Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Maiken Lumby Henriksen"'
Autor:
Rikke Zachar, Steffen Thiel, Søren Hansen, Maiken Lumby Henriksen, Mikkel-Ole Skjoedt, Karsten Skjodt, Zohra Hamzaei, Kirsten Madsen, Lars Lund, Edith Hummler, Per Svenningsen, Boye Lagerbon Jensen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Proteolytic activation of the renal epithelial sodium channel (ENaC) is increased by aldosterone. The aldosterone-sensitive protease remains unidentified. In humans, elevated circulating aldosterone is associated with increased urinary extra
Externí odkaz:
https://doaj.org/article/9ec5c47219c44216a53700943556e8bd
Autor:
Anthony Troegeler, Geanncarlo Lugo-Villarino, Søren Hansen, Voahangy Rasolofo, Maiken Lumby Henriksen, Kenichiro Mori, Katsuki Ohtani, Carine Duval, Ingrid Mercier, Alan Bénard, Jérome Nigou, Denis Hudrisier, Nobutaka Wakamiya, Olivier Neyrolles
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132692 (2015)
Understanding the molecular components of immune recognition of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, can help designing novel strategies to combat TB. Here, we identify collectin CL-LK as a novel soluble C-type lectin able to b
Externí odkaz:
https://doaj.org/article/8152964fa72949a1be1c199f8cf0faea
Autor:
Rafael Bayarri-Olmos, Soren Hansen, Maiken Lumby Henriksen, Line Storm, Steffen Thiel, Peter Garred, Lea Munthe-Fog
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0114883 (2015)
Collectin liver 1 (CL-L1, alias CL-10) and collectin kidney 1 (CL-K1, alias CL-11), encoded by the COLEC10 and COLEC11 genes, respectively, are highly homologous soluble pattern recognition molecules in the lectin pathway of complement. These protein
Externí odkaz:
https://doaj.org/article/46b238f4f2324aa7afa5d4a4d0368852
Autor:
Maiken Lumby Henriksen, Christian Nielsen, Dennis Pedersen, Gregers Rom Andersen, Steffen Thiel, Yaseelan Palarasah, Soren Werner Karlskov Hansen
Publikováno v:
Henriksen, M L, Nielsen, C, Pedersen, D, Andersen, G R, Thiel, S, Palarasah, Y & Hansen, S W K 2022, ' Quantification of the pro-form of human complement component factor D (adipsin) ', Journal of Immunological Methods, vol. 507, pp. 113295 . https://doi.org/10.1016/j.jim.2022.113295
Factor D (also known as adipsin) is a serine protease and part of the complement system, involved in innate immune responses and effector functions of antibodies. Factor D cleaves factor B complexed with C3b, leading to the C3 convertase C3bBb. This
Autor:
Solveig Beck Nielsen, Katrine Pilely, Søren Hansen, Lars Skriver, Anette Draborg, Ejvind Mørtz, Rikke Raaen Lund, Maiken Lumby Henriksen
Publikováno v:
Pilely, K, Nielsen, S B, Draborg, A, Henriksen, M L, Hansen, S W K, Skriver, L, Mørtz, E & Lund, R R 2020, ' A novel approach to evaluate ELISA antibody coverage of host cell proteins—combining ELISA-based immunocapture and mass spectrometry ', Biotechnology Progress, vol. 36, no. 4, e2983 . https://doi.org/10.1002/btpr.2983
Biotechnology Progress
Biotechnology Progress
Monitoring host cell proteins (HCPs) is one of the most important analytical requirements in production of recombinant biopharmaceuticals to ensure product purity and patient safety. Enzyme‐linked immunosorbent assay (ELISA) is the standard method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db15fccb554b96e089f28f16676ef3b0
https://findresearcher.sdu.dk:8443/ws/files/170678160/btpr.2983.pdf
https://findresearcher.sdu.dk:8443/ws/files/170678160/btpr.2983.pdf
Autor:
Solveig Beck Nielsen, Rikke Raaen Lund, Søren Hansen, Anette Draborg, Lars Skriver, Maiken Lumby Henriksen, Ejvind Mørtz, Katrine Pilely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3bc89b029468c2b604841f35a1d8e0
