Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mai Takizawa"'
Autor:
Mai Takizawa, Yuri Osuga, Rika Ishida, Marie Mita, Kazuki Harada, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
A red fluorescent protein-based indicator of cyclic guanosine 3′, 5′-monophosphate (cGMP) allows for multi-colour imaging and optogenetic applications while monitoring cGMP activity in cells.
Externí odkaz:
https://doaj.org/article/8235020990e142d49fc77db5453efb48
Autor:
Marie Mita, Mary Arai, Yuki Hayasaka, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi, Saki Tsuno, Mitsuharu Matsumoto, Mai Takizawa, Takami Chihara, Takeshi Ishihara, Kentaro Ishida, K Harada
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Glycolysis is the metabolic pathway that converts glucose into pyruvate, whereas fermentation can then produce lactate from pyruvate. Here, we developed single fluorescent protein (FP)-based lactate and pyruvate indicators with low EC50 for trace det
Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics
Autor:
Motoki Ito, Marie Mita, K Harada, Tetsuya Kitaguchi, Hiroshi Ueda, Takashi Tsuboi, Mai Takizawa, Kentaro Ishida, Izumi Sugawara
Publikováno v:
Cell chemical biology. 29(1)
Summary Glucose is the main source of energy for organisms, and it is important to understand the spatiotemporal dynamics of intracellular glucose. Single fluorescent protein-based glucose indicators, named “Red Glifons” have been developed that
Autor:
Tadafumi Kato, Takumi Nakamura, Kunihiro Ohta, Tetsuya Kitaguchi, Kazuki Harada, Taichi Kamiya, Jim Küppers, Kazuo Nakajima, Mai Takizawa, Michael Gütschow, Takashi Tsuboi
Publikováno v:
Journal of molecular endocrinology. 64(3)
Glucagon-like peptide-1 (GLP-1), secreted by gastrointestinal enteroendocrine L cells, induces insulin secretion and is important for glucose homeostasis. GLP-1 secretion is induced by various luminal nutrients, including amino acids. Intracellular C
Autor:
Devina Wongso, Shogo Matsuda, Tetsuya Kitaguchi, Takashi Tsuboi, Motoki Ito, Mai Takizawa, Kazuki Harada
Publikováno v:
ACS Sensors. 2:46-51
Here we describe the development of a single fluorescent protein (FP)-based cGMP indicator, Green cGull, based on the cGMP binding domain from mouse phosphodiesterase 5α. The dynamic range of Green cGull was enhanced to a 7.5-fold fluorescence chang
Publikováno v:
Biochemical and biophysical research communications. 501(4)
Astrocytes, a large population of glial cells, detect neurotransmitters and respond by increasing intracellular Ca2+ concentration ([Ca2+]i) and releasing chemical molecules called gliotransmitters. Recently discovered Ca2+ influx through transient r
Publikováno v:
Biochemical and biophysical research communications. 501(4)
S-equol is one of gut bacterial metabolites produced from soybean isoflavone daizein. While S-equol is known to promote glucose-induced insulin secretion from pancreatic β cells, whether S-equol affects glucagon-like peptide-1 (GLP-1) secretion from
Autor:
Takumi Nakamura1,2, Kazuki Harada1, Taichi Kamiya1, Mai Takizawa1, Jim Küppers3, Kazuo Nakajima2, Gütschow, Michael3, Tetsuya Kitaguchi4, Kunihiro Ohta1, Tadafumi Kato2, Takashi Tsuboi1 takatsuboi@bio.c.u-tokyo.ac.jp
Publikováno v:
Journal of Molecular Endocrinology. Apr2020, Vol. 64 Issue 3, p133-143. 11p.