Výsledky vyhledávání - "Mahsa Toolabi"

Akademický článek

Synthesis, α-Glucosidase inhibitory activity and docking studies of Novel Ethyl 1,2,3-triazol-4-ylmethylthio-5,6-diphenylpyridazine-4-carboxylate derivatives

Autor: Loghman Firoozpour, Setareh Moghimi, Somayeh Salarinejad, Mahsa Toolabi, Mahdi Rafsanjani, Roya Pakrad, Farzaneh Salmani, Seyed Mohammad Shokrolahi, Seyed Esmail Sadat Ebrahimi, Saeed Karima, Alireza Foroumadi

Publikováno v: BMC Chemistry, Vol 17, Iss 1, Pp 1-10 (2023)

Abstract In this work, a novel series of pyridazine-triazole hybrid molecules were prepared and evaluated as inhibitors of rat intestinal α-glucosidase enzyme. Amongst all newly synthesized compounds, 10k showed good inhibition in the series with IC

Externí odkaz: https://doaj.org/article/c30599aa34a441b394c7777d3e7aeaf9

Zobrazit plný text záznamu

Plný text ve formátu HTML

Design, synthesis, and biological evaluation of 1-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-3-phenylurea derivatives as anticancer agents

Autor: Adileh Ayati, Tayebeh Oghabi Bakhshaiesh, Mahsa Toolabi, Rezvan Esmaeili, Elahe Nazeri, Loghman Firoozpour, Alireza Foroumadi, Ayoub Aghcheli, Maryam Norouzbahari, Setareh Moghimi

Publikováno v: Medicinal Chemistry Research. 29:2000-2010

A novel series of 1-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-3-phenylurea derivatives (5a–l) were designed and synthesized as sorafenib analogs. The in vitro cytotoxicity effects of synthesized compounds were evaluated against four different human ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84bfec1c3526e0d5780f813bac51c82c
https://doi.org/10.1007/s00044-020-02616-2

Zobrazit plný text záznamu

Synthesis and activity evaluation of new benzofuran-1,3,4-oxadiazole hybrids against wood-degrading fungi

Autor: Seyyed Khalil Hosseinihashemi, Mahsa Toolabi, Fahimeh Abedinifar, Setareh Moghimi, Abbas Jalaligoldeh, Farzad Paknejad, Shahrbanoo Arabahmadi, Alireza Foroumadi

Publikováno v: BioResources. 15:1085-1097

A series of novel benzofuran-1,3,4-oxadiazole hybrids were synthesized and evaluated as antifungal agents. The synthetic pathway was started from salicylaldehyde, which afforded 5-(substituted benzylthio)-1,3,4-oxadiazole derivatives in moderate to g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbd78d7f067c2c7e52a063005e33aaf3
https://doi.org/10.15376/biores.15.1.1085-1097

Zobrazit plný text záznamu

Design and synthesis of benzodiazepine-1,2,3-triazole hybrid derivatives as selective butyrylcholinesterase inhibitors

Autor: Mahsa Toolabi, Fereshteh Goli, Mahdi Hassankalhori, Hamid Nadri, Alireza Foroumadi, Loghman Firoozpour, Setareh Moghimi, Mehrdad Mehrazar, Syed Nasir Abbas Bukhari

Publikováno v: Molecular Diversity. 24:997-1013

A new series of compounds based on benzodiazepine-1,2,3-triazole were synthesized and evaluated as cholinesterase inhibitors by Ellman’s method. The compounds proved to be selective inhibitors of butyrylcholinesterase (BuChE) over acetylcholinester

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5f3492ba3a604cbe6dc5dafedfbd5e
https://doi.org/10.1007/s11030-019-10008-x

Zobrazit plný text záznamu

Synthesis of novel 2-acetamide-5-phenylthio-1,3,4-thiadiazole-containing phenyl urea derivatives as potential VEGFR-2 inhibitors

Autor: Mahsa Toolabi, Fatemeh Safari, Adileh Ayati, Parnian Fathi, Setareh Moghimi, Somayeh Salarinejad, Roham Foroumadi, Shima H. M. E. Ketabforoosh, Alireza Foroumadi

Publikováno v: Archiv der PharmazieREFERENCES. 355(3)

A novel series of 2-acetamide-5-phenylthio-1,3,4-thiadiazol derivatives containing a phenyl urea warhead were synthesized and evaluated as antiproliferative agents. The cytotoxic activities of the newly synthesized compounds were evaluated toward thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76601f61e1380f13716a0cc0460e031
https://pubmed.ncbi.nlm.nih.gov/35014090

Zobrazit plný text záznamu

2-(Bipiperidin-1-yl)-5-(nitroaryl)-1,3,4-thiadiazoles: Synthesis, evaluation of in vitro leishmanicidal activity, and mechanism of action

Autor: Sussan Kaboudanian-Ardestani, Setareh Moghimi, Mahsa Toolabi, Fereshteh Goli, Zahra Mojallal-Tabatabaei, Parham Foroumadi, Alireza Foroumadi

Publikováno v: Bioorganic & Medicinal Chemistry. 27:3682-3691

The development of novel leishmanicidal agents that are capable of being replaced by the available therapeutic options has become a priority. In the present study, the synthesis and leishmanicidal activity of a series of 5-(nitroheteroaryl-2-yl)-1,3,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2581ead8d98992aa39cb839928bfa2d0
https://doi.org/10.1016/j.bmc.2019.07.009

Zobrazit plný text záznamu

Design, synthesis, molecular docking study, and antibacterial evaluation of some new fluoroquinolone analogues bearing a quinazolinone moiety

Autor: Gizem Şanlıtürk, Mahsa Toolabi, Mümtaz Güran, Maryam Norouzbahari, Somayeh Salarinejad, Hamid Reza Bijanzadeh, Zahra Emamgholipour, Alireza Foroumadi

Publikováno v: Daru

BACKGROUND: Increasing bacterial resistance to quinolones is concerning. Hence, the development of novel quinolones by chemical modifications to overcome quinolone resistance is an attractive perspective in this context. OBJECTIVE: In this study, it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851543f14ff2c7582ba758a5b23eb2ea
https://europepmc.org/articles/PMC7704824/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání