Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maike Jaworski"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89270 (2014)
The immune system and iron availability are intimately linked as appropriate iron supply is needed for cell proliferation, while excess iron, as observed in hemochromatosis, may reduce subsets of lymphocytes. We have tested the effects of a ferritin
Externí odkaz:
https://doaj.org/article/ba2833c096394994b75356945d848b06
Autor:
Sebastian Bunk, Martin Hofmann, Gabriele Pszolla, Meike Hutt, Felix Unverdorben, Frank Schwoebel, Nadine Aschmoneit, Claudia Wagner, Maike Jaworski, Christoph Schraeder, Heiko Schuster, Sarah Missel, Toni Weinschenk, Dominik Maurer, Carsten Reinhardt
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34190b24ee76bd453e47e8de8297bc7a
https://doi.org/10.1136/jitc-2022-sitc2022.1319
https://doi.org/10.1136/jitc-2022-sitc2022.1319
Autor:
Gloria B. Kim, Jens Fritsche, Sebastian Bunk, Andrea Mahr, Felix Unverdorben, Kevin Tosh, Hong Kong, Colby R. Maldini, Chui Lau, Sriram Srivatsa, Shuguang Jiang, Joshua Glover, Derek Dopkin, Carolyn X. Zhang, Heiko Schuster, Daniel J. Kowalewski, Valentina Goldfinger, Martina Ott, David Fuhrmann, Maike Baues, Hans Boesmueller, Christoph Schraeder, Gisela Schimmack, Colette Song, Franziska Hoffgaard, Michael Roemer, Chih-Chiang Tsou, Martin Hofmann, Thomas Treiber, Meike Hutt, Leonie Alten, Maike Jaworski, Amir Alpert, Sarah Missel, Carsten Reinhardt, Harpreet Singh, Oliver Schoor, Steffen Walter, Claudia Wagner, Dominik Maurer, Toni Weinschenk, James L. Riley
Publikováno v:
Sci Transl Med
T cell receptor (TCR)–based immunotherapy has emerged as a promising therapeutic approach for the treatment of patients with solid cancers. Identifying peptide–human leukocyte antigen (pHLA) complexes highly presented on tumors and rarely express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f6e898b6a4776378ef2a9476f7dac1
https://pubmed.ncbi.nlm.nih.gov/36516272
https://pubmed.ncbi.nlm.nih.gov/36516272
Autor:
Sebastian Bunk, Martin Hofmann, Gabriele Pszolla, Meike Hutt, Frank Schwöbel, Felix Unverdorben, Nadine Aschmoneit, Claudia Wagner, Maike Jaworski, Heiko Schuster, Florian Schwoerer, Christoph Schraeder, Oliver Schoor, Sarah Missel, Toni Weinschenk, Dominik Maurer, Carsten Reinhardt
Publikováno v:
Blood. 140:9089-9090
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7740dec0d52b05e6090141f4e02d38f2
https://doi.org/10.1182/blood-2022-165937
https://doi.org/10.1182/blood-2022-165937
Autor:
Margot Thome, Maike Jaworski
Publikováno v:
Cellular and Molecular Life Sciences
Cell. Mol. Life Sci.
Cell. Mol. Life Sci.
The paracaspase MALT1 has a central role in the activation of lymphocytes and other immune cells including myeloid cells, mast cells and NK cells. MALT1 activity is required not only for the immune response, but also for the development of natural Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6e22818565f530bbbd9b2443d5c90d
https://doi.org/10.1007/s00018-015-2059-z
https://doi.org/10.1007/s00018-015-2059-z
Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity
Autor:
Maike Jaworski, Margot Thome, Sanjiv A. Luther, Olivier Gaide, Mai Perroud, Ben J Marsland, Stéphanie Favre, Werner Held, Dela Golshayan, Jasmine Gehrig
Publikováno v:
The EMBO Journal
EMBO Journal, vol. 33, no. 23, pp. 2765-2781
EMBO J.
ResearcherID
The EMBO journal
EMBO Journal, vol. 33, no. 23, pp. 2765-2781
EMBO J.
ResearcherID
The EMBO journal
The protease activity of the paracaspase Malt1 has recently gained interest as a drug target for immunomodulation and the treatment of diffuse large B-cell lymphomas. To address the consequences of Malt1 protease inactivation on the immune response i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442b12949ec5c39001f8809c166f5b7d
https://doi.org/10.15252/embj.201488987
https://doi.org/10.15252/embj.201488987
Autor:
Georg Lenz, Christiane Pelzer, Montserrat Guzzardi, Chantal Décaillet, Bernd Dörken, Margot Thome, Stephan Hailfinger, Maike Jaworski, Peter Lenz, Jean-Enno Charton, Hendrik Nogai, Michael Grau, Katrin Cabalzar
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14596-14601
The protease activity of the paracaspase Malt1 contributes to antigen receptor-mediated lymphocyte activation and lymphomagenesis. Malt1 activity is required for optimal NF-κB activation, but little is known about the responsible substrate(s). Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f7c37e997b3f63cd546f7424e39a64
https://doi.org/10.1073/pnas.1105020108
https://doi.org/10.1073/pnas.1105020108
Publikováno v:
Biomaterials. 32:321-329
In the bone marrow, specialized microenvironments, called niches, regulate hematopoietic stem cell (HSC) maintenance and function through a complex crosstalk between different cell types. Although in vivo studies have been instrumental to elucidate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d8f439b8f56fdab260f920a1d06a78
https://doi.org/10.1016/j.biomaterials.2010.09.041
https://doi.org/10.1016/j.biomaterials.2010.09.041
Autor:
Zhenyu Ju, Maike Jaworski, Christoph Klein, Hong Jiang, Chozhavendan Rathinam, K. Lenhard Rudolph, Andreas Trumpp, Anne Gompf
Publikováno v:
Nature Medicine. 13:742-747
Cell-intrinsic checkpoints limit the proliferative capacity of primary cells in response to telomere dysfunction. It is not known, however, whether telomere dysfunction contributes to cell-extrinsic alterations that impair stem cell function and orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21840e5b1811426e8b4bc777a9af89ac
https://doi.org/10.1038/nm1578
https://doi.org/10.1038/nm1578
Autor:
Anne Wilson, Elisa Laurenti, Gabriela M. Oser, Christelle Adolphe, H. Robson MacDonald, William Blanco-Bose, Andreas Trumpp, Maike Jaworski, Marieke A.G. Essers
Publikováno v:
Annals of the New York Academy of Sciences. 1106:64-75
In the mouse, over the last 20 years, a set of cell-surface markers and activities have been identified, enabling the isolation of bone marrow (BM) populations highly enriched in hematopoietic stem cells (HSCs). These HSCs have the ability to generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d82a623eed339240e6dd58e57152eeb
https://doi.org/10.1196/annals.1392.021
https://doi.org/10.1196/annals.1392.021