Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Maika Malig"'
Autor:
Michael J. Dennis, Dean C. Pavlick, Alec Kacew, Michael Wotman, Laura E. MacConaill, Stephanie M. Jones, Kathleen L. Pfaff, Scott J. Rodig, Stephen Eacker, Maika Malig, Emily Reister, David Piccioni, Santosh Kesari, Kartik Sehgal, Robert I. Haddad, Ezra Cohen, Marshall R. Posner, Ida Deichaite, Glenn J. Hanna
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Brain metastasis (BM) is a rare but severe complication of head and neck squamous cell carcinoma (HNSCC), with limited knowledge of molecular characteristics and immunogenicity. Methods We analyzed 61 cases of HNSCC-BM from three
Externí odkaz:
https://doaj.org/article/c494f43336d14d3082d8e50a20f138b9
Autor:
Stuart Cantsilieris, Susan M. Sunkin, Matthew E. Johnson, Fabio Anaclerio, John Huddleston, Carl Baker, Max L. Dougherty, Jason G. Underwood, Arvis Sulovari, PingHsun Hsieh, Yafei Mao, Claudia Rita Catacchio, Maika Malig, AnneMarie E. Welch, Melanie Sorensen, Katherine M. Munson, Weihong Jiang, Santhosh Girirajan, Mario Ventura, Bruce T. Lamb, Ronald A. Conlon, Evan E. Eichler
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-35 (2020)
Abstract Background The complex interspersed pattern of segmental duplications in humans is responsible for rearrangements associated with neurodevelopmental disease, including the emergence of novel genes important in human brain evolution. We inves
Externí odkaz:
https://doaj.org/article/c298b2c7af2145a8892cd82025ceb851
Autor:
Nima Rafati, Lisa S. Andersson, Sofia Mikko, Chungang Feng, Terje Raudsepp, Jessica Pettersson, Jan Janecka, Ove Wattle, Adam Ameur, Gunilla Thyreen, John Eberth, John Huddleston, Maika Malig, Ernest Bailey, Evan E. Eichler, Göran Dalin, Bhanu Chowdary, Leif Andersson, Gabriella Lindgren, Carl-Johan Rubin
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 7, Pp 2213-2223 (2016)
Skeletal atavism in Shetland ponies is a heritable disorder characterized by abnormal growth of the ulna and fibula that extend the carpal and tarsal joints, respectively. This causes abnormal skeletal structure and impaired movements, and affected f
Externí odkaz:
https://doaj.org/article/ba30170570d34bc9a0a01fe3f9f48c28
Autor:
Catarina D Campbell, Kiana Mohajeri, Maika Malig, Fereydoun Hormozdiari, Benjamin Nelson, Gaixin Du, Kristen M Patterson, Celeste Eng, Dara G Torgerson, Donglei Hu, Catherine Herman, Jessica X Chong, Arthur Ko, Brian J O'Roak, Niklas Krumm, Laura Vives, Choli Lee, Lindsey A Roth, William Rodriguez-Cintron, Jose Rodriguez-Santana, Emerita Brigino-Buenaventura, Adam Davis, Kelley Meade, Michael A LeNoir, Shannon Thyne, Daniel J Jackson, James E Gern, Robert F Lemanske, Jay Shendure, Mark Abney, Esteban G Burchard, Carole Ober, Evan E Eichler
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104396 (2014)
Asthma is a complex genetic disease caused by a combination of genetic and environmental risk factors. We sought to test classes of genetic variants largely missed by genome-wide association studies (GWAS), including copy number variants (CNVs) and l
Externí odkaz:
https://doaj.org/article/98e7e72d10cd4b5ca2e3cbed7c9bd96a
Autor:
Susan M. Sunkin, Fabio Anaclerio, Claudia Rita Catacchio, Melanie Sorensen, Yafei Mao, Jason G. Underwood, AnneMarie E. Welch, John Huddleston, Weihong Jiang, Matthew E. Johnson, Katherine M. Munson, Maika Malig, Evan E. Eichler, PingHsun Hsieh, Ronald A. Conlon, Bruce T. Lamb, Max L. Dougherty, Santhosh Girirajan, Carl Baker, Arvis Sulovari, Stuart Cantsilieris, Mario Ventura
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-35 (2020)
