Influence of Biopsy Technique on Molecular Genetic Tumor Characterization in Non-Small Cell Lung Cancer—The Prospective, Randomized, Single-Blinded, Multicenter PROFILER Study Protocol

Autor: Maik Haentschel, Michael Boeckeler, Irina Bonzheim, Florian Schimmele, Werner Spengler, Franz Stanzel, Christoph Petermann, Kaid Darwiche, Lars Hagmeyer, Reinhard Buettner, Markus Tiemann, Hans-Ulrich Schildhaus, Rainer Muche, Hans Boesmueller, Felix Everinghoff, Robert Mueller, Bijoy Atique, Richard A. Lewis, Lars Zender, Falko Fend, Juergen Hetzel

Publikováno v: Diagnostics, Vol 10, Iss 7, p 459 (2020)

The detection of molecular alterations is crucial for the individualized treatment of advanced non-small cell lung cancer (NSCLC). Missing targetable alterations may have a major impact on patient’s progression free and overall survival. Although l

Externí odkaz: https://doaj.org/article/164524e895c94c218129cbf72bb795ed

A reply to 'A modern approach to Advanced Non-Small Cell Lung Cancer: Minimally-invasive procedures and in parallel multiple DNA/RNA high-throughput sequencing'

Autor: Juergen Hetzel, Hans Boesmueller, Ahmed Ehab, Robert Wagner, Maik Haentschel, Falko Fend, Marius Horger, Werner Spengler, Michael Boeckeler, Richard A. Lewis, Lothar Kanz, Irina Bonzheim, Volker Steger

Publikováno v: Lung cancer (Amsterdam, Netherlands). 146

We would like to thank G. Rossi et al. for their interest and taking the time to comment on our manuscript "Cryobiopsy increases the EGFR detection rate in non-small cell lung cancer”.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6d9243cc39b1db1a230f518750f3cf
https://pubmed.ncbi.nlm.nih.gov/32473823

A new functional method to choose the target lobe for lung volume reduction in emphysema – comparison with the conventional densitometric method

Autor: Richard A. Lewis, Ahmed Ehab, Robert Wagner, Dirk-Jan Slebos, Marius Horger, Juergen Hetzel, Christopher Kloth, Lutz Freitag, Michael Boeckeler, Maik Haentschel

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease
International Journal of Chronic Obstructive Pulmonary Disease, 12, 2621-2628. DOVE MEDICAL PRESS LTD

Juergen Hetzel,1 Michael Boeckeler,1 Marius Horger,2 Ahmed Ehab,1 Christopher Kloth,2 Robert Wagner,3 Lutz Freitag,4 Dirk-Jan Slebos,5 Richard Alexander Lewis,6 Maik Haentschel1 1Division of Haematology, Oncology, Rheumatology, Immunology and Pulmono

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9771233bba5b1ca1ea034f1fd4de86a3
https://doi.org/10.2147/copd.s139304

Transbronchial cryobiopsies for the diagnosis of diffuse parenchymal lung diseases: expert statement from the Cryobiopsy Working Group on safety and utility and a call for standardization of the procedure

Autor: Simon L.F. Walsh, Claudia Ravaglia, Martin Hetzel, Venerino Poletti, Jürgen Hetzel, Pallav L. Shah, Thomas V. Colby, Lonny Yarmus, Jouke T. Annema, Marco Chilosi, Ganesh Krishna, Lars Hagmeyer, Nicola Sverzellati, Oren Fruchter, Jay H. Ryu, Sara Tomassetti, Kaid Darwiche, Sara Piciucchi, Dominique Valeyre, Athol U. Wells, Fabien Maldonado, Alessandra Dubini, Stefano Gasparini, Alfonso Torrego, Alberto Cavazza, Maik Haentschel, Felix J.F. Herth, Dimitri Leduc, Ralf Eberhardt

Publikováno v: Respiration; international review of thoracic diseases, 95(3), 188-200. S. Karger AG
Hetzel, J, Maldonado, F, Ravaglia, C, Wells, A U, Colby, T V, Tomassetti, S, Ryu, J H, Fruchter, O, Piciucchi, S, Dubini, A, Cavazza, A, Chilosi, M, Sverzellati, N, Valeyre, D, Leduc, D, Walsh, S L F, Gasparini, S, Hetzel, M, Hagmeyer, L, Haentschel, M, Eberhardt, R, Darwiche, K, Yarmus, L B, Torrego, A, Krishna, G, Shah, P L, Annema, J T, Herth, F J F & Poletti, V 2018, ' Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases : Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure ', Respiration, vol. 95, no. 3, pp. 188-200 . https://doi.org/10.1159/000484055

Transbronchial cryobiopsies (TBCB) have recently been introduced as a promising and safer alternative to surgical lung biopsy in the diagnostic approach to diffuse parenchymal lung diseases (DPLD). Despite a substantial and expanding body of literatu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b77405f3cbf13e3f811c843430a004
http://hdl.handle.net/10044/1/58610

Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy

Autor: Marius Horger, Lothar Kanz, Susanne M Rittig, Steve Pascolo, Wolfram Brugger, Tobias A W Holderried, Arnulf Stenzl, O. Maksimovic, Ingmar Hoerr, Annkristin Heine, Katrin J Weimer, Peter Brossart, Martin Müller, Hans-Georg Rammensee, Maik Haentschel

Publikováno v: Oncoimmunology

Renal cell carcinoma (RCC) is an immunogenic tumor for which immunotherapeutic approaches could be associated with clinically relevant responses. It was recently shown, that induction of T-cell responses against multiple tumor-associated antigen (TAA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486394a58694614550dff736bcca7471
http://europepmc.org/articles/PMC4910748