Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maikel Castellano-Pozo"'
Autor:
Maikel Castellano-Pozo, Georgios Sioutas, Consuelo Barroso, Josh P Prince, Pablo Lopez-Jimenez, Joseph Davy, Angel-Luis Jaso-Tamame, Oliver Crawley, Nan Shao, Jesus Page, Enrique Martinez-Perez
Publikováno v:
eLife, Vol 12 (2023)
The cohesin complex plays essential roles in chromosome segregation, 3D genome organisation, and DNA damage repair through its ability to modify DNA topology. In higher eukaryotes, meiotic chromosome function, and therefore fertility, requires cohesi
Externí odkaz:
https://doaj.org/article/1235e182b1454f73a8f6a72952cf9905
Publikováno v:
Biology, Vol 12, Iss 5, p 671 (2023)
The integrity of the genome is crucial for the survival of all living organisms. However, genomes need to adapt to survive certain pressures, and for this purpose use several mechanisms to diversify. Chromosomal instability (CIN) is one of the main m
Externí odkaz:
https://doaj.org/article/121be11d8d1d4c6abcf3470aa166c183
Autor:
Maikel Castellano-Pozo, Sarai Pacheco, Georgios Sioutas, Angel Luis Jaso-Tamame, Marian H. Dore, Mohammad M. Karimi, Enrique Martinez-Perez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a m
Externí odkaz:
https://doaj.org/article/ca7beece05774737bac58f1c2cc21c92
Autor:
Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R Brooks, R Elwyn Isaac, Simon J Boulton, Enrique Martinez-Perez
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1010025 (2022)
Genotoxic stress during DNA replication constitutes a serious threat to genome integrity and causes human diseases. Defects at different steps of DNA metabolism are known to induce replication stress, but the contribution of other aspects of cellular
Externí odkaz:
https://doaj.org/article/a96ac9391b0141f5855e9de298dde95f
Autor:
Oliver Crawley, Consuelo Barroso, Sarah Testori, Nuria Ferrandiz, Nicola Silva, Maikel Castellano-Pozo, Angel Luis Jaso-Tamame, Enrique Martinez-Perez
Publikováno v:
eLife, Vol 5 (2016)
Wapl induces cohesin dissociation from DNA throughout the mitotic cell cycle, modulating sister chromatid cohesion and higher-order chromatin structure. Cohesin complexes containing meiosis-specific kleisin subunits govern most aspects of meiotic chr
Externí odkaz:
https://doaj.org/article/4b4e7c5ddc494e91840a5f486dd22405
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160138 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0052447.].
Externí odkaz:
https://doaj.org/article/0ecc54085fd248b9863de74f762e3d97
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52447 (2012)
THO is a conserved eukaryotic complex involved in mRNP biogenesis and RNA export that plays an important role in preventing transcription- and RNA-mediated genome instability in mitosis and meiosis. In mammals THO is essential for embryogenesis, whic
Externí odkaz:
https://doaj.org/article/ccb46ccdd400408b98343beb202759d5
En la educación universitaria es muy importante la incorporación de técnicas de enseñanza y aprendizaje que faciliten el desarrollo de competencias vitales para el trayecto académico y profesional de los estudiantes. La aplicación de conceptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbeb9b64d29edb83ed74ac167c50a7e
Autor:
Amador Romero-Franco, Cintia Checa-Rodríguez, Maikel Castellano-Pozo, Hector Miras, Amadeo Wals, Pablo Huertas
The maintenance of genomic stability is essential for cellular and organismal survival and fitness. Thus, when DNA gets damaged, is essential to repair it in the most accurate fashion. Among different DNA lesions, DNA double strand breaks are special
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2947bc2ec118bfbfbd6198583ad22a40
https://doi.org/10.1101/2023.01.22.524239
https://doi.org/10.1101/2023.01.22.524239
Autor:
Maikel Castellano-Pozo, Georgios Sioutas, Consuelo Barroso, Pablo Lopez-Jimenez, Angel Luis Jaso-Tamame, Oliver Crawley, Nan Shao, Jesus Page, Enrique Martinez-Perez
The cohesin complex plays essential roles in chromosome segregation, 3D genome organisation, and DNA damage repair through its ability to modify DNA topology. In higher eukaryotes, meiotic chromosome function, and therefore fertility, requires cohesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7083e0f186f40cc7871c3a9e1aa5ec2d
https://doi.org/10.1101/2022.10.12.511771
https://doi.org/10.1101/2022.10.12.511771