Výsledky vyhledávání

Transcriptional Regulation of the Membrane-associated Prostaglandin E2 Synthase Gene

Autor: Naomi Tago, Tadashi Tanabe, Hiroaki Naraba, Chieko Yokoyama, Makoto Murakami, Mai Fueki, Sachiko Oh-ishi, Ichiro Kudo

Publikováno v: Journal of Biological Chemistry. 277:28601-28608

Membrane-associated prostaglandin (PG) E2 synthase (mPGES) is an inducible terminal enzyme in the biosynthetic pathway for prostaglandin E2, which participates in many biological processes. In this study, we investigated the molecular mechanism contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9cbb3493d0221f5f6dac95573e4ebd77
https://doi.org/10.1074/jbc.m203618200

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Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1

Autor: Hiroaki, Naraba, Chieko, Yokoyama, Naomi, Tago, Makoto, Murakami, Ichiro, Kudo, Mai, Fueki, Sachiko, Oh-Ishi, Tadashi, Tanabe

Publikováno v: The Journal of biological chemistry. 277(32)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc1afcf30c6156f3c08d45b00a32c758
https://pubmed.ncbi.nlm.nih.gov/12034740

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Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

Autor: Sachiko Oh-ishi, Fumiaki Kojima, Yoshihito Nakatani, Ichiro Kudo, Hiroaki Naraba, Toshihiro Tanioka, Akinori Ueno, Makoto Murakami, Natsuki Semmyo, Mai Fueki, Tomomi Ikeda

Publikováno v: The Journal of biological chemistry. 275(42)

Here we report the molecular identification of membrane-bound glutathione (GSH)-dependent prostaglandin (PG) E(2) synthase (mPGES), a terminal enzyme of the cyclooxygenase (COX)-2-mediated PGE(2) biosynthetic pathway. The activity of mPGES was increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a2f3267d4d07df18e83f866ed241ff
https://pubmed.ncbi.nlm.nih.gov/10869354

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Analysis of the AP-1 activation in the signal transduction pathway of bradykinin agonists in the bradykinin-receptor over-expressed HEK293 cells

Autor: Akinori Ueno, Hiroaki Naraba, Mineka Yoshimura, Mai Fueki, Sachiko Oh-ishi

Publikováno v: Japanese Journal of Pharmacology. 79:88

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::059953011bad238049dda47bc2445eeb
https://doi.org/10.1016/s0021-5198(19)34377-x

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