Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maika Dunst"'
Autor:
Daniel Spitzer, Tim Puetz, Moritz Armbrust, Maika Dunst, Jadranka Macas, Florian Croll, Karl-Heinz Plate, Yvonne Reiss, Stefan Liebner, Patrick N. Harter, Sylvaine Guérit, Kavi Devraj
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Ischemic stroke is a serious neurological disorder that is associated with dysregulation of the neurovascular unit (NVU) and impairment of the blood–brain barrier (BBB). Paradoxically, reperfusion therapies can aggravate NVU and BBB dysfun
Externí odkaz:
https://doaj.org/article/ce93e26c35be4d449ce4dd8574a39c2b
Autor:
Daniel Spitzer, Sylvaine Guérit, Tim Puetz, Maryam I. Khel, Moritz Armbrust, Maika Dunst, Jadranka Macas, Jenny Zinke, Gayatri Devraj, Xiaoxiong Jia, Florian Croll, Kathleen Sommer, Katharina Filipski, Thomas M. Freiman, Mario Looso, Stefan Günther, Mariangela Di Tacchio, Karl-Heinz Plate, Yvonne Reiss, Stefan Liebner, Patrick N. Harter, Kavi Devraj
Publikováno v:
Acta neuropathologica. 144(2)
Blood–brain barrier (BBB) dysfunction, characterized by degradation of BBB junctional proteins and increased permeability, is a crucial pathophysiological feature of acute ischemic stroke. Dysregulation of multiple neurovascular unit (NVU) cell typ
Autor:
Anne K. Braczynski, Werner Stenzel, Ulrich Drott, Cornelia Penski, Pia S. Zeiner, C. Preusse, Maika Dunst, Dominique-Suzanne Tews, Joachim Weis, Patrick N. Harter, Michel Mittelbronn
Publikováno v:
Neuromuscular Disorders. 26:283-291
Deposits of the terminal-membrane-attack-complex (MAC) C5b-9 on perfascicular endomysial capillaries are generally regarded as diagnostic hallmark of dermatomyositis (DM). Although the pathophysiology is not clear, C5b-9 deposits on capillaries seem
Autor:
Peter Baumgarten, Benjamin Goeppert, Anna-Eva Blank, Joachim P. Steinbach, Katharina Hoffmann, Lisa Mäder, Elke Hattingen, Michel Mittelbronn, Patrick N. Harter, Oliver Bähr, Volker Seifert, Pia S. Zeiner, Kea Franz, Karl H. Plate, Marcia Machein, Maika Dunst
Publikováno v:
Neuro-Oncology. 18:173-183
BACKGROUND A major hallmark of malignant progression in human astrocytomas is the formation of new blood vessels. Antiangiogenic therapy using the anti-vascular endothelial growth factor (VEGF)-antibody bevacizumab leads to increased progression-free
Autor:
Dominique S. Tews, Jens Schittenhelm, Karl H. Plate, Maika Dunst, Marco Skardelly, Lioba Imoehl, Volker Seifert, Peter Baumgarten, Christian Senft, Florian Gessler, Joachim P. Steinbach, Michel Mittelbronn, Patrick N. Harter, Marlies Wagner
Publikováno v:
Acta Neuropathologica. 132:479-481
Electronic supplementary material The online version of this article (doi: 10.1007/s00401-016-1598-1 ) contains supplementary material, which is available to authorized users.
Autor:
Patrick N. Harter, Volker Seifert, Joachim P. Steinbach, Johannes Rieger, Sebastian Eibach, Anne K. Braczynski, Elke Hattingen, Michel Mittelbronn, Oliver Bähr, Lutz Weise, Karl H. Plate, Maika Dunst
Publikováno v:
Stereotactic and Functional Neurosurgery. 92:129-139
Background: In nonresectable glioblastoma (GBM), stereotactic biopsies are performed to retrieve tissue for diagnostic purposes. The analysis of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation adds prognostic and predictive informa
Autor:
Lutz M, Weise, Patrick N, Harter, Sebastian, Eibach, Anne K, Braczynski, Maika, Dunst, Johannes, Rieger, Oliver, Bähr, Elke, Hattingen, Joachim P, Steinbach, Karl H, Plate, Volker, Seifert, Michel, Mittelbronn
Publikováno v:
Stereotactic and functional neurosurgery. 92(3)
In nonresectable glioblastoma (GBM), stereotactic biopsies are performed to retrieve tissue for diagnostic purposes. The analysis of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation adds prognostic and predictive information.The aim
Autor:
Seán M. Kilbride, Maika Dunst, Christian Senft, Markus Rehm, Brona M. Murphy, Jakob Weissenberger, Donat Kögel, Heinrich J. Huber, Jochen H. M. Prehn, Jasmin Schmid, Aine C. Murphy, B Weyhenmeyer, Volker Seifert, Michel Mittelbronn
Publikováno v:
Cell Death & Disease
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. GBM cells are highly resistant to apoptosis induced by antitumor drugs and radiotherapy resulting in cancer progression. We assessed whether a systems medicine approa