Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Maia M. Cherney"'
Publikováno v:
Journal of Structural Biology. 178:319-328
Sulfide:quinone oxidoreductase (SQR) is a peripheral membrane protein that catalyzes the oxidation of sulfide species to elemental sulfur. The enzymatic reaction proceeds in two steps. The electrons from sulfides are transferred first to the enzyme c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d12437f119e6f95e286f8a558b34a74
https://doi.org/10.1016/j.jsb.2012.04.007
https://doi.org/10.1016/j.jsb.2012.04.007
Autor:
Dieter Brömme, Maia M. Cherney, Martin Kienitz, Zhenqiang Li, Michael N.G. James, Ferez S. Nallaseth, Fabien Lecaille
Publikováno v:
Journal of Biological Chemistry. 286:8988-8998
In the presence of oligomeric chondroitin 4-sulfate (C4-S), cathepsin K (catK) forms a specific complex that was shown to be the source of the major collagenolytic activity in bone osteoclasts. C4-S forms multiple contacts with amino acid residues on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb127ce327cf242c12011635d7e6a6cc
https://doi.org/10.1074/jbc.m110.126706
https://doi.org/10.1074/jbc.m110.126706
Publikováno v:
Journal of Medicinal Chemistry. 54:1421-1429
β-Hexosaminidases (β-hex) are a group of glycosyl hydrolase isozymes that break down neutral and sialylated glycosphingolipids in the lysosomes, thereby preventing their buildup in neuronal cells. Some mutants of β-hex have decreased folding stabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac3f0723b9b588f10a27c68276b3241
https://doi.org/10.1021/jm101443u
https://doi.org/10.1021/jm101443u
Publikováno v:
Journal of Molecular Biology. 399:240-254
The concentration of L-arginine in Mycobacterium tuberculosis (Mtb) and in many other bacteria is controlled by a transcriptional factor called the arginine repressor (ArgR). It regulates the transcription of the biosynthetic genes of the arginine op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e314926b84d102cbd2fdf6ee210a7d6
https://doi.org/10.1016/j.jmb.2010.03.065
https://doi.org/10.1016/j.jmb.2010.03.065
Autor:
Grace Garen, Craig R. Garen, Michael N.G. James, R. Sankaranarayanan, Marshall Yuan, Maia M. Cherney, Chunying Niu
Publikováno v:
Journal of Molecular Biology. 397:979-990
Mycobacterium tuberculosis ornithine acetyltransferase (Mtb OAT; E.C. 2.3.1.35) is a key enzyme of the acetyl recycling pathway during arginine biosynthesis. It reversibly catalyzes the transfer of the acetyl group from N-acetylornithine (NAORN) to l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab298251c0126bcad7e5a8a637e2ce42
https://doi.org/10.1016/j.jmb.2010.02.018
https://doi.org/10.1016/j.jmb.2010.02.018
Autor:
Matthew Solomonson, Yanfei Zhang, Maia M. Cherney, Jianshe Liu, Joel H. Weiner, Michael N.G. James
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 65:839-842
The gene product of open reading frame AFE_1293 from Acidithiobacillus ferrooxidans ATCC 23270 is annotated as encoding a sulfide:quinone oxidoreductase, an enzyme that catalyses electron transfer from sulfide to quinone. Following overexpression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf668b9d9bc7a516f9ec81e056292dab
https://doi.org/10.1107/s1744309109027535
https://doi.org/10.1107/s1744309109027535
Publikováno v:
Journal of Molecular Biology. 384:1330-1340
The arginine repressor (ArgR) from Mycobacterium tuberculosis (Mtb) is a gene product encoded by the open reading frame Rv1657. It regulates the L-arginine concentration in cells by interacting with ARG boxes in the promoter regions of the arginine b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5d9a2de1e44dd12446e9347d056739
https://doi.org/10.1016/j.jmb.2008.10.015
https://doi.org/10.1016/j.jmb.2008.10.015
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 64:805-808
The gene product of open reading frame Rv1018c from Mycobacterium tuberculosis is annotated as encoding a probable N-acetylglucosamine 1-phosphate uridylyltransferase (MtbGlmU), an enzyme that catalyzes the biosynthesis of UDP-N-acetylglucosamine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3c017be1a8b9b655bcd6795d889362
https://doi.org/10.1107/s1744309108024500
https://doi.org/10.1107/s1744309108024500
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1784:351-362
Haloalkane dehalogenases are enzymes well known to be important in bioremediation; the organisms from which they are produced are able to clean up toxic organohalides from polluted environments. However, besides being found in such contaminated envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405b2e687b73c4ad5c5d10ac4e933c04
https://doi.org/10.1016/j.bbapap.2007.10.014
https://doi.org/10.1016/j.bbapap.2007.10.014
Autor:
Craig R. Garen, Maia M. Cherney, Fatemeh Moradian, Leonid T. Cherney, Michael N.G. James, R. Sankaranarayanan
Publikováno v:
Journal of Molecular Biology. 375:1052-1063
Mycobacterium tuberculosis ornithine carbamoyltransferase (Mtb OTC) catalyzes the sixth step in arginine biosynthesis; it produces citrulline from carbamoyl phosphate (CP) and ornithine (ORN). Here, we report the crystal structures of Mtb OTC in orth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004fcc134a3f50e36936ce39274b5421
https://doi.org/10.1016/j.jmb.2007.11.025
https://doi.org/10.1016/j.jmb.2007.11.025