Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maike A. Roth"'
Autor:
Jake M. Bieber, Laura E. Sanman, Xiaoxiao Sun, Heinz Hammerlindl, Feng Bao, Maike A. Roth, Megan L. Koleske, Liusheng Huang, Fran Aweeka, Lani F. Wu, Steven J. Altschuler
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Bieber et al use intestinal monolayers derived from fresh murine crypts as a model system to study drug toxicity. Testing 48 oncology drugs with known gastrointestinal toxicity as a proof of concept, they discover differential responses in cells from
Externí odkaz:
https://doaj.org/article/41ed1bb6411d4d969ca1025fa3f04d80
Autor:
Michael Ramirez, Satwik Rajaram, Robert J. Steininger, Daria Osipchuk, Maike A. Roth, Leanna S. Morinishi, Louise Evans, Weiyue Ji, Chien-Hsiang Hsu, Kevin Thurley, Shuguang Wei, Anwu Zhou, Prasad R. Koduru, Bruce A. Posner, Lani F. Wu, Steven J. Altschuler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Cancer cells that survive initial drug treatment can persist in the presence of drugs. Here, the authors generate persister cells that are resistant to the EGFR tyrosine kinase inhibitor erlotinib and show by single cell analysis that multiple mechan
Externí odkaz:
https://doaj.org/article/bd1a3c50ad1a402d9bff233756a1c84e
Autor:
Scott R. VandenBerg, Chloe E. Atreya, Satwik Rajaram, Julia Malato, Steven J. Altschuler, Maike A. Roth, Lani F. Wu, Byron Hann
Publikováno v:
Scientific data, vol 6, iss 1
Scientific Data
Scientific Data, Vol 6, Iss 1, Pp 1-13 (2019)
Scientific Data
Scientific Data, Vol 6, Iss 1, Pp 1-13 (2019)
Patient-derived xenografts (PDXs) are an essential pre-clinical resource for investigating tumor biology. However, cellular heterogeneity within and across PDX tumors can strongly impact the interpretation of PDX studies. Here, we generated a multi-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4f3d6bd0ba98f13c1f95ad2741b324
https://escholarship.org/uc/item/4ns985fx
https://escholarship.org/uc/item/4ns985fx
Autor:
Shuguang Wei, Kevin Thurley, Steven J. Altschuler, Weiyue Ji, Anwu Zhou, Maike A. Roth, Chien Hsiang Hsu, Robert J. Steininger, Prasad Koduru, Michael Ramirez, Bruce A. Posner, Daria Osipchuk, Louise Evans, Satwik Rajaram, Lani F. Wu, Leanna S. Morinishi
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Cancer therapy has traditionally focused on eliminating fast-growing populations of cells. Yet, an increasing body of evidence suggests that small subpopulations of cancer cells can evade strong selective drug pressure by entering a ‘persister' sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9084ebf3ef8e1edee11cd8680b6741fb
http://europepmc.org/articles/PMC4762880
http://europepmc.org/articles/PMC4762880