Residuale axilläre Metastasenlast nach neoadjuvanter Chemotherapie (NACT) bei Patientinnen mit Mammakarzinom im Frühstadium und a priori klinisch okkulten Lymphknotenmetastasen – eine transSENTINA-Analyse

Autor: Gisela Helms, Peter Schrenk, Annette Lebeau, Thorsten Kühn, Maja Krajewska, Tanja N. Fehm, A Stäbler, Sabine Schmatloch, Michael Untch, Hans-Christian Kolberg, Cornelia Kolberg-Liedtke, Barbara Fleige, Lukas Schwentner, Maik Hauschild, Sibylle Loibl, Ingo Bauerfeind

Publikováno v: Senologie - Zeitschrift für Mammadiagnostik und -therapie. 18:294-301

Zusammenfassung Hintergrund Der Zusammenhang zwischen pathologischer Komplettremission (pCR) der Brust und klinischen/pathologischen Parametern ist bei Brustkrebspatientinnen, die sich einer neoadjuvanten Chemotherapie (NACT) unterziehen, bekannt. No

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfcbfa8a91c5de08f76078a40dee2b2b
https://doi.org/10.1055/a-1578-9477

Abstract P3-13-06: Development and validation of a nomogram predicting pathological axillary status (ypN0 vs. ypN+) in a subgroup of patients converting from cN+ to ycN0 through neoadjuvant therapy (NAT) – A transSENTINA substudy

Autor: Cornelia Liedtke, Michael Untch, S. Loibl, G. von Minckwitz, Gisela Helms, Tanja Fehm, Ingo Bauerfeind, Annette Staebler, Sabine Schmatloch, P Schrenk, L Kerschke, Annette Lebeau, Barbara Fleige, Dennis Goerlich, H-C Kolberg, Maik Hauschild, Lukas Schwentner, T. Kuehn

Publikováno v: Cancer Research. 77:P3-13

Background: Particularly among patients converting from cN+ to ycN0 status through neoadjuvant therapy (NAT) the optimal method and extent of axillary staging is unclear. The aim of this analysis was to develop a nomogram predicting the probability o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08edeaf2b7d03273c9927f652ab34902
https://doi.org/10.1158/1538-7445.sabcs16-p3-13-06

Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study

Autor: Stefano Iacobelli, Malgorzata Foszczynska-Kloda, Soo-Chin Lee, Richard A. Michaelson, Juan Lacava, Raymond Smith, Vichien Srimuninnimit, Mauricio Kotliar, William Audeh, Damir Vrbanec, Young-Hyuck Im, Paola Edith Price, Maria Del Pilar, Barbara Bower, Tadeusz Pienkowski, Jedzada Maneecahvakajorn, Seppo Pyrhoenen, Alexander Marmé, Saverio Cinieri, Vladimir Semiglazov, Luciano Latini, Luis Miguel, Thitiya Sirisinha, Mario Matwiejuk, Jose Luiz Pedrini, John Allan Ellerton, Maik Hauschild, Xiaojia Wang, Christoph Maintz, Joohyuk Sohn, Estefania Monturus, Kenjiro Aogi, Eugeny Gotovkin, Ron Blachy, Douglas Otero Reye, Rita Blanchard, Bahriye Aktas, Adam Knott, Norberto Batista Lopez, L Roman, Reiki Nishimura, Piotr Tomczak, Duncan Wheatley, Emilio Alba Conejo, Yoshinori Itoh, Giraldo Kato, Petar Stefanovski, Rosa Jochim, Christoph Thomssen, Brigitte Van Eyll, Yutaka Tokuda, S O'Reilly, Paulette Blanchet, Ion Boiangiu, Nikola Vasev, Sherko Kümmel, Julie Taguchi, Do Youn Oh, David Miles, Jurandyr Andrade, Nora Giacomi, Volkmar Mueller, Eduardo Côrtes, Paula Klein, Eleonora Restuccia, Xuenong Ouyang, Leanne Budde, Andre Kallab, Elżbieta Starosławska, Takayuki Ueno, Taral Patel, Jun Horiguchi, Gilson Delgado, Sue Prill, Carol Peterson, Lourdes Calvo, Andreas Kirsch, Gustavo Ismael, Liwei Wang, Veena Charu, Dino Amadori, Pirkko Kellokumpu-Lehtinen, Brooke R. Daniel, Frank Senecal, Sanjay Yadav, Vera Gorbunova, Mikhail Kopp, Patrapim Sunpaweravong, Hiroji Iwata, Frank Priou, Kazuhiko Nakagami, Alejandra Perez, Michael R. Clemens, Marcus Schmidt, Denise A. Yardley, Birgitta Wesenberg, Priscilla Caguioa, Haruki Ogata, An Nguyen, Sung Bae Kim, Tsz-Kok Yau, Vladimir Merculov, Mikhail Lichinitser, Valorie Chan, Yoshiaki Rai, Neville Davidson, Walter E. Aulitzky, Gloria Martinez, Koji Takeda, Sherene Loi, Junichiro Watanabe, Louis Fehrenbacher, Gunta Purkalne, Shaker R. Dakhil, Claudia Schumacher, Rizvana Ahmad, Winnie Yeo, Christine Brezden-Masley, Alison Jones, Seock-Ah Im, Zetina Toache, Jeffrey Hargis, Celia Tosello, Tania Soria, Catia Angiolini, Maria De Fatima Gaui, Ravi Patel, Christopher Lobo, Andreas Schneeweiss, Priyanka Sharma, Cesar Estuardo, Randall Thomas, Adam Brufsky, Virote Sriuranpong, Zhenzhou Shen, Sandra Franco, Clive Mulatero, Wojciech Polkowski, Maria Alejandra Bartoli, Shigehira Saji, Patrick J. Flynn, Kimberly L. Blackwell, Gladys Rodriguez, Robert Robles, Timothy J. O'Rourke, Fabio Franke, Gabriel Tellez-Trevilla, Robert R. Carroll, Laura Biganzoli, Cheng Ying, Peter A. Kaufman, Mark Karwal, Mirta Varela, Darcy Spicer, Jonathan Polikoff, Roberto Hegg, Jungsil Ro, Pedro Sánchez-Rovira, Takahiro Nakayama, Edda Simoncini, María Bianconi, Liljana Kostovska-Maneva, Hugo Castro, Elza Grincuka, Jeff Neidhart, Anne Robinson, Nathan B. Green, Robert Hermann, Laura Assersohn, Teresa Gamucci, Dennis Tudtud, Nobuaki Sato, Antonio Gonzalez Martin, Victor Hugo Alencar, Jess Armor, Bruno Coudert, Nuria Ribelles, Eva Ciruelos, Daniel Cubero, Iveta Kudaba, Eduardo Cronemberger, Norikazu Masuda, Norio Kohno, Sergio J Azevedo, Vadim Shirinkin, Miguel Gil I Gil, Serafin Morales, Hirofumi Fujii, Chris Gallagher, Hernandez Monroy, Katsumasa Kuroi, Rodrigo Moura, Richy Agajanian, Zeljko Soldic, Jean-Marc Ferrero, Kenichi Inoue, Mark C. Benyunes, Davi Jendiroba, Filippo Montemurro, Masahiro Kashiwaba, Robert Quackenbush, Koichiro Tsugawa, Paulo M. Hoff, Eva-Maria Grischke, Susana De La Cruz, Vincent Hansen, Marianna Bitina, Carolyn B. Hendricks, Javier Cortes, Zee Wan Wong, Igor Kiselev, David Waterhouse, Javier Hornedo Muguiro, Mario Campone, Marianne Just, Emma Clark, Rodrigo Pereira, Sandra M Swain, Ruemu E. Birhiray, Helio Pinczowski, Wichit Arpornwirat

