Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maik Obendorf"'
Autor:
Manman Guo, Cemsel Bafligil, Thomas Tapmeier, Carol Hubbard, Sanjiv Manek, Catherine Shang, Fernando O. Martinez, Nicole Schmidt, Maik Obendorf, Holger Hess-Stumpp, Thomas M. Zollner, Stephen Kennedy, Christian M. Becker, Krina T. Zondervan, Adam P. Cribbs, Udo Oppermann
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Endometriosis is a gynaecological condition characterised by immune cell infiltration and distinct inflammatory signatures found in the peritoneal cavity. In this study, we aim to characterise the immune microenvironment in sample
Externí odkaz:
https://doaj.org/article/15f988e46be6442287146db61267c609
Autor:
Stefanie Mesch, Christian M. Becker, Maik Obendorf, Jianghai Lin, Catherine Shang, Nilufer Rahmioglu, Muthuswamy Raveendran, Ronald A. Harris, Jeffrey Rogers, Oliver Fischer, Grant W. Montgomery, Graham Wells, Udo Oppermann, Heather A. Simmons, Bianca De Leo, Joseph W. Kemnitz, Nicholas G. Martin, Denise Brocklebank, Cemsel Bafligil, Thomas M. Zollner, Sanjiv Manek, Manman Guo, Krina T. Zondervan, Ernesto Lowy, Holger Hess-Stumpp, Jens Nagel, Fernando O. Martinez, Andrew P. Morris, Gerton Lunter, Susan A. Treloar, Alexis Laux-Biehlmann, Stephen Kennedy, Thomas T. Tapmeier, Jessica Malzahn
Publikováno v:
Science Translational Medicine. 13
Endometriosis is a common chronic inflammatory condition causing pelvic pain and infertility in women, with limited treatment options and 50% heritability. We leveraged genetic analyses in two species with spontaneous endometriosis, humans and the rh
Autor:
Christian M. Becker, Thomas T. Tapmeier, Manman Guo, Udo Oppermann, Sanjiv Manek, Maik Obendorf, Fernando O. Martinez, Catherine Shang, Holger Hess-Stumpp, Carol Hubbard, Stephen Kennedy, Krina T. Zondervan, Thomas M. Zollner, Nicole Schmidt, Adam P. Cribbs, Cemsel Bafligil
Publikováno v:
BMC Medicine
Guo, M, Bafligil, C, Tapmeier, T T, Hubbard, C, Manek, S, Shang, C, Martinez, F O, Schmidt, N, Obendorf, M, Hess-Stumpp, H, Zollner, T M, Kennedy, S, Becker, C M, Zondervan, K T, Cribbs, A P & Oppermann, U 2020, ' Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study ', BMC Medicine . https://doi.org/10.1186/s12916-019-1470-y
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Guo, M, Bafligil, C, Tapmeier, T T, Hubbard, C, Manek, S, Shang, C, Martinez, F O, Schmidt, N, Obendorf, M, Hess-Stumpp, H, Zollner, T M, Kennedy, S, Becker, C M, Zondervan, K T, Cribbs, A P & Oppermann, U 2020, ' Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study ', BMC Medicine . https://doi.org/10.1186/s12916-019-1470-y
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Background Endometriosis is a gynaecological condition characterised by immune cell infiltration and distinct inflammatory signatures found in the peritoneal cavity. In this study, we aim to characterise the immune microenvironment in samples isolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c2a1a4437ca3545df1ea3b161c681e
https://doi.org/10.1186/s12916-019-1470-y
https://doi.org/10.1186/s12916-019-1470-y
Autor:
Vladimir K. Patchev, Dorothee Girbig, Bernd-Wolfgang Igl, Maik Obendorf, Katja Prelle, Tanja Lehmann
Publikováno v:
Menopause. 19:909-915
Objective Estrogen supplementation is considered a reliable therapeutic approach to symptoms of vasomotor dysregulation (hot flashes) associated with the menopausal transition and sex hormone deprivation. Implication of changes in central neurotransm
Publikováno v:
Archives of Biochemistry and Biophysics. 460:56-66
Evidence is accumulating in support of the view that tissue-specific effects of steroid hormones depend on the recruitment of nuclear receptor comodulator proteins. The latter interact directly with the hormone receptors and modify their transcriptio
Autor:
Vladimir K. Patchev, Maik Obendorf
Publikováno v:
Current Drug Target -Inflammation & Allergy. 3:425-433
Differential sex-specific liability to inflammatory and autoimmune diseases, and changes in symptom severity in association with physiological fluctuations in gonadal secretions are indicative of significant contribution of sex hormones to the regula
Publikováno v:
Journal of Biological Chemistry. 275:6566-6572
The distinct protein and lipid constituents of the apical and basolateral membranes in polarized cells are sorted by specific signals. O-Glycosylation of a highly polarized intestinal brush-border protein sucrase isomaltase is implicated in its apica
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 107(1-2)
The basal transcriptional activity of nuclear receptors (NRs) is regulated by interactions with additional comodulator proteins (coactivator/corepressor). Here, we describe a new androgen receptor (AR)-associated coactivator, PRMT2, which belongs to
Autor:
Jens Dr. Schröder, Youri A. Mitev, Maik Obendorf, Konstanze Henning, Siegmund Wolf, Vladimir K. Patchev, Rene Meyer
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 104(3-5)
The androgen receptor (AR) is a ligand-dependent transcriptional regulator which belongs to the nuclear receptor superfamily. The basal transcriptional activity of the androgen receptor is regulated by interaction with coactivator or corepressor prot
Autor:
Ludger Ständker, Bernd Kübler, Thomas Braulke, Wolf-Georg Forssmann, Silke Mark, Maik Obendorf
Publikováno v:
Biochemical and biophysical research communications. 304(4)
Proteolysis of insulin-like growth factor binding proteins (IGFBPs), the major carrier of insulin-like growth factors (IGFs) in the circulation, is an essential mechanism to regulate the bioavailability and half-live of IGFs. Screening for peptides i