Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maik, Engeholm"'
Publikováno v:
Nature Structural and Molecular Biology
Throughout the genome, nucleosomes often form regular arrays that differ in nucleosome repeat length (NRL), occupancy of linker histone H1 and transcriptional activity. Here, we report cryo-EM structures of human H1-containing tetranucleosome arrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2c8d343732f28b582434f70fd6b7a5
https://doi.org/10.1038/s41594-022-00768-w
https://doi.org/10.1038/s41594-022-00768-w
Autor:
Julia Bender, Maik Engeholm, Marion S Ederer, Johannes Breu, Thor C Møller, Stylianos Michalakis, Tamas Rasko, Erich E Wanker, Martin Biel, Karen L Martinez, Wolfgang Wurst, Jan M Deussing
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136768 (2015)
The corticotropin-releasing hormone receptor type 1 (CRHR1) plays an important role in orchestrating neuroendocrine, behavioral, and autonomic responses to stress. To identify molecules capable of directly modulating CRHR1 signaling, we performed a y
Externí odkaz:
https://doaj.org/article/9d49b92304a34288ad9452b996ef64a7
Publikováno v:
Nature structural & molecular biology
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology
Efficient transcription of RNA polymerase II (Pol II) through nucleosomes requires the help of various factors. Here we show biochemically that Pol II transcription through a nucleosome is facilitated by the chromatin remodeler Chd1 and the histone c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79117d869f2eb890c746a7d5838d27a
https://doi.org/10.1101/2020.11.30.403857
https://doi.org/10.1101/2020.11.30.403857
Autor:
Nikolaus, Rieber, Roel P, Gazendam, Alexandra F, Freeman, Amy P, Hsu, Amanda L, Collar, Janyce A, Sugui, Rebecca A, Drummond, Chokechai, Rongkavilit, Kevin, Hoffman, Carolyn, Henderson, Lily, Clark, Markus, Mezger, Muthulekha, Swamydas, Maik, Engeholm, Rebecca, Schüle, Bettina, Neumayer, Frank, Ebel, Constantinos M, Mikelis, Stefania, Pittaluga, Vinod K, Prasad, Anurag, Singh, Joshua D, Milner, Kelli W, Williams, Jean K, Lim, Kyung J, Kwon-Chung, Steven M, Holland, Dominik, Hartl, Taco W, Kuijpers, Michail S, Lionakis
Publikováno v:
JCI insight. 1(17)
Invasive pulmonary aspergillosis is a life-threatening mycosis that only affects patients with immunosuppression, chemotherapy-induced neutropenia, transplantation, or congenital immunodeficiency. We studied the clinical, genetic, histological, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efec515b850d586b1f3164e1ab66f10a
https://pubmed.ncbi.nlm.nih.gov/27777981
https://pubmed.ncbi.nlm.nih.gov/27777981
Autor:
Bettina Neumayer, Michail S. Lionakis, Amy P. Hsu, Rebecca A. Drummond, Anurag Singh, Amanda L. Collar, Vinod K. Prasad, Jean K. Lim, Rebecca Schüle, Roel P. Gazendam, Alexandra F. Freeman, Maik Engeholm, Nikolaus Rieber, Frank Ebel, Dominik Hartl, Chokechai Rongkavilit, Stefania Pittaluga, Janyce A. Sugui, Constantinos M. Mikelis, Carolyn Henderson, Kelli W. Williams, Joshua D. Milner, Lily P. Clark, Taco W. Kuijpers, Kevin W. Hoffman, Muthulekha Swamydas, Kyung J. Kwon-Chung, Steven M. Holland, Markus Mezger
Publikováno v:
JCI insight, 1(17). The American Society for Clinical Investigation
Invasive pulmonary aspergillosis is a life-threatening mycosis that only affects patients with immunosuppression, chemotherapy-induced neutropenia, transplantation, or congenital immunodeficiency. We studied the clinical, genetic, histological, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670fc5f75a795acc3d6f44f8416e2e6e
https://pure.amc.nl/en/publications/extrapulmonary-aspergillus-infection-in-patients-with-card9-deficiency(ccf424c8-5232-4d8b-abb2-c4c2e6ef90be).html
https://pure.amc.nl/en/publications/extrapulmonary-aspergillus-infection-in-patients-with-card9-deficiency(ccf424c8-5232-4d8b-abb2-c4c2e6ef90be).html
Autor:
Thomas Gasser, Maik Engeholm
Publikováno v:
Movement Disorders. 28:1027-1029
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a7ba55ae496add83a0d5bd85f78e7d
https://doi.org/10.1002/mds.25611
https://doi.org/10.1002/mds.25611
Autor:
Maik, Engeholm, Julia, Sekler, David C, Schöndorf, Vineet, Arora, Jens, Schittenhelm, Saskia, Biskup, Caroline, Schell, Thomas, Gasser
Publikováno v:
BMC neurology 14(1), 118 (2014). doi:10.1186/1471-2377-14-118
BMC Neurology
BMC Neurology
Background Charcot-Marie-Tooth disease (CMT) refers to a heterogeneous group of genetic motor and sensory neuropathies. According to the primary site of damage, a distinction is made between demyelinating and axonal forms (CMT1 and 2, respectively, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a059c6b40c1a9dfdd755cd3b7c264590
Publikováno v:
Nature structural & molecular biology
Nucleosomes are the fundamental subunits of eukaryotic chromatin. They are not static entities, but can undergo a number of dynamic transitions, including spontaneous repositioning along DNA. As nucleosomes are spaced close together within genomes, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce2ca6cfae906dfb274d9331066ab49
https://pubmed.ncbi.nlm.nih.gov/19182801
https://pubmed.ncbi.nlm.nih.gov/19182801
Autor:
Tom Owen-Hughes, Maik Engeholm
Publikováno v:
Genome Biology
Massively parallel pyrosequencing used to map nucleosome positions genome-wide.
New parallel-sequencing technology has recently been used to map with unprecedented accuracy the positions of nucleosomes enriched for the histone variant H2A.Z thro
New parallel-sequencing technology has recently been used to map with unprecedented accuracy the positions of nucleosomes enriched for the histone variant H2A.Z thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da02f6e282faf3e7c714268e85956c6
https://doi.org/10.1186/gb-2007-8-6-217
https://doi.org/10.1186/gb-2007-8-6-217