Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maik M. A. Worlitzer"'
Autor:
Alexis Vrachimis, Maik M. A. Worlitzer, Lydia Wachsmuth, Jens Christian Schwamborn, Andreas Faust, Inga B. Fricke, Thomas Viel, Franziska Melanie Collmann, Klaus P. Schäfers, Michael T. Kuhlmann, Sven Hermann, Andreas H. Jacobs, Frédéric Dollé, Cornelius Faber
Publikováno v:
The European journal of neuroscience. 43(10)
Parkinson's disease is a slowly progressing neurodegenerative disorder caused by loss of dopaminergic neurons in the substantia nigra (SN), leading to severe impairment in motor and non-motor functions. Endogenous subventricular zone (SVZ) neural ste
Publikováno v:
Neuroscience. 266
In the adult mammalian brain niches for neural stem cells are maintained, which enable a steady-state neurogenesis. This process is tightly regulated by multiple niche factors, including Notch and NF-κB signaling. The NF-κB-activating-protein (NKAP
Autor:
Lamia’a Bahnassawy, Jens Christian Schwamborn, Maik M. A. Worlitzer, Lars Lewejohann, Thomas Palm, Anna-Lena Hillje, Elisabeth Beckmann, Maria Angeliki S. Pavlou
Publikováno v:
Cell Death & Disease
In the adult mammalian brain, neural stem cells in the subventricular zone continuously generate new neurons for the olfactory bulb. Cell fate commitment in these adult neural stem cells is regulated by cell fate-determining proteins. Here, we show t
Publikováno v:
The European journal of neuroscience. 38(5)
Parkinson's disease is characterized by a selective loss of dopaminergic neurons in the substantia nigra (SN). However, whether regenerative endogenous neurogenesis is taking place in the mammalian SN of parkinsonian and non-parkinsonian brains remai
Autor:
Lamia A Bahnassawy, Sandra Stelzer, Eva C. Bunk, Kathrin Hemmer, Jens Christian Schwamborn, Kirite Rugani, Benjamin F. Brinkmann, Anna-Lena Schon, Maik M. A. Worlitzer, Klaus Ebnet, Thomas Palm, Inga Werthschulte
Publikováno v:
Stem cells and development. 21(5)
Junctional adhesion molecule-C (JAM-C) is an adhesive cell surface protein expressed in various cell types. JAM-C localizes to the apically localized tight junctions (TJs) between contacting endothelial and epithelial cells, where it contributes to c
Publikováno v:
Stem cells (Dayton, Ohio). 29(9)
Several studies over the last couple of years have delivered insights into the mechanisms that drive neuronal differentiation. However, the mechanisms that ensure the maintenance of stemness characteristics in neural stem cells over several rounds of