Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Maia, Hernâni L. S."'
Autor:
Lima, Sílvia M. M. A. Pereira, Pinto, Filipa C. S. C., Ventura, Cristina, Albuquerque, Lídia, Maia, Raquel M. Gonçalves, Maia, Hernâni L. S.
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Several derivatives of N-phenylacetyl-N-benzyl-alpha,alpha-dimethylglycine cyclohexylamide and their alpha,alpha-dibenzylglycine analogues were synthesised by a Ugi-Passerini reaction. In addition, a few analogues of the former but having an N-phenyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aa173436553200553f32859ac30b195a
https://hdl.handle.net/1822/5729
https://hdl.handle.net/1822/5729
Autor:
Maia, Hernâni L. S.
History shows that Criationism has been distorting scientific arguments to justify their views which not resist to the progress of Science. If the reason and consciousness represents the more differentiated expressions of humankind and praises the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1445::33b74175fa58498d3b4d9dec21075fd6
https://hdl.handle.net/10284/784
https://hdl.handle.net/10284/784
Autor:
Maia, Hernâni L. S.
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Submitted by Leonor Sottomayor (leonor@ufp.pt) on 2008-09-26T07:49:34Z No. of bitstreams: 1 Cons-Ciencias 02.pdf: 9523653 bytes, checksum: 137c48eec61e49c0e52dc6f19f0d4cfd (MD5) Made available in DSpace on 2008-10-01T08:16:43Z (GMT). No. of bitstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3056::33b74175fa58498d3b4d9dec21075fd6
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
A general and simple strategy for routine peptide synthesis with alfa,alfa-dialkyl glycines taking advantage of the four-component Ugi-Passerini reaction is presented. The isonitrile required for the reaction can be relatively simple and its selectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7245ec05c682be6d5026fc9b0f1c4738
In recent years, our group has been involved in the use of the Ugi-Passerini reaction for the synthesis of several alpha,alpha-dialkylglycines. The C-terminal amide bond of the resulting Ugi adducts 1 proved to be very sensitive to TFA, cleaving read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______307::dfd7cd31fca6919d000d179b7c17982e
https://hdl.handle.net/1822/1931
https://hdl.handle.net/1822/1931
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
3-[(N,N-dimethylaminophenyl)-4'-diazenyl]-benzoic acid was coupled with several amino acid esters and the product further acylated with Boc. The material thus obtained was then submitted to cleavage by electrolysis and nucleophilic attack in order to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::64d1923a09ac099b3b5bb13655a5ba29
https://hdl.handle.net/1822/1952
https://hdl.handle.net/1822/1952
alpha,alpha-Dialkylglycines and their peptides have attracted considerable attention, as they show unique biological activities and very stable secondary structures. In previous work, we have reported that the amide bond at the C-terminus of a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______307::164e09e71406b7894c23637a1bee7593
https://hdl.handle.net/1822/1974
https://hdl.handle.net/1822/1974
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Synthetic and spectroscopic details related to a set of heteroaromatic N-benzyl carboxamides and especially the corresponding tert-butyl acylcarbamates are reported. These compounds were required to study the postulated effect of various heterocycles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7ace452acceb589ff77551eb7503dcd3
Owing to steric hindrance, syntheses of and reactions with alfa,alfa-dialkylglycines are very slow; thus, most methods of peptide synthesis are of little use to handle these compounds when the alfa-alkyl groups are larger than methyl. Ugi’s four-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______307::70941011c4ca69f4dc7774073c35af68
https://hdl.handle.net/1822/2072
https://hdl.handle.net/1822/2072
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Michael additions of nitrogen heterocycles, thiols, carbon nucleophiles and amines to dehydroalanine derivatives, including a glycyldehydroalanine peptide, were performed in fair to good yields. Dehydroaminobutyric acid derivatives reacted only with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5ff5708c86fed436c62051cd7ac01d9b
https://hdl.handle.net/1822/2196
https://hdl.handle.net/1822/2196