Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maider Varela-Guruceaga"'
Autor:
Naiara Martínez-Vélez, Marc Garcia-Moure, Miguel Marigil, Marisol González-Huarriz, Montse Puigdelloses, Jaime Gallego Pérez-Larraya, Marta Zalacaín, Lucía Marrodán, Maider Varela-Guruceaga, Virginia Laspidea, Jose Javier Aristu, Luis Isaac Ramos, Sonia Tejada-Solís, Ricardo Díez-Valle, Chris Jones, Alan Mackay, Jose A. Martínez-Climent, Maria Jose García-Barchino, Eric Raabe, Michelle Monje, Oren J. Becher, Marie Pierre Junier, Elias A. El-Habr, Herve Chneiweiss, Guillermo Aldave, Hong Jiang, Juan Fueyo, Ana Patiño-García, Candelaria Gomez-Manzano, Marta M. Alonso
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The oncolytic virus Delta-24-RGD is in clinical trial for adult glioma. Here, the authors show that this virus elicits an immune response in mouse models of pediatric high-grade glioma and diffuse pontine intrinsic glioma, resulting in improved survi
Externí odkaz:
https://doaj.org/article/e70b68b3d2c14bafb5f5185c1fba26c6
Autor:
Maider Varela-Guruceaga, Elise Belaidi, Lucie Lebeau, Ella Aka, Ramaroson Andriantsitohaina, Sophie Giorgetti-Peraldi, Claire Arnaud, Soazig Le Lay
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders. In humans, an association between OSA and
Externí odkaz:
https://doaj.org/article/da02a888ba3340869a72b8842ef792b9
Autor:
Sara Palacios-Ortega, Maider Varela-Guruceaga, Miriam Algarabel, Fermín Ignacio Milagro, J. Alfredo Martínez, Carlos de Miguel
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 4, Pp 1499-1516 (2015)
Background/Aims: Tumor necrosis factor-α (TNF-α)-mediated chronic low-grade inflammation of adipose tissue is associated with obesity and insulin resistance. Caveolin-1 (Cav-1) is the central component of adipocyte caveolae and has an essential rol
Externí odkaz:
https://doaj.org/article/0b5c2f983c054cd2a20afb36c75d5895
Autor:
Sara Palacios-Ortega, Maider Varela-Guruceaga, Fermín Ignacio Milagro, José Alfredo Martínez, Carlos de Miguel
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95100 (2014)
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of the insulin receptor (IR) and is implicated in the regulation of insulin signaling. We have found that, during adipocyte differentiation of 3T3-L1 ce
Externí odkaz:
https://doaj.org/article/de06b8f4678c43f7bf95290ee8f8968f
Autor:
Ana Patiño-García, Marc Garcia-Moure, Sonia Tejada-Solís, Marisol Gonzalez-Huarriz, Marie-Pierre Junier, Marta M. Alonso, Candelaria Gomez-Manzano, Montse Puigdelloses, Jose A. Martinez-Climent, Guillermo Aldave, Jaime Gállego Pérez-Larraya, Naiara Martinez-Velez, Hong Jiang, Luis Isaac Ramos, Maider Varela-Guruceaga, María José García-Barchino, Miguel Marigil, Hervé Chneiweiss, José Javier Aristu, Juan Fueyo, Elias A. El-Habr, Oren J. Becher, Alan Mackay, Michelle Monje, Virginia Laspidea, Marta Zalacain, Lucía Marrodán, Eric H. Raabe, Chris Jones, Ricardo Díez-Valle
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Nature Communications
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors in desperate need of a curative treatment. Oncolytic virotherapy is emerging as a solid therapeutic approach. Delta-24-RGD is a rep
Publikováno v:
Molecular and Cellular Endocrinology. 473:257-267
Obesity is characterized by hypertrophy and hyperplasia of adipose tissue, which have been related to the development of hypoxia and insulin resistance. On the other hand, caveolin-1 (Cav-1), one of the main proteins of caveolae, promotes insulin rec
Autor:
Marta M. Alonso, Jordi Bruna, Miguel Marigil, Gregorio Petrirena, Sarah Besora, Maider Varela-Guruceaga, Ricardo Díez-Valle, Jorge Nuñez, Marisol Gonzalez-Huarriz, Beatriz Zandio, Jaime Gállego Pérez-Larraya, Montserrat Puigdelloses Vallcorba, Sonia Tejada
The identification of circulating biomarkers by non-invasive methods would be helpful for glioma detection and response assessment. Strong evidences have shown that GBM cells release microvesicles containing proteins and RNA. We have previously demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b94219f58edcedc7d943a8573c0df73
https://europepmc.org/articles/PMC6217015/
https://europepmc.org/articles/PMC6217015/
Autor:
Sara Palacios-Ortega, J. Alfredo Martínez, Maider Varela-Guruceaga, Carlos de Miguel, Fermín I. Milagro
Publikováno v:
Adipocyte. 5:65-80
Adipocytes exposed to high glucose concentrations exhibit impaired metabolic function, including an increase of oxidative and proinflammatory factors that might favor the development of insulin resistance. Caveolin-1 (Cav-1) is a key mediator of the
Autor:
Ana Patiño-García, Marta M. Alonso, Candelaria Gomez-Manzano, Juan Fueyo, Maider Varela-Guruceaga, Marc Garcia-Moure, Sonia Tejada-Solís
Publikováno v:
Cancers, Vol 10, Iss 7, p 226 (2018)
Cancers
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Cancers
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
In recent years, we have seen an important progress in our comprehension of the molecular basis of pediatric brain tumors (PBTs). However, they still represent the main cause of death by disease in children. Due to the poor prognosis of some types of
Autor:
Maider Varela-Guruceaga, Marta M. Alonso, Juan Fueyo, Virginia Laspidea, Candelaria Gomez-Manzano, Marc Garcia-Moure, Marisol Gonzalez-Huarriz
Publikováno v:
Neuro-Oncology. 21:ii119-ii119
Diffuse intrinsic pontine glioma (DIPG) is an aggressive and incurable pediatric brain tumor that arises in the brainstem. The median overall survival is only one year being the standard of treatment radiotherapy. Oncolytic adenoviruses have emerged