Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mahyar Sabripour"'
Autor:
Lulu Huang, Sagar S Damle, Sheri Booten, Priyam Singh, Mahyar Sabripour, Jeff Hsu, Minji Jo, Melanie Katz, Andy Watt, Christopher E Hart, Susan M Freier, Brett P Monia, Shuling Guo
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132798 (2015)
Liver regeneration after partial hepatectomy (PHx) is a complex and well-orchestrated biological process in which synchronized cell proliferation is induced in response to the loss of liver mass. To define long noncoding RNAs (lncRNAs) that participa
Externí odkaz:
https://doaj.org/article/6cb40089f7c54364ba90740f1b4158a0
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e29429 (2012)
BACKGROUND: Wig-1 is a transcription factor regulated by p53 that can interact with hnRNP A2/B1, RNA Helicase A, and dsRNAs, which plays an important role in RNA and protein stabilization. in vitro studies have shown that wig-1 binds p53 mRNA and sta
Externí odkaz:
https://doaj.org/article/a15874f91c2c47859c2a12b62e01b643
Publikováno v:
OncoImmunology. 1:773-776
Imatinib revolutionized gastrointestinal stromal tumor (GIST) treatment but median-progression-free-survival of unresectable/metastatic disease is < 2 y. B-RAFV600-mutated-melanoma responds to vemurafenib dramatically but median-progression-free-surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841b28e53f39ee08d9d1dd735db9f2ea
https://doi.org/10.4161/onci.19729
https://doi.org/10.4161/onci.19729
Autor:
Thazha P. Prakash, Husam S. Younis, Susan M. Freier, Melanie Katz, Stanley T. Crooke, C. Frank Bennett, Todd Machemer, Sebastien A. Burel, Huynh-Hoa Bui, Christopher E. Hart, Eric E. Swayze, Andrew T. Watt, Patrick Cauntay, Punit P. Seth, Mahyar Sabripour, Jill Hsiao, Scott P. Henry, Amy Dan, Gene Hung
Publikováno v:
Nucleic Acids Research
High affinity antisense oligonucleotides (ASOs) containing bicylic modifications (BNA) such as locked nucleic acid (LNA) designed to induce target RNA cleavage have been shown to have enhanced potency along with a higher propensity to cause hepatotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84634983f76ef18c0683f4653d66581
https://pubmed.ncbi.nlm.nih.gov/26553810
https://pubmed.ncbi.nlm.nih.gov/26553810
Autor:
Brett P. Monia, Sagar S. Damle, Minji Jo, Andrew T. Watt, Priyam Singh, Jeff Hsu, Shuling Guo, Sheri L. Booten, Melanie Katz, Susan M. Freier, Christopher E. Hart, Lulu Huang, Mahyar Sabripour
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0132798 (2015)
PLoS ONE, Vol 10, Iss 7, p e0132798 (2015)
Liver regeneration after partial hepatectomy (PHx) is a complex and well-orchestrated biological process in which synchronized cell proliferation is induced in response to the loss of liver mass. To define long noncoding RNAs (lncRNAs) that participa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b272f6098e543afd10f0a0131b3487
http://europepmc.org/articles/PMC4514479
http://europepmc.org/articles/PMC4514479
Autor:
Mahyar Sabripour, Eitan Friedman, M. B. Keitheri-Cheteri, Michael F. Seldin, Chongjuan Wei, Christopher I. Amos, Patrick M. Lynch, Marsha L. Frazier, H. H. Fidder, Thomas J. McGarrity, L. Nations
Publikováno v:
Journal of Medical Genetics. 41:327-333
Background and aims: Peutz-Jeghers syndrome (PJS) is a dominantly inherited disorder often caused by mutations in STK11. Time to onset of symptoms was characterised for a large collection of individuals with PJS who had been tested for STK11 mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5981e3d1d66734404f4b46455109525b
https://doi.org/10.1136/jmg.2003.010900
https://doi.org/10.1136/jmg.2003.010900
Autor:
Mahyar Sabripour, Asif Rashid, Thomas J. McGarrity, Chongjuan Wei, Christopher I. Amos, Linda Nations, Marsha L. Frazier
Publikováno v:
Journal of Histochemistry & Cytochemistry. 51:1665-1672
Germline mutations of the LKB1 gene lead to Peutz-Jeghers syndrome (PJS), which is associated with a predisposition to gastrointestinal polyposis and cancer. In this study we tested for germline mutations of LKB1 in 11 patients with PJS from nine fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb04c1c1749101e5ca1c458c35b6fe4c
https://doi.org/10.1177/002215540305101210
https://doi.org/10.1177/002215540305101210
Publikováno v:
Nature reviews. Genetics. 7(1)
In just a few years, microarrays have gone from obscurity to being almost ubiquitous in biological research. At the same time, the statistical methodology for microarray analysis has progressed from simple visual assessments of results to a weekly de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32779ad6f40a24b504bc23da93a17d2a
https://pubmed.ncbi.nlm.nih.gov/16369572
https://pubmed.ncbi.nlm.nih.gov/16369572
Autor:
Shreyaskumar Patel, Barry W. Feig, Robert H.I. Andtbacka, Marsha L. Frazier, Elsie F. Wu, Robert S. Benjamin, Lei L. Chen, Mahyar Sabripour, Homer A. Macapinlac, Haesun Choi
Publikováno v:
Current oncology reports. 7(4)
Conventional chemotherapeutic drugs are ineffective in treatment of gastrointestinal stromal tumors (GISTs). Imatinib (STI571, Gleevec, Glivec; Novartis Pharmaceuticals, East Hanover, NJ), a selective inhibitor of KIT, ABL, BCR-ABL, PDGFRA, and PDGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed194fb03e8e869b57aefae0d9018490
https://pubmed.ncbi.nlm.nih.gov/15946589
https://pubmed.ncbi.nlm.nih.gov/15946589
Autor:
Elsie F. Wu, Mahyar Sabripour, Gregory N. Fuller, Marsha L. Frazier, Lei L. Chen, Victor G. Prieto
Publikováno v:
Oncogene. 24(26)
We report a new mechanism of aberrant pre-mRNA splicing resulting in constitutive activation of a mis-spliced oncoprotein (KIT) leading to malignancy (gastrointestinal stromal tumor) in contrast to loss of function of mis-spliced proteins resulting i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b2f20120f0ef78f5206ecc2b9e3dad
https://pubmed.ncbi.nlm.nih.gov/15824741
https://pubmed.ncbi.nlm.nih.gov/15824741