https://doi.org/10.1002/btpr.2983/v2/response1
https://doi.org/10.1002/btpr.2983/v2/response1
Autor:
Jonas Heilskov Graversen, Josephine B Aagaard, Søren Hansen, Karen B Bjerrum, Maiken Lumby Henriksen
Publikováno v:
Aagaard, J B, Bjerrum, K B, Graversen, J H, Henriksen, M L & Hansen, S W K 2018, ' Novel Monoclonal Antibodies Against Native Human Collectin L1, Using the Heteromeric Complex CL-LK as Immunogen ', Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, vol. 37, no. 5, pp. 207-211 . https://doi.org/10.1089/mab.2018.0024
Collectin LK (CL-LK) is a recently described collectin complex, which upon binding to microbial glycoconjugates, activates the lectin pathway of the complement system, and thereby contributes to the removal of invading microorganisms. The complex con
Autor:
Søren Hansen, A.A. Kabiljagic, Josephine B Aagaard, J.A. Soucy, Jonas Heilskov Graversen, Karen B Bjerrum, Karsten Skjoedt, Maiken Lumby Henriksen
Publikováno v:
Bjerrum, K B, Aagaard, J B, Soucy, J A, Kabiljagic, A A, Skjoedt, K, Graversen, J H, Henriksen, M L & Hansen, S W K 2020, ' Facile generation of monoclonal antibodies suitable for conjugation ', Journal of Immunological Methods, vol. 483, 112807 . https://doi.org/10.1016/j.jim.2020.112807
Monoclonal antibodies (mAb) are unique tools in therapeutics and immunodiagnostics applications but many of these applications rely on conjugated mAbs. Whether conjugating drugs or tracers, the conjugation process, frequently taking advantage of prim
Autor:
Søren Hansen, Karen B Bjerrum, Karsten Skjoedt, Anna Lahn Sørensen, Maiken Lumby Henriksen, Josephine B Aagaard, Ole Haagen Nielsen, Jonas Heilskov Graversen, Eva Kildall Hejbøl, Henrik Daa Schrøder
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Hansen, S W K, Aagaard, J B, Bjerrum, K B, Hejbøl, E K, Nielsen, O, Schrøder, H D, Skjoedt, K, Sørensen, A L, Graversen, J H & Henriksen, M L 2018, ' CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa ', Frontiers in Immunology, vol. 9, 1757 . https://doi.org/10.3389/fimmu.2018.01757
Frontiers in Immunology
Hansen, S W K, Aagaard, J B, Bjerrum, K B, Hejbøl, E K, Nielsen, O, Schrøder, H D, Skjoedt, K, Sørensen, A L, Graversen, J H & Henriksen, M L 2018, ' CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa ', Frontiers in Immunology, vol. 9, 1757 . https://doi.org/10.3389/fimmu.2018.01757
Frontiers in Immunology
Collectin liver 1 (CL-L1, alias collectin 10) and collectin kidney 1 (CL-K1, alias collectin 11) are oligomeric pattern recognition molecules associated with the complement system, and mutations in either of their genes may lead to deficiency and dev
Autor:
Jette Brandt, Søren Hansen, Pia Hønnerup Jensen, Yaseelan Palarasah, Jean-Piere Andrieu, Christian Nielsen, Thomas J. D. Jørgensen, Maiken Lumby Henriksen, Nicole M. Thielens, Uffe Holmskov
Publikováno v:
Henriksen, M L, Brandt, J, Andrieu, J-P, Nielsen, C, Jensen, P H, Holmskov, U, Jørgensen, T J D, Palarasah, Y, Thielens, N M & Hansen, S 2013, ' Heteromeric Complexes of Native Collectin Kidney 1 and Collectin Liver 1 Are Found in the Circulation with MASPs and Activate the Complement System ', Journal of Immunology, vol. 191, no. 12, pp. 6117-6127 . https://doi.org/10.4049/jimmunol.1302121
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, pp.6117-27
Journal of Immunology, 2013, pp.6117-27
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, pp.6117-27
Journal of Immunology, 2013, pp.6117-27
The complement system is an important part of the innate immune system. The complement cascade may be initiated downstream of the lectin activation pathway upon binding of mannan-binding lectin, ficolins, or collectin kidney 1 (CL-K1, alias CL-11) to