Genome Biology
Genome Biology
Background The complex interspersed pattern of segmental duplications in humans is responsible for rearrangements associated with neurodevelopmental disease, including the emergence of novel genes important in human brain evolution. We investigate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b98b6b64acbc48f62875c6a901a3e6
https://doi.org/10.1186/s13059-020-02074-4
https://doi.org/10.1186/s13059-020-02074-4
Autor:
Maika Malig, Frédéric Chédin
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606797
Methods Mol Biol
Methods Mol Biol
R-loops are three-stranded structures that form during transcription when the nascent RNA hybridizes with the template DNA resulting in a DNA:RNA hybrid and a looped-out single-stranded DNA (ssDNA) strand. These structures are important for normal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0aadbea056c87f98420bac5653f6bf
https://doi.org/10.1007/978-1-0716-0680-3_15
https://doi.org/10.1007/978-1-0716-0680-3_15
Publikováno v:
J Mol Biol
Journal of molecular biology, vol 432, iss 7
Journal of molecular biology, vol 432, iss 7
R-loops are a prevalent class of non-B DNA structures that have been associated with both positive and negative cellular outcomes. DNA:RNA immunoprecipitation (DRIP) approaches based on the anti-DNA:RNA hybrid S9.6 antibody revealed that R-loops form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f92f8236af918b096e04e315f89dad0
https://pubmed.ncbi.nlm.nih.gov/32105733
https://pubmed.ncbi.nlm.nih.gov/32105733
R-loops are a prevalent class of non-B DNA structures that form during transcription upon reannealing of the nascent RNA to the template DNA strand. R-loops have been profiled using the S9.6 antibody to immunoprecipitate DNA:RNA hybrids. S9.6-based D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3352a210117596fe157c3dfb0e5b12
Autor:
Frédéric Chédin, Shaheen Sulthana, Robert Stolz, Maika Malig, Stella R. Hartono, Craig J. Benham
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 13
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Three-stranded R-loop structures form during transcription when the nascent RNA transcript rehybridizes to the template DNA strand. This creates an RNA:DNA hybrid and forces the nontemplate DNA strand into a single-stranded, looped-out s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85573e5cfad6ce4d573c07cc6464937
https://escholarship.org/uc/item/0vz4t8b4
https://escholarship.org/uc/item/0vz4t8b4
Autor:
Michael H. Duyzend, Iñigo Narvaiza, Giorgia Chiatante, Osnat Penn, John Huddleston, Francesca Camponeschi, Francesca Antonacci, Nicolette Janke, Kelsi Penewit, Joshua M. Akey, Giuliana Giannuzzi, Joshua G. Schraiber, W. Joyce Tang, Laura Denman, Peter H. Sudmant, Holly A.F. Stessman, Lana Harshman, Maria C. Marchetto, Evan E. Eichler, Xander Nuttle, Carl Baker, Mario Ventura, Lucia Banci, Chris T. Amemiya, Archana Raja, Alexandre Reymond, Maika Malig, Simone Ciofi-Baffoni, Fred H. Gage, Christopher Benner
Publikováno v:
Nature, vol 536, iss 7615
Nature
Nature, vol. 536, no. 7615, pp. 205-209
Peter Sudmant
Nature
Nature, vol. 536, no. 7615, pp. 205-209
Peter Sudmant
Genetic differences that specify unique aspects of human evolution have typically been identified by comparative analyses between the genomes of humans and closely related primates, including more recently the genomes of archaic hominins. Not all reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ea85b5b82a73d3282420dfdffcdc06
https://doi.org/10.1038/nature19075
https://doi.org/10.1038/nature19075