Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Maider Zabala"'
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-8 (2018)
Abstract Background Recent studies in murine mammary tissue have identified functionally distinct cell populations that may be isolated by surface phenotype or lineage tracing. Previous groups have shown that CD24medCD49fhigh cells enriched for long-
Externí odkaz:
https://doaj.org/article/72dd897acabf4d08bc28d6807e5592bd
Autor:
Shaheen S. Sikandar, Angera H. Kuo, Tomer Kalisky, Shang Cai, Maider Zabala, Robert W. Hsieh, Neethan A. Lobo, Ferenc A. Scheeren, Sopheak Sim, Dalong Qian, Frederick M. Dirbas, George Somlo, Stephen R. Quake, Michael F. Clarke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The contribution of EMT in mammary gland homeostasis and human breast cancer is still unclear. Here, using in vivo lineage tracing and breast cancer PDXs the authors demonstrate that the repopulating capacity in normal mammary epithelial cells and tu
Externí odkaz:
https://doaj.org/article/f0f50f3b3e2d42029e585ebb81c7168c
Autor:
Taichi Isobe, Shigeo Hisamori, Daniel J Hogan, Maider Zabala, David G Hendrickson, Piero Dalerba, Shang Cai, Ferenc Scheeren, Angera H Kuo, Shaheen S Sikandar, Jessica S Lam, Dalong Qian, Frederick M Dirbas, George Somlo, Kaiqin Lao, Patrick O Brown, Michael F Clarke, Yohei Shimono
Publikováno v:
eLife, Vol 3 (2014)
MicroRNAs (miRNAs) are important regulators of stem and progenitor cell functions. We previously reported that miR-142 and miR-150 are upregulated in human breast cancer stem cells (BCSCs) as compared to the non-tumorigenic breast cancer cells. In th
Externí odkaz:
https://doaj.org/article/12df545b9b7f407281bc82e145ae3c9e
Autor:
Anjan Bharadwaj, Feiqiao Brian Yu, Robert W. Hsieh, Gunsagar S. Gulati, Aaron M. Newman, Dalong Qian, Ferenc A. Scheeren, Shang Cai, Frederick M. Dirbas, Daniel J. Wesche, Mark J. Berger, Francisco Ilagan, Michael F. Clarke, Angera H. Kuo, Maider Zabala, Neethan A. Lobo, Shaheen S. Sikandar, Anoop Manjunath
Publikováno v:
Science
Science, 367(6476), 405-+. AMER ASSOC ADVANCEMENT SCIENCE
Science, 367(6476), 405-+. AMER ASSOC ADVANCEMENT SCIENCE
Single-cell RNA-sequencing (scRNA-seq) is a powerful approach for reconstructing cellular differentiation trajectories. However, inferring both the state and direction of differentiation without prior knowledge has remained challenging. Here we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec50de330c26eb0f3f81a6f23c728afe
https://europepmc.org/articles/PMC7694873/
https://europepmc.org/articles/PMC7694873/
Autor:
Maider Zabala, Linus Li, Angera H. Kuo, Sopheak Sim, Luuk S. Heitink, Jane Antony, Michael F. Clarke, Gunsagar S. Gulati, Kassandra Sanchez, Dalong Qian, Aaron M. Newman, Maddalena Adorno, Natesh Parashurama, Jessica Lam, George Somlo, Tomer Kalisky, Neethan A. Lobo, Shaheen S. Sikandar, Stephen R. Quake, Frederick M. Dirbas
Publikováno v:
Cell Stem Cell. 27:284-299.e8
SMAD pathways govern epithelial proliferation, and transforming growth factor β (TGF-β and BMP signaling through SMAD members has distinct effects on mammary development and homeostasis. Here, we show that LEFTY1, a secreted inhibitor of NODAL/SMAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2860f7ab2f228299807d26a43ecc3c8
https://doi.org/10.1016/j.stem.2020.06.017
https://doi.org/10.1016/j.stem.2020.06.017
