Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mahsa Moaddab"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Moaddab et al. monitored single-unit firing of ventral pallidum (VP) neurons alongside behavior in rats when presented with auditory cues of various threat levels. They show that the VP is comprised of functional neuronal populations that dynamically
Externí odkaz:
https://doaj.org/article/996c9d6894f34284bda174cadf7dab7d
Publikováno v:
Basic and Clinical Neuroscience, Vol 4, Iss 2, Pp 159-168 (2013)
This study has examined the functional importance of nucleus accumbens (NAc)-ventral tegmental area (VTA) interactions. As it is known, this interaction is important in associative reward processes. Under urethane anesthesia, extracellular single uni
Externí odkaz:
https://doaj.org/article/b9a4fe5e6d3549d7a94bed4e667f2d6b
Publikováno v:
Brain Sciences, Vol 7, Iss 11, p 151 (2017)
Adolescent alcohol drinking increases the risk for alcohol-use disorder in adulthood. Yet, the changes in adult neural function resulting from adolescent alcohol drinking remain poorly understood. We hypothesized that adolescent alcohol drinking alte
Externí odkaz:
https://doaj.org/article/7421b2350a3d4a96aa8001980e461db3
Publikováno v:
bioRxiv
Behavioral responding is most beneficial when it reflects event timing. Compared to reward, there are fewer studies on timing of defensive responding. We gave female and male rats Pavlovian fear conditioning over a baseline of reward seeking. Two 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f2c180cc7da91047ee5af5b8ba6cef
https://europepmc.org/articles/PMC9900810/
https://europepmc.org/articles/PMC9900810/
Publikováno v:
J Neurosci
Appropriate responding to threat and reward is essential to survival. The nucleus accumbens core (NAcc) is known to support and organize reward behavior. The NAcc is also necessary to fully discriminate threat and safety cues. To directly reveal NAcc
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Early adolescent adversity increases adult risk for anxiety disorders. The ventrolateral periaqueductal gray (vlPAG) and neighboring dorsal raphe (DR) are integral to threat prediction, and are responsive to acute stressors. Here, we tested the hypot
Appropriate responding to threat and reward is essential to survival. The nucleus accumbens core (NAcc) is known to support and organize reward behavior. More recently our laboratory has shown the NAcc is necessary to discriminate cues for threat and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::181d0e4d296233d14319c79a762ba317
https://doi.org/10.1101/2021.05.27.446063
https://doi.org/10.1101/2021.05.27.446063
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
The ventral pallidum (VP) is anatomically poised to contribute to threat behavior. Recent studies report a VP population that scales firing increases to reward but decreases firing to aversive cues. Here, we tested whether firing decreases in VP neur
Ventral pallidum (VP) neurons scale firing increases to reward value and decrease firing to aversive cues. Anatomical connectivity suggests a critical role for the VP in threat-related behavior. Here we tested whether firing decreases in VP neurons c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a20c65b3be851cf58a5c19e6d03bc0d
https://doi.org/10.1101/2020.06.04.135145
https://doi.org/10.1101/2020.06.04.135145
Autor:
Mahsa Moaddab, Joanna Dabrowska
Publikováno v:
Neuropharmacology. 121:130-139
Oxytocin (OT) is a hypothalamic neuropeptide that modulates fear and anxiety-like behaviors. Dorsolateral bed nucleus of the stria terminalis (BNSTdl) plays a critical role in the regulation of fear and anxiety, and expresses high levels of OT recept