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pro vyhledávání: '"Maikel González-Matos"'
Autor:
Jorge González-Bacerio, Maikel Izquierdo, Mirtha Elisa Aguado, Ana C. Varela, Maikel González-Matos, Maday Alonso del Rivero
Publikováno v:
Microbial Cell, Vol 8, Iss 10, Pp 239-246 (2021)
Several microbial metalo-aminopeptidases are emerging as novel targets for the treatment of human infectious diseases. Some of them are well validated as targets and some are not; some are essential enzymes and others are important for virulence and
Externí odkaz:
https://doaj.org/article/6d46b80827814f7c83550a392acbfd4b
Autor:
Jorge González-Bacerio, Mirtha Elisa Aguado, Maikel Izquierdo, Maikel González-Matos, Ana C. Varela, Yanira Méndez, Maday Alonso del Rivero, Daniel G. Rivera
Publikováno v:
Current Drug Targets. 24:416-461
Background: Parasitic human infectious diseases are a worldwide health problem due to the increased resistance to conventional drugs. For this reason, the identification of novel molecular targets and the discovery of new chemotherapeutic agents are
Autor:
Maikel González-Matos, Ana C. Varela, Maday Alonso del Rivero, Mirtha Elisa Aguado, Jorge González-Bacerio, Maikel Izquierdo
Publikováno v:
Microbial Cell
Microbial Cell, Vol 8, Iss 10, Pp 239-246 (2021)
Microbial Cell, Vol 8, Iss 10, Pp 239-246 (2021)
Several microbial metalo-aminopeptidases are emerging as novel targets for the treatment of human infectious diseases. Some of them are well validated as targets and some are not; some are essential enzymes and others are important for virulence and
Autor:
Maikel González-Matos, Juan F. Quintana, Jorge González-Bacerio, Maikel Izquierdo, Mirtha Elisa Aguado, Mark C. Field
Publikováno v:
Protein expression and purification. 183
The Leishmania major leucyl-aminopeptidase (LAPLm), a member of the M17 family of proteases, is a potential drug target for treatment of leishmaniasis. To better characterize enzyme properties, recombinant LAPLm (rLAPLm) was expressed in Escherichia