Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maikel D. Wouters"'
Autor:
Valentina Iadevaia, Alexander Kanitz, Maikel D. Wouters, André P. Gerber, Ana M. Matia-González, Emma Laing
Publikováno v:
RNA Biology
Post-transcriptional control of gene expression is mediated via RNA-binding proteins (RBPs) that interact with mRNAs in a combinatorial fashion. While recent global RNA interactome capture experiments expanded the repertoire of cellular RBPs quiet dr
Autor:
Steven Van Laere, Wilfred F. J. van IJcken, Ron H.J. Mathijssen, Marijn T.M. van Jaarsveld, Maikel D. Wouters, Erik A.C. Wiemer, Antonius W. M. Boersma, John W.M. Martens, Jan H.J. Hoeijmakers, Joris Pothof, Marcel Smid
Publikováno v:
Molecular Oncology, 8(3), 458-468. John Wiley & Sons Ltd.
The DNA damage response (DDR) is activated upon DNA damage and prevents accumulation of mutations and chromosomal rearrangements, both driving carcinogenesis. Tumor cells often have defects in the DDR, which in combination with continuous cell prolif
Publikováno v:
Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis, 717(1-2), 54-66. Elsevier
Many carcinogenic agents such as ultra-violet light from the sun and various natural and man-made chemicals act by damaging the DNA. To deal with these potentially detrimental effects of DNA damage, cells induce a complex DNA damage response (DDR) th
Autor:
Erik A.C. Wiemer, Patricia F. van Kuijk, Antonius W. M. Boersma, Marijn T.M. van Jaarsveld, Maikel D. Wouters, Jaap Verweij, Joris Pothof
Publikováno v:
Cancer Research. 71:4952-4952
Tumor cells are often characterized by a rapid cell division rate and defects in their DNA damage response, which is exploited in the clinic by the use of DNA damaging anticancer agents. Platinum-based chemotherapy (e.g. cisplatin) is used for the tr