Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mai A. Al-Mohanna"'
Autor:
Mohsen Mahmoud, Mady, Fatima Hasan, Al-Shaikh, Faridah Farhan, Al-Farhan, Amany Abdullah, Aly, Mai Abdullah, Al-Mohanna, Magdy Mohammed, Ghannam
Publikováno v:
Pakistan journal of pharmaceutical sciences. 28
Treatment with doxorubicin (DOX) is a common treatment for different types of cancer. DOX-NP is one of a well established marketed liposomal formulation for DOX. It has advantages over free DOX in reducing the cardiac toxicity and increasing the effi
Publikováno v:
Nucleic Acids Research
p16INK4a and p21WAF1, two major cyclin-dependent kinase inhibitors, are the products of two tumor suppressor genes that play important roles in various cellular metabolic pathways. p21WAF1 is up-regulated in response to different DNA damaging agents.
Autor:
Abdelilah Aboussekhra, Mai A. Al-Mohanna, Zuha Al-Mukhalafi, Khaled Al-Hussein, Pulicat S. Manogaran
Publikováno v:
Oncogene. 23(1)
p16(INK4a) (hereafter referred to as p16), a major cyclin-dependent kinase (CDK) inhibitor, is the product of a tumor-suppressor gene that has been found inactivated in different cancer types. In the present study, we sought to investigate the role o
Autor:
Per-Anders Bertilsson, Abdelilah Aboussekhra, Zbigniew Krezolek, Khalid A. Al-Houssein, Mai A. Al-Mohanna, Fahad M. Al-Khodairy
Publikováno v:
Carcinogenesis. 22(4)
Genotoxic agents, including gamma-rays and UV light, induce transient arrest at different phases of the cell cycle. These arrests are required for efficient repair of DNA lesions, and employ several factors, including the product of the tumor suppres