Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maikel Herbrink"'
Autor:
Merel van Nuland, Anne-Fleur H. Lobbezoo, Ewoudt M.W. van de Garde, Maikel Herbrink, Inger van Heijl, Tim Bognàr, Jeroen P.A. Houwen, Marloes Dekens, Demi Wannet, Toine Egberts, Paul D. van der Linden
Publikováno v:
Exploratory Research in Clinical and Social Pharmacy, Vol 15, Iss , Pp 100464- (2024)
Background: The advent of Large Language Models (LLMs) such as ChatGPT introduces opportunities within the medical field. Nonetheless, use of LLM poses a risk when healthcare practitioners and patients present clinical questions to these programs wit
Externí odkaz:
https://doaj.org/article/0dec1526e8624f9b9b3ec871c3215346
Publikováno v:
International Journal of Pharmaceutics, 529(1-2), 294. Elsevier bedrijfsinformatie b.v.
The tyrosine kinase inhibitor nilotinib has a very low aqueous solubility and a low and variable oral bioavailability. A pharmaceutical formulation with an improved solubility may enhance the bioavailability and reduce the variability thereof and of
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 130:1491-1499
The currently marketed formulation of pazopanib hydrochloride has a poor bioavailability and pharmacokinetic profile. An alternative formulation of the drug might have an improved performance. Knowledge about the thermal behavior of the drug may be i
Autor:
Alwin D. R. Huitema, Hilde Rosing, Maikel Herbrink, Bastiaan Nuijen, Jan H.M. Schellens, N. de Vries, Jos H. Beijnen
Publikováno v:
Biomedical Chromatography, 32(4). John Wiley and Sons Ltd
To support therapeutic drug monitoring of patients with cancer, a fast and accurate method for simultaneous quantification of the registered anticancer drugs afatinib, axitinib, ceritinib, crizotinib, dabrafenib, enzalutamide, regorafenib and trameti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856123b8dc7a08bcdfbecf31e21d7cfe
https://dspace.library.uu.nl/handle/1874/366881
https://dspace.library.uu.nl/handle/1874/366881
Autor:
Peter Blanken, Amin Janmohamed, Vincent M. Hendriks, Alwin D. R. Huitema, Bastiaan Nuijen, Jos H. Beijnen, Maikel Herbrink, Masha Nuijten, Wim van den Brink
Publikováno v:
Journal of Clinical Psychopharmacology, 38(3), 212-217
Journal of Clinical Psychopharmacology, 544(1), 181. Lippincott Williams and Wilkins
Journal of clinical psychopharmacology, 38(3), 212-217. Lippincott Williams and Wilkins
Journal of Clinical Psychopharmacology, 544(1), 181. Lippincott Williams and Wilkins
Journal of clinical psychopharmacology, 38(3), 212-217. Lippincott Williams and Wilkins
Introduction Research has shown that sustained-release (SR) dexamphetamine is a promising agonist treatment for cocaine dependence. However, little is known about the pharmacokinetics (PKs) of SR oral dexamphetamine. This study examined the PKs of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb84e83f8e860c509fecffa6e08b3437
https://dspace.library.uu.nl/handle/1874/376985
https://dspace.library.uu.nl/handle/1874/376985
Publikováno v:
Pharmaceutical Research, 34(9), 1751. Springer New York LLC
Recent literature reviews and registration documents covering novel Signal Transduction Inhibitors in the treatment of cancer paint a picture of inefficiency and variability, where formulation improvements could be valuable. In this article, we discu