Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maia Azubel"'
FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
Autor:
Maia Azubel, Stephen D Carter, Jennifer Weiszmann, Jun Zhang, Grant J Jensen, Yang Li, Roger D Kornberg
Publikováno v:
eLife, Vol 8 (2019)
The fibroblast growth factor FGF21 was labeled with molecularly defined gold nanoparticles (AuNPs), applied to human adipocytes, and imaged by cryo-electron tomography (cryo-ET). Most AuNPs were in pairs about 80 Å apart, on the outer cell surface.
Externí odkaz:
https://doaj.org/article/5be575a83d7a4a18a3a1215ed7dd32df
Publikováno v:
Mol Cell
Summary Chromatin fibers must fold or coil in the process of chromosome condensation. Patterns of coiling have been demonstrated for reconstituted chromatin, but the actual trajectories of fibers in condensed states of chromosomes could not be visual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5f80c972268a7990724b71743cd6e
https://doi.org/10.1016/j.molcel.2021.08.020
https://doi.org/10.1016/j.molcel.2021.08.020
FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
Autor:
Yang Li, Roger D. Kornberg, Jennifer Weiszmann, Grant J. Jensen, Stephen D. Carter, Jun Zhang, Maia Azubel
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The fibroblast growth factor FGF21 was labeled with molecularly defined gold nanoparticles (AuNPs), applied to human adipocytes, and imaged by cryo-electron tomography (cryo-ET). Most AuNPs were in pairs about 80 Å apart, on the outer cell surface.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d22f32c8c32c4054bf15c9cf323b04f
http://europepmc.org/articles/PMC6349402
http://europepmc.org/articles/PMC6349402
Publikováno v:
ACS nano. 11(12)
Structure determination by transmission electron microscopy has revealed the long sought 144-gold atom particle. The structure exhibits deviations from face-centered cubic packing of the gold atoms, similar to the solution structure of another gold n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d97fb728586d03e24226bfdd90c28f1
https://pubmed.ncbi.nlm.nih.gov/29136369
https://pubmed.ncbi.nlm.nih.gov/29136369
Autor:
Maia Azubel, Sami Malola, Hironori Tsunoyama, Tatsuya Tsukuda, Hannu Häkkinen, David A. Bushnell, Ai Leen Koh, Jaakko Koivisto, Roger D. Kornberg, Greg L. Hura, Mika Pettersson
Publikováno v:
Science. 345:909-912
Detailed structure of a gold nanoparticle Adding only a few atoms or changing the capping ligand can dramatically change the structure of individual metal nanoparticles. Azubel et al. used aberration-corrected transmission electron microscopy to deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3e7ab61eb6e294b71870719adccd2b
https://doi.org/10.1126/science.1251959
https://doi.org/10.1126/science.1251959
Autor:
Roger D. Kornberg, Maia Azubel
Publikováno v:
Nano letters. 16(5)
By a modification of the method of Brust et al., water-soluble, thiolate-protected gold nanoparticles that are uniform in size were synthesized with no requirement for purification. The modification of the method was equilibration in the first step,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2764a72207f00bbce6b6e3e3f3b8ce64
https://pubmed.ncbi.nlm.nih.gov/27042759
https://pubmed.ncbi.nlm.nih.gov/27042759
Autor:
Brian J. Gibbons, Francisco J. Asturias, Neil R. Voss, Edward J. Brignole, Roger D. Kornberg, Maia Azubel, Kenji Murakami, David A. Bushnell
Publikováno v:
Proceedings of the National Academy of Sciences. 109:1949-1954
Structures of complete 10-subunit yeast TFIIH and of a nested set of subcomplexes, containing 5, 6, and 7 subunits, have been determined by electron microscopy (EM) and 3D reconstruction. Consistency among all the structures establishes the location
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06d6a77fba052b5693025ff47ea45b9
https://doi.org/10.1073/pnas.1105266109
https://doi.org/10.1073/pnas.1105266109
Publikováno v:
Journal of Molecular Biology. 356:955-966
Regulation of eukaryotic gene expression is achieved at different levels, which require accurate coordination. Macromolecular assemblies that exist as pre-formed entities can account for such coordination. Processing of pre-mRNA represents one step i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fb57ea7fd5939a6c11464af643cf2a
https://doi.org/10.1016/j.jmb.2005.11.078
https://doi.org/10.1016/j.jmb.2005.11.078
Autor:
Maia, Azubel, Jaakko, Koivisto, Sami, Malola, David, Bushnell, Greg L, Hura, Ai Leen, Koh, Hironori, Tsunoyama, Tatsuya, Tsukuda, Mika, Pettersson, Hannu, Häkkinen, Roger D, Kornberg
Publikováno v:
Science (New York, N.Y.). 345(6199)
Structure determination of gold nanoparticles (AuNPs) is necessary for understanding their physical and chemical properties, and only one AuNP larger than 1 nm in diameter, an Au102NP, has been solved to atomic resolution. Whereas the Au102NP structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee5e4b43b10a78b9b1d54b6df773f34c
https://pubmed.ncbi.nlm.nih.gov/25146285
https://pubmed.ncbi.nlm.nih.gov/25146285