Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Maik, Luu"'
Autor:
Felix F. Krause, Kira I. Mangold, Anna-Lena Ruppert, Hanna Leister, Anne Hellhund-Zingel, Aleksandra Lopez Krol, Jelena Pesek, Bernhard Watzer, Sarah Winterberg, Hartmann Raifer, Kai Binder, Ralf Kinscherf, Alesia Walker, Wolfgang A. Nockher, R. Verena Taudte, Wilhelm Bertrams, Bernd Schmeck, Anja A. Kühl, Britta Siegmund, Rossana Romero, Maik Luu, Stephan Göttig, Isabelle Bekeredjian-Ding, Ulrich Steinhoff, Burkhard Schütz, Alexander Visekruna
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut microbiota-derived metabolites play a pivotal role in the maintenance of intestinal immune homeostasis. Here, we demonstrate that the human commensal Clostridium sporogenes possesses a specific metabolic fingerprint, consisting predominantly of t
Externí odkaz:
https://doaj.org/article/97ed57a0291145d689511c9029b8a47d
Autor:
Benno Lickefett, Lulu Chu, Valentin Ortiz-Maldonado, Linda Warmuth, Pere Barba, Matteo Doglio, David Henderson, Michael Hudecek, Andreas Kremer, Janet Markman, Magdalena Nauerth, Helene Negre, Carmen Sanges, Philipp B. Staber, Rebecca Tanzi, Julio Delgado, Dirk H. Busch, Jürgen Kuball, Maik Luu, Ulrich Jäger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Lymphodepletion (LD) or conditioning is an essential step in the application of currently used autologous and allogeneic chimeric antigen receptor T-cell (CAR-T) therapies as it maximizes engraftment, efficacy and long-term survival of CAR-T. Its mai
Externí odkaz:
https://doaj.org/article/867d97eccd50488c8737f46f9637a5f0
Autor:
Delphine Ammar, Inga Schapitz, Maik Luu, Michael Hudecek, Miriam Meyer, Timmothy Taps, Bernd Schröder, Zoltán Ivics, Carmen Sanges, Paul Franz, Ulrike Koehl, Helene Negre, Inez Johanna, Jacquelyn Awigena-Cook
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
To accelerate the development of Advanced Therapy Medicinal Products (ATMPs) for patients suffering from life-threatening cancer with limited therapeutic options, regulatory approaches need to be constantly reviewed, evaluated and adjusted, as necess
Externí odkaz:
https://doaj.org/article/5d384e6985d7461ba55323e181207b7d
Autor:
Sarah Staudt, Kai Ziegler-Martin, Alexander Visekruna, John Slingerland, Roni Shouval, Michael Hudecek, Marcel van den Brink, Maik Luu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The opportunities genetic engineering has created in the field of adoptive cellular therapy for cancer are accelerating the development of novel treatment strategies using chimeric antigen receptor (CAR) and T cell receptor (TCR) T cells. The great s
Externí odkaz:
https://doaj.org/article/c3512a04084f460ca535deb941c644e6
Autor:
Rossana Romero, Agnieszka Zarzycka, Mathieu Preussner, Florence Fischer, Torsten Hain, Jan-Paul Herrmann, Katrin Roth, Corinna U. Keber, Kushal Suryamohan, Hartmann Raifer, Maik Luu, Hanna Leister, Wilhelm Bertrams, Matthias Klein, Hosam Shams-Eldin, Ralf Jacob, Hans-Joachim Mollenkopf, Krishnaraj Rajalingam, Alexander Visekruna, Ulrich Steinhoff
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Background The intestinal microbiota fundamentally guides the development of a normal intestinal physiology, the education, and functioning of the mucosal immune system. The Citrobacter rodentium-carrier model in germ-free (GF) mice is suita
Externí odkaz:
https://doaj.org/article/b18804c7712b4fa8ab10a7d7819edd52
Autor:
Maik Luu, Zeno Riester, Adrian Baldrich, Nicole Reichardt, Samantha Yuille, Alessandro Busetti, Matthias Klein, Anne Wempe, Hanna Leister, Hartmann Raifer, Felix Picard, Khalid Muhammad, Kim Ohl, Rossana Romero, Florence Fischer, Christian A. Bauer, Magdalena Huber, Thomas M. Gress, Matthias Lauth, Sophia Danhof, Tobias Bopp, Thomas Nerreter, Imke E. Mulder, Ulrich Steinhoff, Michael Hudecek, Alexander Visekruna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The activity of immune cells can be regulated by the microbiome. Here, the authors show that the fatty acids pentanoate and butyrate—normally released by the microbiome—increase the anti-tumour activity of cytotoxic T lymphocytes and chimeric ant
Externí odkaz:
https://doaj.org/article/b049d4b46e18405fa995dd666bce268c
Autor:
Maik Luu, Alexander Visekruna
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/a7a9fb4c13b24e6f8150e1bf1e306854
Autor:
Alexander Visekruna, Maik Luu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
During the past decade, researchers have investigated the role of microbiota in health and disease. Recent findings support the hypothesis that commensal bacteria and in particular microbiota-derived metabolites have an impact on development of infla
Externí odkaz:
https://doaj.org/article/416c396fae294dca8c6afeeb632f5bc3
Autor:
Maik Luu, Sabine Pautz, Vanessa Kohl, Rajeev Singh, Rossana Romero, Sébastien Lucas, Jörg Hofmann, Hartmann Raifer, Niyati Vachharajani, Lucia Campos Carrascosa, Boris Lamp, Andrea Nist, Thorsten Stiewe, Yoav Shaul, Till Adhikary, Mario M. Zaiss, Matthias Lauth, Ulrich Steinhoff, Alexander Visekruna
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Short-chain fatty acids (SCFAs) have immunomodulatory effects, but the underlying mechanisms are still unclear. Here the authors show that a SCFA, pentanoate, suppresses autoimmune inflammation in mouse models of colitis and multiple sclerosis via ep
Externí odkaz:
https://doaj.org/article/d856e522710041fdbeadd9b5689c49a8
Autor:
Florence Fischer, Rossana Romero, Anne Hellhund, Uwe Linne, Wilhelm Bertrams, Olaf Pinkenburg, Hosam Shams Eldin, Kai Binder, Ralf Jacob, Alesia Walker, Bärbel Stecher, Marijana Basic, Maik Luu, Rouzbeh Mahdavi, Anna Heintz-Buschart, Alexander Visekruna, Ulrich Steinhoff
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Although it is generally accepted that dietary fiber is health promoting, the underlying immunological and molecular mechanisms are not well defined, especially with respect to cellulose, the most ubiquitous dietary fiber. Here, the impact of dietary
Externí odkaz:
https://doaj.org/article/66994b12046c4d7c80be7dcfafb70858