Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Mahvash Tavassoli"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Head and neck squamous cell carcinomas (HNSCCs) are amongst the most aggressive, complex, and heterogeneous malignancies. The standard of care treatments for HNC patients include surgery, radiotherapy, chemotherapy, or their combination. How
Externí odkaz:
https://doaj.org/article/05735605af9442e1a4d861b871f8a6ff
Autor:
Luise Dunsche, Nikita Ivanisenko, Shamala Riemann, Sebastian Schindler, Stefan Beissert, Cristian Angeli, Stephanie Kreis, Mahvash Tavassoli, Inna Lavrik, Dagmar Kulms
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-12 (2023)
Abstract Malignant melanoma (MM) is known to be intrinsically chemoresistant, even though only ~20% of MM carry mutations of the tumor suppressor p53. Despite improvement of systemic therapy the mortality rate of patients suffering from metastatic MM
Externí odkaz:
https://doaj.org/article/a2981f85ff5e4563ac4ee7b07352b383
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-13 (2022)
Abstract EGFR upregulation is an established biomarker of treatment resistance and aggressiveness in head and neck cancers (HNSCC). EGFR-targeted therapies have shown benefits for HPV-negative HNSCC; surprisingly, inhibiting EGFR in HPV-associated HN
Externí odkaz:
https://doaj.org/article/8e20b4dece594dba9b92f0cf1b3ab371
Publikováno v:
Molecular Oncology, Vol 12, Iss 12, Pp 2023-2041 (2018)
Head and neck squamous cell carcinomas (HNSCC) are associated with poor morbidity and mortality. Current treatment strategies are highly toxic and do not benefit over 50% of patients. There is therefore a crucial need for predictive and/or prognostic
Externí odkaz:
https://doaj.org/article/86f1109b229f4b6689cb2a1d53b1d8ee
Autor:
James W Opzoomer, Jessica A Timms, Kevin Blighe, Thanos P Mourikis, Nicolas Chapuis, Richard Bekoe, Sedigeh Kareemaghay, Paola Nocerino, Benedetta Apollonio, Alan G Ramsay, Mahvash Tavassoli, Claire Harrison, Francesca Ciccarelli, Peter Parker, Michaela Fontenay, Paul R Barber, James N Arnold, Shahram Kordasti
Publikováno v:
eLife, Vol 10 (2021)
High-dimensional cytometry is an innovative tool for immune monitoring in health and disease, and it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases. However, the analysis of large multiparametri
Externí odkaz:
https://doaj.org/article/78033dd608be40de9a83b21d8e652c8c
Autor:
Victoria L. Codony, Mahvash Tavassoli
Publikováno v:
Translational Oncology, Vol 14, Iss 3, Pp 101017- (2021)
Most solid tumors, such as head and neck cancers, feature a hypoxic microenvironment due to angiogenic dysregulation and the consequent disruption of their vascular network. Such nutrient-deprived environment can induce genomic changes in several tum
Externí odkaz:
https://doaj.org/article/ff836c100e2c4c129cd61b5e41ead265
Autor:
Angela Stokes, Ignat Drozdov, Eliete Guerra, Christos A Ouzounis, Saman Warnakulasuriya, Michael J Gleeson, Mark McGurk, Mahvash Tavassoli, Edward W Odell
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24503 (2011)
The requirement for large amounts of good quality DNA for whole-genome applications prohibits their use for small, laser capture micro-dissected (LCM), and/or rare clinical samples, which are also often formalin-fixed and paraffin-embedded (FFPE). Wh
Externí odkaz:
https://doaj.org/article/1fa7af9016324d65942efae4a73ac254
Publikováno v:
Chemical Science. 14:3881-3892
Structure-activity studies with site-specifically modified apoptin in living cells demonstrate that this protein's toxicity is mediated by phosphorylation and downstream interactions with the cytoskeleton.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbaddb769178eb38fcb80d9a8ff64206
https://doi.org/10.1039/d2sc04481a
https://doi.org/10.1039/d2sc04481a
Autor:
Joop Gäken, Mahvash Tavassoli, Ghulam Mufti, Farzin Farzaneh, Lee Macpherson, Nigel Westwood, Daryl Cole, Jie Jiang
Supplementary Figure 1 from Crucial Roles for Protein Kinase C Isoforms in Tumor-Specific Killing by Apoptin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670be585554ae281a4e2c270949082c
https://doi.org/10.1158/0008-5472.22385171.v1
https://doi.org/10.1158/0008-5472.22385171.v1
Autor:
Joop Gäken, Mahvash Tavassoli, Ghulam Mufti, Farzin Farzaneh, Lee Macpherson, Nigel Westwood, Daryl Cole, Jie Jiang
The chicken anemia virus–derived protein apoptin induces apoptosis in a variety of human malignant and transformed cells but not in normal cells. However, the mechanisms through which apoptin achieves its selective killing effects are not well unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b03cf6fafae6f31c04b17ade6eff50f
https://doi.org/10.1158/0008-5472.c.6501128.v1
https://doi.org/10.1158/0008-5472.c.6501128.v1