Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mai A. Galal"'
Publikováno v:
Molecules, Vol 17, Iss 6, Pp 7217-7231 (2012)
A series of new thiophene derivatives has been synthesized using the Gewald protocol. The acetylcholinesterase inhibition activity was assayed according to Ellman’s method using donepezil as reference. Some of the compounds were found to be more po
Externí odkaz:
https://doaj.org/article/7b9960c6e5a9465b8ebabe4e6b1746ff
Publikováno v:
Drug Development Research. 83:1394-1407
A series of tetrahydrobenzothienopyrimidines and tetrahydrobenzothienotriazines incorporating a pharmacophore from donepezil molecule were designed and synthesized. The 12 newly synthesized compounds were screened for their inhibition activity agains
Publikováno v:
Molecular Neurobiology. 54:5074-5084
Vascular dementia (VaD) is a degenerative cerebrovascular disorder that leads to progressive decline in cognitive abilities and memory. Several reports demonstrated that oxidative stress and endothelial dysfunction are principal pathogenic factors in
Publikováno v:
Molecules; Volume 17; Issue 6; Pages: 7217-7231
Molecules
Molecules, Vol 17, Iss 6, Pp 7217-7231 (2012)
Molecules
Molecules, Vol 17, Iss 6, Pp 7217-7231 (2012)
A series of new thiophene derivatives has been synthesized using the Gewald protocol. The acetylcholinesterase inhibition activity was assayed according to Ellman’s method using donepezil as reference. Some of the compounds were found to be more po