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pro vyhledávání: '"Maija H. Zile"'
Autor:
Maija H. Zile
Publikováno v:
Nutrients, Vol 2, Iss 5, Pp 532-550 (2010)
Vitamin A insufficiency has profound adverse effects on embryonic development. Major advances in understanding the role of vitamin A in vertebrate heart formation have been made since the discovery that the vitamin A active form, all-trans-retinoic a
Externí odkaz:
https://doaj.org/article/3a8881bbd26d4ea6be40f722a4b8eb9c
Publikováno v:
Development, Growth & Differentiation. 51:753-767
The vitamin A-deficient (VAD) early avian embryo has a grossly abnormal cardiovascular system that is rescued by treating the embryo with the vitamin A-active form, retinoic acid (RA). Here we examine the role of N-cadherin (N-cad) in RA-regulated ea
Publikováno v:
Biopolymers and Cell. 21:250-257
Publikováno v:
Developmental Dynamics. 228:697-708
Avian embryogenesis requires retinoid receptor activation by the vitamin A active form, retinoic acid (RA), during neurulation. We conducted loss-of-function analysis in quail embryos by nutritional deprivation of RA and by blocking generation of ret
Publikováno v:
Developmental Biology. 260(2):496-511
The functional links of specific retinoid receptors to early developmental events in the avian embryo are not known. Before such studies are undertaken, knowledge is required of the spatiotemporal expression patterns of the receptor genes and their r
Autor:
Andreas D. Ebert, Birgit Andrée, Hans-Henning Arnold, Ingo Schnipkoweit, Maija H. Zile, Thomas Brand, Thomas Schlange
Publikováno v:
Developmental Biology. 234:376-389
Members of the EGF-CFC family of proteins have recently been implicated as essential cofactors for Nodal signaling. Here we report the isolation of chick CFC and describe its expression pattern, which appears to be similar to Cfc1 in mouse. During ea
Autor:
Maija H. Zile
Publikováno v:
The Journal of Nutrition. 131:705-708
Advances in molecular biology and retinoic acid receptor research have significantly contributed to the understanding of the role of vitamin A during vertebrate development. Examination of the function of this vitamin during very early developmental
Autor:
YiPing Chen, Weihong Jiang, Tara R. St. Amand, Igor Kostetskii, Maija H. Zile, Saying Yuan, Ekaterina Kostetskaia
Publikováno v:
Developmental Biology. 223(2):323-338
Vitamin A-deficient (VAD) quail embryos have severe abnormalities, including a high incidence of reversed cardiac situs. Using this model we examined in vivo the physiological function of vitamin A in the left/right (L/R) cardiac asymmetry pathway. M
Publikováno v:
Developmental Biology. 219(1):59-70
The vitamin A deficient (VAD) quail embryo lacks active retinoids, fails to express normally GATA-4, and develops a nonlooping heart tube morphogenetic defect that is a model for congenital cardiomyopathy. VAD quail embryos, or chick embryos depleted
Autor:
Maija H. Zile, May Griffith
Publikováno v:
Teratology. 62:123-133
Background Retinoic acid (RA) is necessary for normal differentiation of the tail bud into the secondary neural tube. Excess RA, however, is teratogenic and causes neural tube defects (NTDs). The way in which RA modulates secondary neurulation is unc