Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maike Lichtenberg"'
Publikováno v:
Cell Death & Disease
Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common known cause of Parkinson's disease (PD). The clinical features of LRRK2 PD are indistinguishable from idiopathic PD, with accumulation of α-synuclein and/or tau and/or ubiquitin in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9216fab44be7d2b9eb7afd5828c5db0a
Autor:
Sara Imarisio, Shinji Saiki, Maike Lichtenberg, Fiona M. Menzies, Vojo Deretic, David C. Rubinsztein, Marie Futter, Esteban A. Roberts, Sovan Sarkar, Viktor I. Korolchuk, Cahir J. O'Kane, Farah H. Siddiqi, Luca Jahreiss
Publikováno v:
Nature cell biology
Mammalian target of rapamycin (mTOR) signalling and macroautophagy (henceforth autophagy) regulate numerous pathological and physiological processes including cellular responses to altered nutrient levels. However, the mechanisms regulating mTOR and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9169a39bf0a389947dc8441122e8438e
http://europepmc.org/articles/PMC3071334
http://europepmc.org/articles/PMC3071334
Autor:
Sovan Sarkar, Viktor I. Korolchuk, Brinda Ravikumar, Ashley R. Winslow, Janet E. Davies, Dunecan Massey, Shouqing Luo, Usha Narayanan, Zeyn W. Green-Thompson, Moisés García-Arencibia, Benjamin R. Underwood, Farah H. Siddiqi, Maike Lichtenberg, Maria Jimenez-Sanchez, Fiona M. Menzies, David C. Rubinsztein, Kevin Moreau, Maurizio Renna, Marie Futter
Publikováno v:
Physiological Reviews. 90:1383-1435
(Macro)autophagy is a bulk degradation process that mediates the clearance of long-lived proteins and organelles. Autophagy is initiated by double-membraned structures, which engulf portions of cytoplasm. The resulting autophagosomes ultimately fuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316b80a8b46b28f6911271c0c17edd0c
https://doi.org/10.1152/physrev.00030.2009
https://doi.org/10.1152/physrev.00030.2009
Autor:
Chien-Wen Chen, Abraham Acevedo-Arozena, Fiona M. Menzies, David E. Gordon, Cahir J. O'Kane, Steve D.M. Brown, Ashley R. Winslow, Brinda Ravikumar, David C. Rubinsztein, Maike Lichtenberg, Andrew A. Peden, Sara Imarisio, Silvia Corrochano
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology; Vol 190
The Journal of Cell Biology; Vol 190
α-Synuclein impairs autophagosome formation and mislocalizes Atg9 by inhibiting Rab1a.
Parkinson’s disease (PD) is characterized pathologically by intraneuronal inclusions called Lewy bodies, largely comprised of α-synuclein. Multiplication
Parkinson’s disease (PD) is characterized pathologically by intraneuronal inclusions called Lewy bodies, largely comprised of α-synuclein. Multiplication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7ab64c35d25b81fada0ee81d3d7a6e
https://pubmed.ncbi.nlm.nih.gov/20855506
https://pubmed.ncbi.nlm.nih.gov/20855506
Autor:
David C. Rubinsztein, Fiona M. Menzies, Sovan Sarkar, Ashley R. Winslow, Usha Narayanan, Maike Lichtenberg, Luca Jahreiss, Maria Jimenez-Sanchez, Dunecan Massey, Benjamin R. Underwood, Shouqing Luo, Viktor I. Korolchuk, Brinda Ravikumar, Maurizio Renna, Marie Futter
Autophagy refers to a set of non-specific bulk degradation processes in which cells deliver cytoplasmic substrates for lysosomal degradation. Types of autophagy include macroautophagy, chaperone-mediated autophagy and microautophagy. Chaperone-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c74c7c3c3921f79814efe4c8c3ac0e
http://hdl.handle.net/11386/2036169
http://hdl.handle.net/11386/2036169
Autor:
Clarissa Gerhäuser, Gerlinde Pappa, Helmut Bartsch, Jessica Barillari, Maike Lichtenberg, Renato Iori
Publikováno v:
Mutation research. 599(1-2)
The isothiocyanates sulforaphane and PEITC (beta-phenethyl isothiocyanate) as well as the indoles indole-3-carbinol and its condensation product 3,3'-diindolylmethane are known to inhibit cancer cell proliferation and induce apoptosis. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d0b8d45bf1c72004457d965d9143f3
https://pubmed.ncbi.nlm.nih.gov/16500682
https://pubmed.ncbi.nlm.nih.gov/16500682
Autor:
Ashley R. Winslow, Chien-Wen Chen, Silvia Corrochano, Abraham Acevedo-Arozena, David E. Gordon, Andrew A. Peden, Maike Lichtenberg, Fiona M. Menzies, Brinda Ravikumar, Sara Imarisio, Steve Brown, Cahir J. O'Kane, David C. Rubinsztein
Publikováno v:
The Journal of Experimental Medicine. 207:i29-i29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be80bc8e28243153997698e02e441dfd
https://doi.org/10.1084/jem20710oia29
https://doi.org/10.1084/jem20710oia29