Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mai Izumida"'
Autor:
Mai Izumida, Haddijatou Jobe, Edward G. Coker, Amadou Barry, Momodou Rashid, Ismaila L. Manneh, Georgetta K. Daffeh, Koya Ariyoshi, Jayne S. Sutherland
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundTo effectively control tuberculosis (TB), it is crucial to distinguish between active TB disease and latent TB infection (LTBI) to provide appropriate treatment. However, no such tests are currently available. Immune responses associated wi
Externí odkaz:
https://doaj.org/article/4ce0e46d2610480a9ee71f3f4b64e080
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Gene editing using CRISPR/Cas9 is a promising method to cure many human genetic diseases. We have developed an efficient system to deliver Cas9 into the adeno-associated virus integration site 1 (AAVS1) locus, known as a safe harbor, using l
Externí odkaz:
https://doaj.org/article/fce61c5bca0b424ab95f614d32a7cd92
Autor:
Yasuhiro Tanaka, Kazuko Yamamoto, Shimpei Morimoto, Takeshi Nabeshima, Kayoko Matsushima, Hiroshi Ishimoto, Nobuyuki Ashizawa, Tatsuro Hirayama, Kazuaki Takeda, Hiroshi Gyotoku, Naoki Iwanaga, Shinnosuke Takemoto, Susumu Fukahori, Takahiro Takazono, Hiroyuki Yamaguchi, Takashi Kido, Noriho Sakamoto, Naoki Hosogaya, Shogo Akabame, Takashi Sugimoto, Hirotomo Yamanashi, Kosuke Matsui, Mai Izumida, Ayumi Fujita, Masato Tashiro, Takeshi Tanaka, Koya Ariyoshi, Akitsugu Furumoto, Kouichi Morita, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 18, p 5444 (2022)
Managing mild illness in COVID-19 and predicting progression to severe disease are concerning issues. Here, we investigated the outcomes of Japanese patients with mild COVID-19, and identified triage risk factors for further hospitalization and emerg
Externí odkaz:
https://doaj.org/article/7f370c8fe9834dc5b4539ad8b5d05610
Publikováno v:
Cells, Vol 11, Iss 14, p 2240 (2022)
Gamma-interferon (γ-IFN) significantly inhibits infection by replication-defective viral vectors derived from the human immunodeficiency virus type 1 (HIV-1) or murine leukemia virus (MLV) but the underlying mechanism remains unclear. Previously we
Externí odkaz:
https://doaj.org/article/3f86258eefbf4fe390843d760099f35a
Autor:
Mai Izumida, Osamu Kotani, Hideki Hayashi, Chris Smith, Tsutomu Fukuda, Koushirou Suga, Masatomo Iwao, Fumito Ishibashi, Hironori Sato, Yoshinao Kubo
Publikováno v:
Viruses, Vol 14, Iss 4, p 816 (2022)
Lamellarin α 20-sulfate is a cell-impenetrable marine alkaloid that can suppress infection that is mediated by the envelope glycoprotein of human immunodeficiency virus type 1. We explored the antiviral action and mechanisms of this alkaloid against
Externí odkaz:
https://doaj.org/article/6ca6edef37b7450e8dbc2bc0a5a15488
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Human immunodeficiency virus type 1 (HIV-1)-based viral vector is widely used as a biomaterial to transfer a gene of interest into target cells in many biological study fields including gene therapy. Vesicular stomatitis virus glycoprotein (VSV-G)-co
Externí odkaz:
https://doaj.org/article/397366b406a6434aa0ce152adccd7404
Publikováno v:
Viruses, Vol 12, Iss 7, p 722 (2020)
Chikungunya virus (CHIKV) is an enveloped virus that enters host cells and transits within the endosomes before starting its replication cycle, the precise mechanism of which is yet to be elucidated. Endocytosis and endosome acidification inhibitors
Externí odkaz:
https://doaj.org/article/650de6b4a2ad4203a6321d11978398f6
Autor:
Haruka Kamiyama, Mai Izumida, Yuria Umemura, Hideki Hayashi, Toshifumi Matsuyama, Yoshinao Kubo
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion rele
Externí odkaz:
https://doaj.org/article/c00909b3e4e442b2a67310cd8cdda2c4
Autor:
Hideki Hayashi, Yoshinao Kubo, Mai Izumida, Etsuhisa Takahashi, Hiroshi Kido, Ko Sato, Mutsuo Yamaya, Hidekazu Nishimura, Kou Nakayama, Toshifumi Matsuyama
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Cleavage and activation of hemagglutinin (HA) by trypsin-like proteases in influenza A virus (IAV) are essential prerequisites for its successful infection and spread. In host cells, some transmembrane serine proteases such as TMPRSS2, TMPRSS4 and HA
Externí odkaz:
https://doaj.org/article/4841b54749e4442dbba80f6077e6936f
Autor:
Yoshinao Kubo, Hiroshi Masumoto, Mai Izumida, Katsura Kakoki, Hideki Hayashi, Toshifumi Matsuyama
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
CD63, a member of the tetraspanin family, is involved in virion production by human immunodeficiency virus type 1 (HIV-1), but its mechanism is unknown. In this study, we showed that a small GTP-binding protein, Rab3a, interacts with CD63. When Rab3a
Externí odkaz:
https://doaj.org/article/9e390a18fc4b409ab022a3a4b6496032