Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Maikel Acosta‐Zaldívar"'
Autor:
Maikel Acosta-Zaldívar, Wanjun Qi, Abhishek Mishra, Udita Roy, William R King, Yuping Li, Jana Patton-Vogt, Matthew Z Anderson, Julia R Köhler
Publikováno v:
PLoS Genetics, Vol 20, Iss 8, p e1011156 (2024)
Phosphorus is essential in all cells' structural, metabolic and regulatory functions. For fungal cells that import inorganic phosphate (Pi) up a steep concentration gradient, surface Pi transporters are critical capacitators of growth. Fungi must dep
Externí odkaz:
https://doaj.org/article/3a2f81f21d8a4df7854309ca931adb93
Autor:
William R. King, Maikel Acosta-Zaldívar, Wanjun Qi, Nicholas Cherico, Lauren Cooke, Julia R. Köhler, Jana Patton-Vogt
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTThe fungal pathogen Candida albicans must acquire phosphate to colonize, infect, and proliferate in the human host. C. albicans has four inorganic phosphate (Pi) transporters, Pho84 being the major high-affinity transporter; its cells can als
Externí odkaz:
https://doaj.org/article/43e424979ee442bfbfcb00370c130264
Autor:
Xionghui Ding, Hiroto Kambara, Rongxia Guo, Apurva Kanneganti, Maikel Acosta-Zaldívar, Jiajia Li, Fei Liu, Ting Bei, Wanjun Qi, Xuemei Xie, Wenli Han, Ningning Liu, Cunling Zhang, Xiaoyu Zhang, Hongbo Yu, Li Zhao, Fengxia Ma, Julia R. Köhler, Hongbo R. Luo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Inflammasome signalling has been shown to protect Candida albicans during infection and as such limits inflammasome inhibitors in this context. Here the authors implicate Gasdermin D in C.ablicans immune evasion and suggests its targeting therapeutic
Externí odkaz:
https://doaj.org/article/e7787a117ee6429d98db5af480b18015
Autor:
Ángel L. Álvarez, Alberto García-Manso, Kevin P. Dalton, José M. Martín-Alonso, Inés Nicieza, Ana Podadera, Maikel Acosta-Zaldívar, Daniel de Llano, Francisco Parra
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Most caliciviruses are refractory to replication in cell culture and only a few members of the family propagate in vitro. Rabbit vesivirus (RaV) is unique due to its ability to grow to high titers in several animal and human cell lines. This outstand
Externí odkaz:
https://doaj.org/article/3da3af5cbcd74a0f89d4c7f6b4da7125
Autor:
Ning-Ning Liu, Maikel Acosta-Zaldívar, Wanjun Qi, Joann Diray-Arce, Louise A. Walker, Theodore J. Kottom, Rachel Kelly, Min Yuan, John M. Asara, Jessica Ann Lasky-Su, Ofer Levy, Andrew H. Limper, Neil A. R. Gow, Julia R. Köhler
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The Candida albicans high-affinity phosphate transporter Pho84 is required for normal Target of Rapamycin (TOR) signaling, oxidative stress resistance, and virulence of this fungal pathogen. It also contributes to C. albicans’ tolerance of
Externí odkaz:
https://doaj.org/article/dd3ae8e11a964f948c0d20db254e5bb3
Publikováno v:
Journal of Fungi, Vol 6, Iss 2, p 40 (2020)
Candida species are the most commonly isolated invasive human fungal pathogens. A role for phosphate acquisition in their growth, resistance against host immune cells, and tolerance of important antifungal medications is becoming apparent. Phosphorus
Externí odkaz:
https://doaj.org/article/f4c256f284234af6be8fba991e875bd4
Autor:
Ning-Ning Liu, Priya Uppuluri, Achille Broggi, Angelique Besold, Kicki Ryman, Hiroto Kambara, Norma Solis, Viola Lorenz, Wanjun Qi, Maikel Acosta-Zaldívar, S Noushin Emami, Bin Bao, Dingding An, Francisco A Bonilla, Martha Sola-Visner, Scott G Filler, Hongbo R Luo, Ylva Engström, Per Olof Ljungdahl, Valeria C Culotta, Ivan Zanoni, Jose L Lopez-Ribot, Julia R Köhler
Publikováno v:
PLoS Pathogens, Vol 14, Iss 7, p e1007076 (2018)
Phosphate is an essential macronutrient required for cell growth and division. Pho84 is the major high-affinity cell-surface phosphate importer of Saccharomyces cerevisiae and a crucial element in the phosphate homeostatic system of this model yeast.
Externí odkaz:
https://doaj.org/article/c1979e604e4a4ae38cfb36cc297e8e70
Autor:
Patricia Davenport, Hsuan‐Hao Fan, Emily Nolton, Henry A. Feldman, Viola Lorenz, Jorge Canas, Maikel Acosta‐Zaldívar, William Yakah, Connie Arthur, Camilia Martin, Sean Stowell, Julia Koehler, Donald Mager, Martha Sola‐Visner
Publikováno v:
Transfusion. 62:1177-1187
Platelet transfusions (PTxs) are often given to septic preterm neonates at high platelet count thresholds in an attempt to reduce bleeding risk. However, the largest randomized controlled trial (RCT) of neonatal transfusion thresholds found higher mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11927dbaecbb4902d801f9c1ff8e5b57
https://doi.org/10.1111/trf.16895
https://doi.org/10.1111/trf.16895
Autor:
Hongbo Yu, Fei Liu, Hiroto Kambara, Xuemei Xie, Maikel Acosta-Zaldívar, Cunling Zhang, Julia R. Köhler, Jiajia Li, Hongbo R. Luo, Rongxia Guo, Ning-Ning Liu, Ting Bei, Fengxia Ma, Li Zhao, Xionghui Ding, Wenli Han, Xiaoyu Zhang, Wanjun Qi, Apurva Kanneganti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Nature Communications
Nature Communications
Candida albicans is the most common cause of fungal sepsis. Inhibition of inflammasome activity confers resistance to polymicrobial and LPS-induced sepsis; however, inflammasome signaling appears to protect against C. albicans infection, so inflammas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86278577f1aa0afeff9c2377171d33b4
https://doaj.org/article/e7787a117ee6429d98db5af480b18015
https://doaj.org/article/e7787a117ee6429d98db5af480b18015
Autor:
Hiroto Kambara, Xionghui Ding, Apurva Kanneganti, Maikel Acosta-Zaldívar, Ting Bei, Wanjun Qi, Xuemei Xie, Wenli Han, Ningning Liu, Cunling Zhang, Xiaoyu Zhang, Hongbo Yu, Li Zhao, Yong Jiang, Fengxia Ma, Julia R. Köhler, Hongbo Luo
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a9f9f72b280f96702f0515a32f32cd4
https://doi.org/10.2139/ssrn.3719310
https://doi.org/10.2139/ssrn.3719310