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-8 (2018)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background Recent studies in murine mammary tissue have identified functionally distinct cell populations that may be isolated by surface phenotype or lineage tracing. Previous groups have shown that CD24medCD49fhigh cells enriched for long-lived mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fb00d8ba4a2226aea19c6420c2fdb2
https://doi.org/10.1186/s13058-018-1006-y
https://doi.org/10.1186/s13058-018-1006-y
Autor:
Neethan A. Lobo, Sopheak Sim, Tomer Kalisky, Shang Cai, George Somlo, Dalong Qian, Angera H. Kuo, Shaheen S. Sikandar, Michael F. Clarke, Stephen R. Quake, Ferenc A. Scheeren, Frederick M. Dirbas, Maider Zabala, Robert W. Hsieh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications, 8
Nature Communications
Nature Communications, 8
Nature Communications
Previous studies have proposed that epithelial to mesenchymal transition (EMT) in breast cancer cells regulates metastasis, stem cell properties and chemo-resistance; most studies were based on in vitro culture of cell lines and mouse transgenic canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbb5f5f9e413746df11c19c8a5a0b72
https://hdl.handle.net/1887/95636
https://hdl.handle.net/1887/95636
Autor:
Michael E. Rothenberg, Iris E. Glykofridis, Tomer Kalisky, Debashis Sahoo, Michael F. Clarke, Maider Zabala, Matt van de Rijn, Linda J. van Weele, Shaheen S. Sikandar, Darius M. Johnston, Shang Cai, Stephen R. Quake, Angera H. Kuo, G. Somlo, Jens Peter Volkmer, Jessica Lam, Ferenc A. Scheeren, Frederick M. Dirbas, Dalong Qian
Publikováno v:
Nature Cell Biology. 16:1238-1248
It has been postulated that there is a link between inflammation and cancer. Here we describe a role for cell-intrinsic toll-like receptor-2 (TLR2; which is involved in inflammatory response) signalling in normal intestinal and mammary epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaed581deefa5eda3e204fe7c6527b0
https://doi.org/10.1038/ncb3058
https://doi.org/10.1038/ncb3058
Cancer cells within tumors differ in phenotype, genetic and epigenetic modifications and functions. In an increasing number of tumors, a proliferative hierarchy has been defined where a subpopulation of cells possesses self-renewal potential, similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c556046fdf7da8f621497e3df0b31b1
https://doi.org/10.1016/b978-0-12-803892-5.00002-4
https://doi.org/10.1016/b978-0-12-803892-5.00002-4
Autor:
Lauren Agro, Shideng Bao, Chi-Hsuan Chang, Keith Syson Chan, Samuel H. Cheshier, Avijeet S. Chopra, Anastasia Chumakova, Michael F. Clarke, Salvatore Condello, Leanne R. Donahue, Rogelio Esparza, Fang Fang, Christine Fillmore Brainson, Austin Gurney, Andrew Haller, Jennifer Haynes, Diane Heiser, Joy Q. He, Masahiro Hitomi, Timothy Hoey, Jason K. Hseih, Gregor Hutter, Awad Jarrar, Carla F. Kim, Molly Kozminsky, Antonina V. Kurtova, Justin D. Lathia, Cherry Leung, Evelyne Lima-Fernandes, Huiping Liu, Xia Liu, Neethan A. Lobo, Daniela Matei, Siddhartha S. Mitra, Hyeongsun Moon, Sunitha Nagrath, Kenneth P. Nephew, Catherine A. O’Brien, Claudia Petritsch, Akshita Puri, Dalong Qian, Sumaiyah Rehman, Ofer Reizes, Jeffrey M. Rosen, Kiera Rycaj, Yogen Saunthararajah, Xiling Shen, Andrew E. Sloan, Benjamin T. Spike, Swetha J. Sundar, Dean G. Tang, Praveena S. Thiagarajan, Linda J. van Weele, Yadong Wang, Yinu Wang, Irving Weissman, Andrew C. White, James Wright, Maider Zabala, Wenchao Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2223cb4e4a70949237b56af2419b44c6
https://doi.org/10.1016/b978-0-12-803892-5.01002-0
https://doi.org/10.1016/b978-0-12-803892-5.01002-0