Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maija Sarviharju"'
Autor:
Maija Sarviharju, Kalervo Kiianmaa, Antti Hervonen, C. J. Peter Eriksson, Noora Raivio, Pia Jaatinen
Publikováno v:
Brain Sciences, Vol 3, Iss 2, Pp 790-799 (2013)
The purpose of the present study was to examine the combined effects of aging and lifelong ethanol exposure on the levels of monoamine neurotransmitters in different regions of the brain. This work is part of a project addressing interactions of agin
Externí odkaz:
https://doaj.org/article/a7b39a9199ad43df93712fe90684a9d0
Autor:
Pia Jaatinen, Maija Sarviharju, Antti Hervonen, David A. Sinclair, Kalervo Kiianmaa, Jarno Riikonen
Publikováno v:
Alcoholism: Clinical and Experimental Research. 28:93-97
Background: Study of the long-term effects of chronic alcohol consumption in human populations is confounded by genetic and environmental factors. Methods: The study was intended to investigate the effects on morbidity and survival of lifetime forced
Publikováno v:
Alcoholism: Clinical & Experimental Research. 26:1344-1349
Background A rat line developed by selective breeding for high alcohol sensitivity has blunted corticosterone responses to alcohol and stress. In the present study, we determined possible differences in adrenal activation after alcohol and motor perf
Autor:
Mei Xu, Maija Sarviharju, Esa R. Korpi, Alessandro Guidotti, Mikko Uusi-Oukari, Riikka Mäkelä, Flavia di Michele, Per H. Rosenberg, Carmelo Furnari, Elena Romeo
Publikováno v:
European Journal of Pharmacology. 421:31-38
Acute administration of a neurosteroid 5beta-pregnan-3alpha-ol-20-one induced a greater impairment in motor performance of the selectively bred alcohol-sensitive (ANT) than alcohol-insensitive (AT) rats. This difference was not associated with the se
Autor:
Maija Sarviharju, Jyrki Rintala, Pia Jaatinen, Jarno Riikonen, Kalervo Kiianmaa, Oili Kemppainen, Antti Hervonen
Publikováno v:
Alcohol. 23:1-8
The effects of aging and lifelong ethanol consumption on astrocytic morphology and glial fibrillary acidic protein-immunoreactivity (GFAP-IR) in the cerebellar vermis obtained from ethanol-preferring Alko, Alcohol (AA) rats were analyzed by using com
Autor:
Jari Heikkilä, Aapo Honkanen, Olga Y. Vekovischeva, Riitta Näkki, Maija Sarviharju, Antti Haapalinna, Esa R. Korpi
Publikováno v:
Pharmacology Biochemistry and Behavior. 67:793-799
The ability of the antagonists for the N-methyl-D-aspartate (NMDA) type of glutamate receptor to modulate locomotor activity were compared in alcohol-sensitive (or alcohol-nontolerant, ANT) and alcohol-insensitive (or alcohol-tolerant, AT) rat lines.
Publikováno v:
Brain Research. 837:184-187
Alcohol-sensitive ANT rats have a point mutation in the cerebellum-enriched GABA(A) receptor alpha6 subunit, which makes this subunit and the ANT rats in vivo highly sensitive to benzodiazepine agonists. In the elevated plus maze test of anxiety, dia
Publikováno v:
European Journal of Pharmacology. 304:7-13
To assess the roles of opioid receptor subtypes in voluntary alcohol drinking, alcohol-preferring AA (Alko, Alcohol) rats, non-deprived of food or water, were used in a paradigm where access to 10% alcohol solution was limited to 1-4-h sessions on ev
Publikováno v:
Pharmacology Biochemistry and Behavior. 53:723-730
Alcohol-nontolerant (ANT) rats, produced by selective breeding for high sensitivity to motor-impairing effects of ethanol, have a point mutation in the cerebellar gamma-aminobutyric acid type A (GABAA) receptor alpha 6 subunit, which has been propose
Publikováno v:
Experimental Gerontology. 27:335-345
The interactions of aging and long-term voluntary ethanol consumption were studied in the alcohol-preferring AA (Alko Alcohol) rats. The mean daily ethanol intake was 6.45 ± 0.31 g/kg/dy (mean ± SE at the beginning of the exposure at 3 months of ag