tatsuya Morishima, Md Fakruddin, Jieun Moon, Soyeon Ahn, Pilhan Kim, Yuji Miyamoto, Hideo Baba, Shinji Fukuda, Hitoshi Takizawa
Publikováno v:
The EMBO Journal. 41
Bone marrow (BM)-resident hematopoietic stem and progenitor cells (HSPCs) are often activated following bacterial insults to replenish the host hemato-immune system, but how they integrate the associated tissue damage signals to initiate distal tissu
Autor:
Motohiko Oshima, Subinoy Biswas, Atsushi Iwama, Nobukazu Okamoto, Sayuri Nakata, Nicole Pui Yu Ho, Shuhei Koide, Maiko Sezaki, Takeshi Miyamoto, Hitoshi Takizawa
Publikováno v:
Stem Cells and Development. 30:725-735
Human mesenchymal stem/stromal cells (hMSCs), when engrafted into immunodeficient mice, can form ectopic bone organs with hematopoietic stem cell (HSC) supportive functions. However, the ability to...
Autor:
Toshio Suda, Tomomasa Yokomizo, Takayoshi Matsumura, Ayako Nakamura-Ishizu, Terumasa Umemoto, Michihiro Hashimoto, Maiko Sezaki, Hitoshi Takizawa
Publikováno v:
Blood Adv
Hematopoietic stem cells (HSCs) undergo self-renewal or differentiation to sustain lifelong hematopoiesis. HSCs are preserved in quiescence with low mitochondrial activity. Recent studies indicate that autophagy contributes to HSC quiescence through