Adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype (LAST ACT): Study protocol for a randomised double blind placebo controlled non-inferiority trial.

Autor: Donovan J; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Phu NH; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Thao LTP; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Lan NH; Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam., Mai NTH; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Trang NTM; Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam., Hiep NTT; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Nhu TB; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Hanh BTB; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Mai VTP; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Bang ND; Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam., Giang DC; Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam., Ha DTM; Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam., Day J; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Thuong NT; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Vien NN; Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam., Geskus RB; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Hien TT; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Kestelyn E; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Wolbers M; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Chau NVV; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Thwaites GE; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Publikováno v: Wellcome open research [Wellcome Open Res] 2018 Mar 20; Vol. 3, pp. 32. Date of Electronic Publication: 2018 Mar 20 (Print Publication: 2018).