Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Mai Britt Zocca"'
Autor:
Inés Lecoq, Katharina L. Kopp, Marion Chapellier, Panagiotis Mantas, Evelina Martinenaite, Maria Perez-Penco, Lars Rønn Olsen, Mai-Britt Zocca, Ayako Wakatsuki Pedersen, Mads Hald Andersen
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
CCL22 is a macrophage-derived immunosuppressive chemokine that recruits regulatory T cells through the CCL22:CCR4 axis. CCL22 was shown to play a key role in suppressing anti-cancer immune responses in different cancer types. Recently, we showed that
Externí odkaz:
https://doaj.org/article/4deb28186bcd4fa28e4ce8cd2df20145
Autor:
Mads Hald Andersen, Souvik Dey, Erika Sutanto-Ward, Katharina L Kopp, James DuHadaway, Arpita Mondal, Dema Ghaban, Inés Lecoq, Mai-Britt Zocca, Lauren M F Merlo, Laura Mandik-Nayak, Ayako Wakatsuki Pedersen, Alexander J Muller
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase 1 (IDO1), which subverts T-cell immunity at multiple levels, is itself subject to inherent T-cell reactivity. This intriguing deviation from central tolerance has been interpre
Externí odkaz:
https://doaj.org/article/85b92312e7ef499e81e377e49eedf1d5
Autor:
Samir N. Khleif, Seema Gupta, Mikayel Mkrtichyan, Mai-Britt Zocca, Ayako Wakatsuki Pedersen, Mads Hald Andersen, Nour Shobaki, Zainab Ramlaoui, Xingdong Yang, Veerupaxagouda Patil, Pankaj Gaur, Vivek Verma, Rahul Nandre
Supplementary Figure from IDO Vaccine Ablates Immune-Suppressive Myeloid Populations and Enhances Antitumor Effects Independent of Tumor Cell IDO Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edd7ca342d91a9cef7de4a043847aee
https://doi.org/10.1158/2326-6066.22544379.v1
https://doi.org/10.1158/2326-6066.22544379.v1
Autor:
Mads Hald Andersen, Vincenzo Bronte, Ayako Wakatsuki Pedersen, Daniel Hargbøll Madsen, Mai-Britt Zocca, Manuela Iezzi, Cristina Frusteri, Francesco De Sanctis, Annalisa Adamo, Marion Chapellier, Katharina Kopp, Evelina Martinenaite, Stine Emilie Weis-Banke, Maria Perez-Penco, Marco Carretta, Mie Linder Hübbe, Stefano Ugel, Mia Aaboe Jørgensen
Expression of the L-arginine catabolizing enzyme arginase 1 (ARG1) is a central immunosuppressive mechanism mediated by tumor-educated myeloid cells. Increased activity of ARG1 promotes the formation of an immunosuppressive microenvironment and leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666a35b5cf78d8cf2f4835377ed3e14d
https://doi.org/10.1158/2326-6066.c.6550574
https://doi.org/10.1158/2326-6066.c.6550574
Autor:
Samir N. Khleif, Seema Gupta, Mikayel Mkrtichyan, Mai-Britt Zocca, Ayako Wakatsuki Pedersen, Mads Hald Andersen, Nour Shobaki, Zainab Ramlaoui, Xingdong Yang, Veerupaxagouda Patil, Pankaj Gaur, Vivek Verma, Rahul Nandre
The immunosuppressive tumor microenvironment (TME) does not allow generation and expansion of antitumor effector cells. One of the potent immunosuppressive factors present in the TME is the indoleamine-pyrrole 2,3-dioxygenase (IDO) enzyme, produced m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ee05cf106a5bc42dc9b17ba076c0e8
https://doi.org/10.1158/2326-6066.c.6550626
https://doi.org/10.1158/2326-6066.c.6550626
Autor:
Mogens H. Claesson, Mai-Britt Zocca, Wen Hsin Koo, Simon Ong, Kian Fong Foo, Siew Wan Hee, Sze Huey Tan, Yatanar Soe, Yee Peng Phoon, Kelly Teo, Li Sun, Pia Kvistborg, Whay Kuang Chia, Who-Whong Wang, Han Chong Toh
Supplementary Data from Clinical Benefit of Allogeneic Melanoma Cell Lysate–Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a128b0560ab3af157da1a7ac342aa74
https://doi.org/10.1158/1078-0432.22440432
https://doi.org/10.1158/1078-0432.22440432
Autor:
Mogens H. Claesson, Mai-Britt Zocca, Wen Hsin Koo, Simon Ong, Kian Fong Foo, Siew Wan Hee, Sze Huey Tan, Yatanar Soe, Yee Peng Phoon, Kelly Teo, Li Sun, Pia Kvistborg, Whay Kuang Chia, Who-Whong Wang, Han Chong Toh
Purpose: We evaluated the clinical benefit of an allogeneic melanoma cell lysate (MCL)–pulsed autologous dendritic cell (DC) vaccine in advanced colorectal cancer patients expressing at least one of six MAGE-A antigens overexpressed by the cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0053dc32781966b8265ef9c77bd5e5
https://doi.org/10.1158/1078-0432.c.6517761
https://doi.org/10.1158/1078-0432.c.6517761
Autor:
Rahul Nandre, Vivek Verma, Pankaj Gaur, Veerupaxagouda Patil, Xingdong Yang, Zainab Ramlaoui, Nour Shobaki, Mads Hald Andersen, Ayako Wakatsuki Pedersen, Mai-Britt Zocca, Mikayel Mkrtichyan, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Immunology Research. 10:571-580
The immunosuppressive tumor microenvironment (TME) does not allow generation and expansion of antitumor effector cells. One of the potent immunosuppressive factors present in the TME is the indoleamine-pyrrole 2,3-dioxygenase (IDO) enzyme, produced m
Publikováno v:
Clinical Cancer Research. 27:689-703
Therapeutic cancer vaccines, an exciting development in cancer immunotherapy, share the goal of creating and amplifying tumor-specific T-cell responses, but significant obstacles still remain to their success. Here, we briefly outline the principles
Autor:
Evelina Martinenaite, Annalisa Adamo, Stine Emilie Weis-Banke, Katharina L. Kopp, Maria Perez-Penco, Stefano Ugel, Marion Chapellier, Vincenzo Bronte, Mie Linder Hübbe, Cristina Frusteri, Marco Carretta, Mia Aaboe Jørgensen, Mai-Britt Zocca, Francesco De Sanctis, Ayako Wakatsuki Pedersen, Manuela Iezzi, Mads Hald Andersen, Daniel Hargbøll Madsen
Publikováno v:
Cancer immunology research. 9(11)
Expression of the L-arginine catabolizing enzyme arginase 1 (ARG1) is a central immunosuppressive mechanism mediated by tumor-educated myeloid cells. Increased activity of ARG1 promotes the formation of an immunosuppressive microenvironment and leads