Publikováno v: The Lancet. Oncology. 21(4)

Summary Background CLEOPATRA was a phase 3 study comparing the efficacy and safety of pertuzumab, trastuzumab, and docetaxel with placebo, trastuzumab, and docetaxel in patients with HER2-positive metastatic breast cancer. In the primary analysis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e284b6f4b09c71b9922a7f657773bd0
https://pubmed.ncbi.nlm.nih.gov/32171427

Abstract OT-23-03: Pre- versus sub-pectoral implant-based breast reconstruction after skin-sparing mastectomy or nipple-sparing mastectomy (OPBC-02 PREPEC): A pragmatic, multicenter, randomized, superiority trial

Autor: Joerg Heil, Linda Nigard, Matthias Schwenkglenks, Zoltán Mátrai, Elisabeth A. Kappos, Colin Simonson, Subrina Farah, Frank Zimmermann, Rosine Mucklow, Mihai A. Constantinescu, Jian Farhadi, Daniel R. Zwahlen, Yves Harder, Vesna Bjelic-Radisic, Jana de Boniface, Judith E Lupatsch, Xiasong Chen, Yoon S. Chun, Roland Reitsamer, Dimitri Sarlos, Ilario Fulco, Giusi Moffa, Martin Haug, Thomas Holzbach, Mathias K. Fehr, Shelley Potter, Ralph Verstappen, Thomas Fischer, Christoph Tausch, Michael Knauer, Meredith M. Regan, Sherko Kümmel, Florian Fitzal, Maik Hauschild, Andrea L. Pusic, Amelia Chiorescu, Christian Kurzeder, Lars G. Hemkens, Karin Ribi, Alexandra Schulz, Heiner C. Bucher, Walter P. Weber

Publikováno v: Cancer Research. 81:OT-23

Background The emphasis on aesthetic outcomes and quality of life (QoL) has motivated surgeons to develop skin- and nipple-sparing mastectomy (SSM/NSM) for breast cancer (BC) treatment or prevention. Immediate breast reconstruction is based on implan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::856eaae25a8adf2e1fb1862e6aaa6225
https://doi.org/10.1158/1538-7445.sabcs20-ot-23-03

Association of clinical/pathological parameters with axillary involvement in early breast cancer in patients with limited sentinel node involvement after neoadjuvant chemotherapy (NACT)

Autor: Ingo Bauerfeind, Thorsten Kühn, Cornelia Liedtke, Lukas Schwentner, Gunter von Minckwitz, S Schmatloch, H-C Kolberg, Barbara Fleige, Gisela Helms, Maik Hauschild, Annette Lebeau, A Stäbler, S Loibl, P Schrenk, TN Fehm, M Untch

Publikováno v: Senologie - Zeitschrift für Mammadiagnostik und -therapie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6653f3ef775ae9f16536c8fbfe03271
https://doi.org/10.1055/s-0038-1651745