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pro vyhledávání: '"Maija Sanna"'
Autor:
Kristin V. Tarbell, Tibor Warganich, Seon-Kyeong Kim, Maija Sanna, Mark Lee, Mary Vadeboncoeur, Mark M. Davis, Hugh O. McDevitt
Publikováno v:
Proceedings of the National Academy of Sciences. 101:14204-14209
Glutamic acid decarboxylase (GAD) 65 is one of the major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus. T cells specific for GAD65 are among the first to enter inflamed islets and may be important for the initiatio
Autor:
Peter Dickie, Erik A. Ranheim, Kristin V. Tarbell, Mark M. Davis, Hugh O. McDevitt, Luc Teyton, Cheng Chi Chao, Mark Lee, Maija Sanna, Seon-Kyeong Kim
Publikováno v:
The Journal of Experimental Medicine
Glutamic acid decarboxylase (GAD)65 is an early and important antigen in both human diabetes mellitus and the nonobese diabetic (NOD) mouse. However, the exact role of GAD65-specific T cells in diabetes pathogenesis is unclear. T cell responses to GA
Autor:
Mindy Tsai, Hugh O. McDevitt, Lawrence Steinman, Stephen J. Galli, Rosetta Pedotti, Maija Sanna, Jason J. DeVoss
Publikováno v:
BMC Immunology. 4:2
Insulin dependent (i.e., "type 1") diabetes mellitus (T1DM) is considered to be a T cell mediated disease in which TH1 and Tc autoreactive cells attack the pancreatic islets. Among the beta-cell antigens implicated in T1DM, glutamic acid decarboxylas